{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T01:28:20Z","timestamp":1792978100229,"version":"4.5.0"},"reference-count":50,"publisher":"American Chemical Society (ACS)","issue":"36","license":[{"start":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T00:00:00Z","timestamp":1662336000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T00:00:00Z","timestamp":1662336000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T00:00:00Z","timestamp":1662336000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100017531","name":"Medical and Health Research Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2020RC125"],"award-info":[{"award-number":["2020RC125"]}],"id":[{"id":"10.13039\/501100017531","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LBQ20H060001"],"award-info":[{"award-number":["LBQ20H060001"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LBY22H180011"],"award-info":[{"award-number":["LBY22H180011"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LBZ22H180001"],"award-info":[{"award-number":["LBZ22H180001"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Jiaxing Public Welfare Research Program","award":["2020AY30021"],"award-info":[{"award-number":["2020AY30021"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2022,9,14]]},"DOI":"10.1021\/acsami.2c12703","type":"journal-article","created":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T10:10:41Z","timestamp":1662372641000},"page":"40711-40723","source":"Crossref","is-referenced-by-count":107,"title":["Nanoarchitectonics of Cartilage-Targeting Hydrogel Microspheres with Reactive Oxygen Species Responsiveness for the Repair of Osteoarthritis"],"prefix":"10.1021","volume":"14","author":[{"given":"Han","family":"Yu","sequence":"first","affiliation":[{"name":"Zhejiang Chinese Medical University, Hangzhou 310000, China"},{"name":"Department of Orthopaedics, Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenglong","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangjia","family":"Kong","sequence":"additional","affiliation":[{"name":"Zhejiang Chinese Medical University, Hangzhou 310000, China"},{"name":"Department of Orthopaedics, Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Ma","sequence":"additional","affiliation":[{"name":"Zhejiang Chinese Medical University, Hangzhou 310000, China"},{"name":"Department of Orthopaedics, Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5941-0907","authenticated-orcid":true,"given":"Huanhuan","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,9,5]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1903768"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)30417-9"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32230-3"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-021-00724-w"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1080\/13880209.2018.1557700"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.120155"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.22171"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.34133\/2021\/4189516"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b08057"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13020290"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-03765-x"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1080\/1061186X.2018.1464011"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.120539"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-17242-0"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/bs.acc.2020.04.002"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1039\/C9NR03060C"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.1c00005"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119605"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.7150\/thno.40395"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2021.608150"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b05214"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.03.010"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b12395"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b12025"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1039\/C9AN00243J"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-017-0275-4"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201901239"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.03.010"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2020.08.026"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.engreg.2021.03.002"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.01.019"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2018.03.007"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.34133\/2020\/7659749"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.03.022"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.0c04713"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1088\/1758-5090\/abc4d3"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.engreg.2021.10.002"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2020.126004"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.05.024"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.01.017"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119520"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2017-0335"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/nmat2116"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.121194"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202100873"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c02082"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202100479"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202004519"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202107678"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1177\/0363546510378088"}],"container-title":["ACS Applied Materials &amp; Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.2c12703","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.2c12703","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T23:18:03Z","timestamp":1682551083000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.2c12703"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,5]]},"references-count":50,"journal-issue":{"issue":"36","published-print":{"date-parts":[[2022,9,14]]}},"alternative-id":["10.1021\/acsami.2c12703"],"URL":"https:\/\/doi.org\/10.1021\/acsami.2c12703","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,5]]}}}