{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T22:09:49Z","timestamp":1783116589794,"version":"3.54.6"},"reference-count":54,"publisher":"American Chemical Society (ACS)","issue":"1","license":[{"start":{"date-parts":[[2022,12,26]],"date-time":"2022-12-26T00:00:00Z","timestamp":1672012800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,26]],"date-time":"2022-12-26T00:00:00Z","timestamp":1672012800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,26]],"date-time":"2022-12-26T00:00:00Z","timestamp":1672012800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["G2021029011L"],"award-info":[{"award-number":["G2021029011L"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21574105"],"award-info":[{"award-number":["21574105"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81371675"],"award-info":[{"award-number":["81371675"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010250","name":"Sichuan Province Youth Science and Technology Innovation Team","doi-asserted-by":"crossref","award":["2016TD0026"],"award-info":[{"award-number":["2016TD0026"]}],"id":[{"id":"10.13039\/501100010250","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2023,1,11]]},"DOI":"10.1021\/acsami.2c16616","type":"journal-article","created":{"date-parts":[[2022,12,26]],"date-time":"2022-12-26T08:33:30Z","timestamp":1672043610000},"page":"2030-2042","source":"Crossref","is-referenced-by-count":18,"title":["Folate Decoration Supports the Targeting of Camptothecin Micelles against Activated Hepatic Stellate Cells and the Suppression of Fibrogenesis"],"prefix":"10.1021","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5823-987X","authenticated-orcid":true,"given":"Li","family":"Xiang","sequence":"first","affiliation":[{"name":"Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaru","family":"Shao","sequence":"additional","affiliation":[{"name":"Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, School of Pharmaceutic Sciences, University of South China, Hengyang, Hunan 421001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiangqiang","family":"Jiao","sequence":"additional","affiliation":[{"name":"Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, School of Pharmaceutic Sciences, University of South China, Hengyang, Hunan 421001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Cheng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotong","family":"Zheng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaobing","family":"Zhou","sequence":"additional","affiliation":[{"name":"Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4810-1922","authenticated-orcid":true,"given":"Yuping","family":"Chen","sequence":"additional","affiliation":[{"name":"Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China"},{"name":"Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, School of Pharmaceutic Sciences, University of South China, Hengyang, Hunan 421001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,12,26]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-020-00372-7"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i23.7242"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3390\/nano10101945"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2304-3881.2014.11.02"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.3390\/cells9010024"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2017.11.178"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/4674046"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23419"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.107.122481"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2011.86"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2016.02.029"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/nn100589y"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119616"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.118.256156"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1396"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2004.06.009"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.02.023"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.21712"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.05.071"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27376"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.05.028"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/C6RA11824K"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1039\/C5PY00156K"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0138655"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.02.071"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2017.06.003"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2018.05.032"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c00764"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.05.034"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-018-0234-x"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119486"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1039\/C8BM01042K"},{"key":"ref33\/cit33","first-page":"28","volume":"13","author":"Miladi K.","year":"2014","journal-title":"Excli J."},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2004.01.008"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1033"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.07.115"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201200765"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2013.08.071"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201402870"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1002\/0471140856.tx1412s62"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00013.2007"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1172\/JCI67230"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.5b02297"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2004.12.026"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1396"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2016.02.029"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2016.00033"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/nrd4592"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2010.11.004"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/srep29460"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/nn9010973"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1007\/s13346-013-0178-3"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22952"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.01.010"}],"container-title":["ACS Applied Materials &amp; Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.2c16616","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.2c16616","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T14:09:11Z","timestamp":1682604551000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.2c16616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,26]]},"references-count":54,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1,11]]}},"alternative-id":["10.1021\/acsami.2c16616"],"URL":"https:\/\/doi.org\/10.1021\/acsami.2c16616","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,26]]}}}