{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T20:59:18Z","timestamp":1792875558122,"version":"4.5.0"},"reference-count":57,"publisher":"American Chemical Society (ACS)","issue":"20","license":[{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"vor","delay-in-days":365,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016017","name":"Duke-NUS Medical School","doi-asserted-by":"publisher","award":["KPFA\/2018\/0028"],"award-info":[{"award-number":["KPFA\/2018\/0028"]}],"id":[{"id":"10.13039\/100016017","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004327","name":"SingHealth Foundation","doi-asserted-by":"publisher","award":["SHF\/FG661P\/2017"],"award-info":[{"award-number":["SHF\/FG661P\/2017"]}],"id":[{"id":"10.13039\/501100004327","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2024,5,22]]},"DOI":"10.1021\/acsami.4c04077","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T19:35:01Z","timestamp":1715628901000},"page":"25892-25908","source":"Crossref","is-referenced-by-count":9,"title":["Nanohydroxyapatite Coating Attenuates Fibrotic and Immune Responses to Promote Keratoprosthesis Biointegration in Advanced Ocular Surface Disorders"],"prefix":"10.1021","volume":"16","author":[{"given":"Arun J.","family":"Thirunavukarasu","sequence":"first","affiliation":[{"name":"Tissue Engineering and Cell Therapy Group","place":["Singapore, Singapore"]},{"name":"Singapore Eye Research Institute","place":["Singapore, Singapore"]},{"name":"Oxford University Clinical Academic Graduate School","place":["Oxford, United Kingdom"]},{"name":"University of Oxford","place":["Oxford, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Morales-Wong","sequence":"additional","affiliation":[{"name":"Tissue Engineering and Cell Therapy Group","place":["Singapore, Singapore"]},{"name":"Singapore Eye Research Institute","place":["Singapore, Singapore"]},{"name":"Singapore National Eye Centre","place":["Singapore, Singapore"]},{"name":"Autonomous University of Nuevo Leon","place":["San Nicolas de los Garza, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuur Shahinda Humaira binte","family":"Halim","sequence":"additional","affiliation":[{"name":"Tissue Engineering and Cell Therapy Group","place":["Singapore, Singapore"]},{"name":"Singapore Eye Research Institute","place":["Singapore, Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelina","family":"Han","sequence":"additional","affiliation":[{"name":"Tissue Engineering and Cell Therapy Group","place":["Singapore, Singapore"]},{"name":"Singapore Eye Research Institute","place":["Singapore, Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siew Kwan","family":"Koh","sequence":"additional","affiliation":[{"name":"Ocular Proteomics Group","place":["Singapore, Singapore"]},{"name":"Singapore Eye Research Institute","place":["Singapore, Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Applied Biology and Chemical Technology","place":["Hung Hom, Hong Kong"]},{"name":"Hong Kong Polytechnic University","place":["Hung Hom, Hong Kong"]},{"name":"Centre for Eye and Vision Research","place":["Shatin, Hong Kong"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viridiana","family":"Kocaba","sequence":"additional","affiliation":[{"name":"Tissue Engineering and Cell Therapy Group","place":["Singapore, Singapore"]},{"name":"Singapore Eye Research Institute","place":["Singapore, Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subramanian","family":"Venkatraman","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]},{"name":"iHealthTech","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jodhbir S.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Tissue Engineering and Cell Therapy Group","place":["Singapore, Singapore"]},{"name":"Singapore Eye Research Institute","place":["Singapore, Singapore"]},{"name":"Singapore National Eye Centre","place":["Singapore, Singapore"]},{"name":"Ophthalmology and Visual Sciences Academic Clinical Programme","place":["Singapore, Singapore"]},{"name":"Duke-NUS Medical School","place":["Singapore, Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5105-0484","authenticated-orcid":true,"given":"Andri K.","family":"Riau","sequence":"additional","affiliation":[{"name":"Tissue Engineering and Cell Therapy Group","place":["Singapore, Singapore"]},{"name":"Singapore Eye Research Institute","place":["Singapore, Singapore"]},{"name":"Ophthalmology and Visual Sciences Academic Clinical Programme","place":["Singapore, Singapore"]},{"name":"Duke-NUS Medical School","place":["Singapore, Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,5,13]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2015.4776"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1080\/02713683.2019.1663874"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2018.01.023"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2023.07.053"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2018.05.010"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.121.8.1087"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S27083"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3129\/i08-009"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-vision-100820-021253"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2019.03.016"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10300"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1093\/rb\/rbz044"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2020-317598"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(98)00069-6"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-27492011000200012"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200307000-00007"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/196827"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000837"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-014-5347-5"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198712000-00014"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.11-7601"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jma.2023.09.033"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0111503"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S245500"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2020.01.023"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.3390\/ma12111795"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3390\/nano10112162"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000001352"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1007\/s11666-020-01009-6"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.surfcoat.2021.127098"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.6b12371"},{"key":"ref32\/cit32","first-page":"635","volume":"9","author":"Du Y.","year":"2003","journal-title":"Mol. Vision"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200308000-00009"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-3860"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2004.08.002"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2023.09.002"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.18-25761"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2005.12.009"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1093\/rb\/rbv014"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2009.11.012"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.5b07621"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1002\/admi.201900767"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1097\/ICL.0000000000000641"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2021.05.005"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.3390\/polym12102198"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2014.1959"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens8030093"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1039\/C7TB02363D"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820281115"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.31096"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2012.11.025"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2021.05.022"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1177\/0391398818762349"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1089\/jop.2017.0108"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-35096-x"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.euprot.2015.02.002"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2003-4-5-p3"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.4c04077","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.4c04077","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T06:29:14Z","timestamp":1747117754000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.4c04077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,13]]},"references-count":57,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2024,5,22]]}},"alternative-id":["10.1021\/acsami.4c04077"],"URL":"https:\/\/doi.org\/10.1021\/acsami.4c04077","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,13]]}}}