{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T02:54:41Z","timestamp":1792119281574,"version":"4.4.0"},"reference-count":54,"publisher":"American Chemical Society (ACS)","issue":"27","license":[{"start":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T00:00:00Z","timestamp":1719360000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T00:00:00Z","timestamp":1719360000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T00:00:00Z","timestamp":1719360000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100017366","name":"Key Research and Development Program of Heilongjiang","doi-asserted-by":"publisher","award":["2022ZX02005"],"award-info":[{"award-number":["2022ZX02005"]}],"id":[{"id":"10.13039\/100017366","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2024,7,10]]},"DOI":"10.1021\/acsami.4c04416","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T22:45:09Z","timestamp":1719441909000},"page":"34524-34537","source":"Crossref","is-referenced-by-count":50,"title":["Polystyrene Nanoplastics Induce Lipid Metabolism Disorder by Activating the PERK-ATF4 Signaling Pathway in Mice"],"prefix":"10.1021","volume":"16","author":[{"given":"Ziteng","family":"Yu","sequence":"first","affiliation":[{"name":"School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingpei","family":"Fan","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyue","family":"He","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Li","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haining","family":"Du","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meimei","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijiao","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengcong","family":"Li","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyi","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4130-3625","authenticated-orcid":true,"given":"Fang","family":"Han","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,6,26]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","unstructured":"Kozlov, M. Landmark study links microplastics to serious health problems\n                      Nature\n                      2024 10.1038\/d41586-024-00650-3.","DOI":"10.1038\/d41586-024-00650-3"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2017.11.043"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1126\/science.abe0290"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2018.08.178"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2017.01.190"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.3390\/toxics9090224"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1080\/19440049.2013.843025"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.138707"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2022.107362"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.142518"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3390\/toxics10100586"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2012.5149"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2023.115447"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.132503"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-023-30155-x"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2023.123086"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-020-10121-2"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2017.11.103"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24087382"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-019-02478-7"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","unstructured":"Sun, W.; Lei, Y.; Jiang, Z. BPA and low-Se exacerbate apoptosis and mitophagy in chicken pancreatic cells by regulating the PTEN\/PI3K\/AKT\/mTOR pathway\n                      J. Adv. Res.\n                      2024 10.1016\/j.jare.2024.01.029.","DOI":"10.1016\/j.jare.2024.01.029"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.171817"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/etc.5767"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2024.116389"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2021.132607"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2021.126454"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c09729"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2020.115946"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.172037"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2016.04.026"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-018-1510-z"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.marpolbul.2023.115784"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.9b01474"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1530\/JOE-23-0365"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.cld.2012.03.006"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(59)90175-5"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21768"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfae021"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1177\/11786302241235810"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2024.133855"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.0c07384"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2020.124004"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1975.tb51092.x"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2023.108391"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M604709200"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-2129"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2023.117472"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-310798"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1210\/er.2018-00064"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.REV118.002804"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2199"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2022.121149"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.470526"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2015.01.015"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.4c04416","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.4c04416","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T05:34:53Z","timestamp":1720589693000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.4c04416"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,26]]},"references-count":54,"journal-issue":{"issue":"27","published-print":{"date-parts":[[2024,7,10]]}},"alternative-id":["10.1021\/acsami.4c04416"],"URL":"https:\/\/doi.org\/10.1021\/acsami.4c04416","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,26]]}}}