{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:57:24Z","timestamp":1787000244480,"version":"build-2736575974"},"reference-count":43,"publisher":"American Chemical Society (ACS)","issue":"11","license":[{"start":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T00:00:00Z","timestamp":1741046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T00:00:00Z","timestamp":1741046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T00:00:00Z","timestamp":1741046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["45\/6\/2019-NAN-BMS"],"award-info":[{"award-number":["45\/6\/2019-NAN-BMS"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","award":["CRG\/2019\/004018"],"award-info":[{"award-number":["CRG\/2019\/004018"]}],"id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002383","name":"King Saud University","doi-asserted-by":"publisher","award":["RSPD2025R940"],"award-info":[{"award-number":["RSPD2025R940"]}],"id":[{"id":"10.13039\/501100002383","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2025,3,19]]},"DOI":"10.1021\/acsami.4c20973","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T23:46:01Z","timestamp":1741131961000},"page":"16590-16601","source":"Crossref","is-referenced-by-count":6,"title":["Engineered Drug-Amphiphile Conjugate Nanoparticles for Targeted Inhibition of AQP4-Mediated NLRP3 Inflammasome Signaling in Collagen-Induced Rheumatoid Arthritis"],"prefix":"10.1021","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7649-4578","authenticated-orcid":true,"given":"Ajay","family":"Kumar","sequence":"first","affiliation":[{"name":"Chemical Biology Unit, Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali (SAS Nagar), Punjab 140306, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5538-1830","authenticated-orcid":true,"family":"Rahul","sequence":"additional","affiliation":[{"name":"Chemical Biology Unit, Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali (SAS Nagar), Punjab 140306, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Kanika","sequence":"additional","affiliation":[{"name":"Chemical Biology Unit, Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali (SAS Nagar), Punjab 140306, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jattin","family":"Kumar","sequence":"additional","affiliation":[{"name":"Chemical Biology Unit, Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali (SAS Nagar), Punjab 140306, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1105-7526","authenticated-orcid":true,"given":"Anas","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Julia McFarlane Diabetes Research Centre (JMDRC) and Department of Microbiology, Immunology and Infectious Diseases, Snyder Institute for Chronic Diseases, and Hotchkiss Brain Institute","place":["Calgary, Canada"]},{"name":"Cumming School of Medicine, University of Calgary","place":["Calgary, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aneesh","family":"Ali","sequence":"additional","affiliation":[{"name":"Chemical Biology Unit, Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali (SAS Nagar), Punjab 140306, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhuvnesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Chemical Biology Unit, Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali (SAS Nagar), Punjab 140306, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubham","family":"Mahajan","sequence":"additional","affiliation":[{"name":"Chemical Biology Unit, Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali (SAS Nagar), Punjab 140306, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nemat","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Pharmacology & Toxicology, College of Pharmacy","place":["Riyadh, Saudi Arabia"]},{"name":"King Saud University","place":["Riyadh, Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2406-1129","authenticated-orcid":true,"given":"Rehan","family":"Khan","sequence":"additional","affiliation":[{"name":"Chemical Biology Unit, Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali (SAS Nagar), Punjab 140306, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,3,4]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.18053\/jctres.02.201603.005"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1186\/s12950-017-0153-8"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.00101"},{"issue":"5","key":"ref4\/cit4","first-page":"563","volume":"47","author":"Cai L.","year":"2017","journal-title":"Ann. Clin. Lab. Sci."},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2022.103131"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2008.11.010"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110985"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.580593"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.3390\/nu12051479"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.0c00807"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.9b00427"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03691-1"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.122747"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.3c00514"},{"key":"ref15\/cit15","unstructured":"Recent Progress in Microenvironment-Responsive\nNanodrug Delivery\nSystems for the Targeted Treatment of Rheumatoid Arthritis - Liu -\n2024 - WIREs Nanomedicine and Nanobiotechnology - Wiley Online Library\n                      . https:\/\/wires.onlinelibrary.wiley.com\/doi\/epdf\/10.1002\/wnan.2008 (accessed Jan 26, 2025)."},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202401936"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1039\/D0TB01559H"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-15-93"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1285455"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.169.5.2643"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2016.1161620"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21249739"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/3830212"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","unstructured":"Synovial fluid matrix metalloproteinase-3 levels are increased in\ninflammatory arthritides whether erosive or not | Rheumatology | Oxford\nAcademic\n                      . https:\/\/academic.oup.com\/rheumatology\/article-abstract\/39\/12\/1357\/1784191?redirectedFrom=fulltext (accessed July 10, 2024).","DOI":"10.1093\/rheumatology\/39.12.1357"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1111\/sji.12982"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-8077.2007.00305.x"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.591365"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-020-0419-z"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1007\/s40744-020-00219-2"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/765624"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2021.155742"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1039\/D2BM01994A"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.9b00496"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28114414"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/39.9.1004"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1038\/srep14713"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2024.123215"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.46497\/ArchRheumatol.2022.8688"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2023.05.003"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2015.02.029"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1039\/D3NR03857B"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-1413-8"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1402321"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.4c20973","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.4c20973","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T04:15:48Z","timestamp":1742357748000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.4c20973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,4]]},"references-count":43,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,3,19]]}},"alternative-id":["10.1021\/acsami.4c20973"],"URL":"https:\/\/doi.org\/10.1021\/acsami.4c20973","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,4]]}}}