{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T22:41:40Z","timestamp":1793054500423,"version":"4.5.0"},"reference-count":44,"publisher":"American Chemical Society (ACS)","issue":"18","funder":[{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology, Ministry of Science and Technology","doi-asserted-by":"publisher","award":["DST\/INT\/JSPS\/P-160\/2013"],"award-info":[{"award-number":["DST\/INT\/JSPS\/P-160\/2013"]}],"id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["DST\/INT\/JSPS\/P-160\/2013"],"award-info":[{"award-number":["DST\/INT\/JSPS\/P-160\/2013"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001412","name":"Council of Scientific and Industrial Research","doi-asserted-by":"publisher","award":["9\/963(0034)2K13-EMR-I"],"award-info":[{"award-number":["9\/963(0034)2K13-EMR-I"]}],"id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2015,5,13]]},"DOI":"10.1021\/acsami.5b02685","type":"journal-article","created":{"date-parts":[[2015,4,20]],"date-time":"2015-04-20T21:35:21Z","timestamp":1429565721000},"page":"9399-9409","source":"Crossref","is-referenced-by-count":147,"title":["Injectable Chitin-Poly(\u03b5-caprolactone)\/Nanohydroxyapatite Composite Microgels Prepared by Simple Regeneration Technique for Bone Tissue Engineering"],"prefix":"10.1021","volume":"7","author":[{"given":"R.","family":"Arun Kumar","sequence":"first","affiliation":[{"name":"Amrita Centre for Nanosciences and Molecular Medicine,\rAmrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham University, Kochi-682041, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Sivashanmugam","sequence":"additional","affiliation":[{"name":"Amrita Centre for Nanosciences and Molecular Medicine,\rAmrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham University, Kochi-682041, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Deepthi","sequence":"additional","affiliation":[{"name":"Amrita Centre for Nanosciences and Molecular Medicine,\rAmrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham University, Kochi-682041, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachiko","family":"Iseki","sequence":"additional","affiliation":[{"name":"Section of Molecular Craniofacial Embryology,\rGraduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo-113-8549, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. P.","family":"Chennazhi","sequence":"additional","affiliation":[{"name":"Amrita Centre for Nanosciences and Molecular Medicine,\rAmrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham University, Kochi-682041, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shantikumar V.","family":"Nair","sequence":"additional","affiliation":[{"name":"Amrita Centre for Nanosciences and Molecular Medicine,\rAmrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham University, Kochi-682041, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Jayakumar","sequence":"additional","affiliation":[{"name":"Amrita Centre for Nanosciences and Molecular Medicine,\rAmrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham University, Kochi-682041, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2015,4,30]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0090-3019(03)00031-4","volume":"60","author":"Artico M.","year":"2003","journal-title":"Surg. Neurol."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/00003086-199603000-00009","volume":"324","author":"Stevenson S.","year":"1996","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"E19","DOI":"10.3171\/2014.2.FOCUS13561","volume":"36","author":"Shah A. M.","year":"2014","journal-title":"Neurosurg. Focus."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"162","DOI":"10.4103\/0976-3147.83584","volume":"2","author":"Aydin S.","year":"2011","journal-title":"J. Neurosci. Rural Pract."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1021\/bm200083n","volume":"12","author":"Van Vlierberghe S.","year":"2011","journal-title":"Biomacromolecules"},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.biomaterials.2013.10.016","volume":"35","author":"Ni P. Y.","year":"2014","journal-title":"Biomaterials"},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1016\/j.polymer.2008.01.027","volume":"49","author":"Hoare T. R.","year":"2008","journal-title":"Polymer"},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"3368","DOI":"10.1002\/adma.200802009","volume":"21","author":"Kretlow J. D.","year":"2009","journal-title":"Adv. Mater."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1080\/00206811003679521","volume":"52","author":"Ehrlich H.","year":"2010","journal-title":"Int. Geol. Rev."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ijbiomac.2010.05.009","volume":"47","author":"Ehrlich H.","year":"2010","journal-title":"Int. J. Biol. Macromol."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3390\/polym7020235","volume":"7","author":"Wysokowski M.","year":"2015","journal-title":"Polymers"},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.carbpol.2010.04.074","volume":"82","author":"Jayakumar R.","year":"2010","journal-title":"Carbohydr. Polym."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/j.progpolymsci.2010.04.002","volume":"35","author":"Woodruff M. A.","year":"2010","journal-title":"Prog. Polym. Sci."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1007\/s00198-009-0860-y","volume":"20","author":"Rey C.","year":"2009","journal-title":"Osteoporosis Int."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1089\/ten.teb.2012.0624","volume":"19","author":"Zakaria S. M.","year":"2013","journal-title":"Tissue Eng., Part B"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"8363","DOI":"10.1016\/j.biomaterials.2012.08.023","volume":"33","author":"Fu S. Z.","year":"2012","journal-title":"Biomaterials"},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"4801","DOI":"10.1016\/j.biomaterials.2012.03.040","volume":"33","author":"Fu S. Z.","year":"2012","journal-title":"Biomaterials"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.carbpol.2011.08.044","volume":"87","author":"Rejinold N. S.","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/1-4020-3689-2_9","volume-title":"Molecular Gels","author":"Raghavan S. R.","year":"2006"},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.carbpol.2009.11.050","volume":"80","author":"Peter M.","year":"2010","journal-title":"Carbohydr. Polym."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1016\/j.bjps.2012.06.011","volume":"65","author":"Uysal C. A.","year":"2012","journal-title":"J. Plast. Reconstr. Aesthetic Surg."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0022-1759(97)00043-4","volume":"204","author":"Nakayama G. R.","year":"1997","journal-title":"J. Immunol. Methods"},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nprot.2007.30","volume":"2","author":"Liang C. C.","year":"2007","journal-title":"Nat. Protoc."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1039\/C1JM14038H","volume":"22","author":"Soumya S.","year":"2012","journal-title":"J. Mater. Chem."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1002\/pi.1380","volume":"52","author":"Honma T.","year":"2003","journal-title":"Polym. Int."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.ijbiomac.2007.09.003","volume":"43","author":"Jayakumar R.","year":"2008","journal-title":"Int. J. Biol. Macromol."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.mseb.2004.04.011","volume":"111","author":"Kim I. S.","year":"2004","journal-title":"Mater. Sci. Eng., B"},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1002\/pi.793","volume":"51","author":"Senda T.","year":"2002","journal-title":"Polym. Int."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.partic.2009.06.008","volume":"7","author":"Padmanabhan S. K.","year":"2009","journal-title":"Particuology"},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1080\/00268979100102721","volume":"74","author":"Rehage H.","year":"1991","journal-title":"Mol. Phys."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/0095-8522(65)90022-X","volume":"20","author":"Cross M. M.","year":"1965","journal-title":"J. Colloid Interface Sci."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"4749","DOI":"10.1016\/j.biomaterials.2003.12.005","volume":"25","author":"Wei G.","year":"2004","journal-title":"Biomaterials"},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/0003-2697(84)90241-0","volume":"136","author":"Gorbunoff M. J.","year":"1984","journal-title":"Anal. Biochem."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"2622","DOI":"10.1016\/j.biomaterials.2007.02.004","volume":"28","author":"Woo K. M.","year":"2007","journal-title":"Biomaterials"},{"key":"ref35\/cit35","first-page":"605","author":"Woo K. M.","year":"2002","journal-title":"Trans. 28th Annu. Meet. Soc. Biomater."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/SLA.0b013e3181ae9d45","volume":"250","author":"Scherer S. S.","year":"2009","journal-title":"Ann. Surg."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1016\/j.progpolymsci.2014.02.008","volume":"39","author":"Anitha A.","year":"2014","journal-title":"Prog. Polym. Sci."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1634\/stemcells.2005-0342","volume":"24","author":"Kern S.","year":"2006","journal-title":"Stem Cells"},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1089\/ten.tea.2011.0176","volume":"18","author":"Dormer N. H.","year":"2011","journal-title":"Tissue Eng., Part A"},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1111\/j.1600-0765.2011.01443.x","volume":"47","author":"An S.","year":"2012","journal-title":"J. Periodontal Res."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"3780","DOI":"10.1039\/b705129h","volume":"17","author":"Cai Y.","year":"2007","journal-title":"J. Mater. Chem."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1002\/jcb.10622","volume":"90","author":"Beck G. R.","year":"2003","journal-title":"J. Cell. Biochem."},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1177\/0022034508328072","volume":"88","author":"Fatherazi S.","year":"2009","journal-title":"J. Dent. Res."},{"key":"ref44\/cit44","first-page":"25","volume":"53","author":"Sila-Asna M.","year":"2007","journal-title":"Kobe J. Med. Sci."}],"container-title":["ACS Applied Materials &amp; Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5b02685","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T04:49:11Z","timestamp":1681534151000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.5b02685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,30]]},"references-count":44,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2015,5,13]]}},"alternative-id":["10.1021\/acsami.5b02685"],"URL":"https:\/\/doi.org\/10.1021\/acsami.5b02685","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,30]]}}}