{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T19:53:44Z","timestamp":1793390024783,"version":"4.5.0"},"reference-count":83,"publisher":"American Chemical Society (ACS)","issue":"18","license":[{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100004681","name":"Higher Education Commission, Pakistan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004681","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2025,5,7]]},"DOI":"10.1021\/acsami.5c00453","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T13:33:44Z","timestamp":1745501624000},"page":"26263-26281","source":"Crossref","is-referenced-by-count":5,"title":["Saponin Gallate-Loaded Gd-Doped Zinc\u2013Gallium Layered Double Hydroxides (Zn\/Ga@Gd-LDH) Nanocarrier for Attenuating NF-\u03baB-Mediated Inflammation"],"prefix":"10.1021","volume":"17","author":[{"given":"Momna","family":"Aslam","sequence":"first","affiliation":[{"name":"Department of Biochemistry","place":["Multan, Pakistan"]},{"name":"Bahauddin Zakariya University","place":["Multan, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3877-5090","authenticated-orcid":true,"given":"Batool","family":"Fatima","sequence":"additional","affiliation":[{"name":"Department of Biochemistry","place":["Multan, Pakistan"]},{"name":"Bahauddin Zakariya University","place":["Multan, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafia","family":"Batool","sequence":"additional","affiliation":[{"name":"Department of Biochemistry","place":["Multan, Pakistan"]},{"name":"Bahauddin Zakariya University","place":["Multan, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Imran","sequence":"additional","affiliation":[{"name":"Institute of Chemical Sciences","place":["Peshawar, Pakistan"]},{"name":"University of Peshawar","place":["Peshawar, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6187-5626","authenticated-orcid":true,"given":"Dilshad","family":"Hussain","sequence":"additional","affiliation":[{"name":"HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences","place":["Karachi, Pakistan"]},{"name":"University of Karachi","place":["Karachi, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2090-5072","authenticated-orcid":true,"given":"Muhammad","family":"Najam-ul-Haq","sequence":"additional","affiliation":[{"name":"Institute of Chemical Sciences","place":["Multan, Pakistan"]},{"name":"Bahauddin Zakariya University","place":["Multan, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubaida","family":"Mehmood","sequence":"additional","affiliation":[{"name":"MINAR Cancer Hospital Multan","place":["Multan, Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.02.029"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23094596"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.06.025"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.126"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-008-8091-0"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2020.153411"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.688780"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10121998"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2021.05.012"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.104"},{"key":"ref11\/cit11","volume-title":"Acute inflammatory response","author":"Hannoodee S.","year":"2020"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1172\/JCI124616"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/bs.apcsb.2019.09.004"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2019.01399"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.574706"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00658-5"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25245932"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15153900"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1201\/9781003418276-4"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110985"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2019.11.202"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-021-00866-8"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1080\/09603123.2020.1805415"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1039\/b902861g"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.3390\/polym3031377"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics10020057"},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.jconrel.2020.12.041","volume":"330","author":"Shirin V. A.","year":"2021","journal-title":"J. Controlled Release"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1039\/C9TB01312A"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.3390\/nano7090244"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S220202"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiec.2021.08.012"},{"issue":"1","key":"ref32\/cit32","first-page":"12","volume":"8","author":"Paarakh M. P.","year":"2018","journal-title":"Int. J. Pharm. Res. Tech. (IJPRT)"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1006\/fstl.1997.0240"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26051244"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.2174\/1573409918666220929145824"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2023.104708"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2019.9967"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2020.11240"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1093\/toxres\/tfac059"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxrep.2021.01.001"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-022-03554-9"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-021-03479-9"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1177\/09603271211054436"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3390\/nano11123260"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2016.09.089"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2018.11.035"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-71175-8"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.26717\/BJSTR.2020.27.004463"},{"issue":"2","key":"ref49\/cit49","first-page":"1","volume":"3","author":"Rajvanshi S. K.","year":"2017","journal-title":"Int. J. Minor Fruits, Med. Aromatic Plants"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2022.111026"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.3390\/ijms161024673"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.4236\/jbm.2019.77006"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1007\/s12517-021-09275-6"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2014.992345"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-13-0118"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.matchemphys.2019.122232"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S95611"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1039\/C6TB03032G"},{"issue":"1","key":"ref59\/cit59","first-page":"77","volume":"2","author":"Singhvi G.","year":"2011","journal-title":"Int. J. Pharm. Stud. Res."},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.33263\/BRIAC116.1464014660"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.34874\/PRSM.mjph-vol3iss2.30290"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(02)00393-X"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.22038\/ijbms.2019.32806.7897"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0227950"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2016.217"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-08-0149"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2011.12.005"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-020-00312-6"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1101\/gad.183434.111"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110525"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/4951937"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1093\/jpp\/rgab117"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1016\/j.phyplu.2020.100017"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2020.101809"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1002\/VIW.20230117"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c09968"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202212510"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.3390\/nano10071403"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.4103\/1735-5362.235156"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.31069\/japsr.v3i3.2"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1007\/s00289-021-03761-3"},{"key":"ref82\/cit82","doi-asserted-by":"publisher","DOI":"10.3390\/pr9040621"},{"key":"ref83\/cit83","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.4c05991"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c00453","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c00453","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T08:29:21Z","timestamp":1746606561000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.5c00453"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,24]]},"references-count":83,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2025,5,7]]}},"alternative-id":["10.1021\/acsami.5c00453"],"URL":"https:\/\/doi.org\/10.1021\/acsami.5c00453","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,24]]}}}