{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:38:31Z","timestamp":1791308311200,"version":"4.3.1"},"reference-count":32,"publisher":"American Chemical Society (ACS)","issue":"15","license":[{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["CG21APR1005"],"award-info":[{"award-number":["CG21APR1005"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["MOH-001254-01"],"award-info":[{"award-number":["MOH-001254-01"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["MOH-001334-00"],"award-info":[{"award-number":["MOH-001334-00"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["MOH-001388-00"],"award-info":[{"award-number":["MOH-001388-00"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["MOH-001500-00"],"award-info":[{"award-number":["MOH-001500-00"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["MOH-001609-00"],"award-info":[{"award-number":["MOH-001609-00"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001459","name":"Ministry of Education - Singapore","doi-asserted-by":"publisher","award":["MOE-000387-00"],"award-info":[{"award-number":["MOE-000387-00"]}],"id":[{"id":"10.13039\/501100001459","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001381","name":"National Research Foundation Singapore","doi-asserted-by":"publisher","award":["NRF-000352-00"],"award-info":[{"award-number":["NRF-000352-00"]}],"id":[{"id":"10.13039\/501100001381","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001352","name":"National University of Singapore","doi-asserted-by":"publisher","award":["23-0173- A0001"],"award-info":[{"award-number":["23-0173- A0001"]}],"id":[{"id":"10.13039\/501100001352","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001352","name":"National University of Singapore","doi-asserted-by":"publisher","award":["NUHSRO\/2020\/133\/Startup\/08"],"award-info":[{"award-number":["NUHSRO\/2020\/133\/Startup\/08"]}],"id":[{"id":"10.13039\/501100001352","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001352","name":"National University of Singapore","doi-asserted-by":"publisher","award":["NUHSRO\/2021\/034\/TRP\/09\/Nanomedicine"],"award-info":[{"award-number":["NUHSRO\/2021\/034\/TRP\/09\/Nanomedicine"]}],"id":[{"id":"10.13039\/501100001352","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001352","name":"National University of Singapore","doi-asserted-by":"publisher","award":["NUHSRO\/2021\/097\/Startup\/13"],"award-info":[{"award-number":["NUHSRO\/2021\/097\/Startup\/13"]}],"id":[{"id":"10.13039\/501100001352","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001352","name":"National University of Singapore","doi-asserted-by":"publisher","award":["NUHSRO\/2023\/008\/NUSMed\/TCE\/LOA"],"award-info":[{"award-number":["NUHSRO\/2023\/008\/NUSMed\/TCE\/LOA"]}],"id":[{"id":"10.13039\/501100001352","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Scientific Research Foundation of State Key Laboratory of Vaccines for Infectious Disease, Xiang?An Biomedicine Laboratory","award":["2023XAKJ0101023"],"award-info":[{"award-number":["2023XAKJ0101023"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2025,4,16]]},"DOI":"10.1021\/acsami.5c01451","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T15:19:14Z","timestamp":1743779954000},"page":"22384-22393","source":"Crossref","is-referenced-by-count":5,"title":["Molecular Imaging of B7\u2013H3\u2013Targeting Bispecific T Cell\u2013Engaging Antibody MGD009 in Glioblastoma Models"],"prefix":"10.1021","volume":"17","author":[{"given":"Peifei","family":"Liu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang\u2019An Biomedicine Laboratory, School of Public Health","place":["Xiamen, China"]},{"name":"Xiamen University","place":["Xiamen, China"]},{"name":"Department of Diagnostic Radiology, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]},{"name":"Theranostics Center of Excellence (TCE), Yong Loo Lin School of Medicine, National University of Singapore, 11 Biopolis Way, Helios, Singapore 138667, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haizhen","family":"Ding","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang\u2019An Biomedicine Laboratory, School of Public Health","place":["Xiamen, China"]},{"name":"Xiamen University","place":["Xiamen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubing","family":"Jia","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang\u2019An Biomedicine Laboratory, School of Public Health","place":["Xiamen, China"]},{"name":"Xiamen University","place":["Xiamen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhen","family":"Pang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang\u2019An Biomedicine Laboratory, School of Public Health","place":["Xiamen, China"]},{"name":"Xiamen University","place":["Xiamen, China"]},{"name":"Department of Diagnostic Radiology, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]},{"name":"Theranostics Center of Excellence (TCE), Yong Loo Lin School of Medicine, National University of Singapore, 11 Biopolis Way, Helios, Singapore 138667, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuicui","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]},{"name":"Theranostics Center of Excellence (TCE), Yong Loo Lin School of Medicine, National University of Singapore, 11 Biopolis Way, Helios, Singapore 138667, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianzhi","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]},{"name":"Theranostics Center of Excellence (TCE), Yong Loo Lin School of Medicine, National University of Singapore, 11 Biopolis Way, Helios, Singapore 138667, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loren","family":"Skudder-Hill","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]},{"name":"Theranostics Center of Excellence (TCE), Yong Loo Lin School of Medicine, National University of Singapore, 11 Biopolis Way, Helios, Singapore 138667, Singapore"},{"name":"Clinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyan","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang\u2019An Biomedicine Laboratory, School of Public Health","place":["Xiamen, China"]},{"name":"Xiamen University","place":["Xiamen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6699-2300","authenticated-orcid":true,"given":"Hongmin","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang\u2019An Biomedicine Laboratory, School of Public Health","place":["Xiamen, China"]},{"name":"Xiamen University","place":["Xiamen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobin","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]},{"name":"Theranostics Center of Excellence (TCE), Yong Loo Lin School of Medicine, National University of Singapore, 11 Biopolis Way, Helios, Singapore 138667, Singapore"},{"name":"Department of Nuclear Medicine, Beijing Tiantan Hospital, Capital Medical University, Nan Si Huan Xi Lu 119, Fengtai District, Beijing 100070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9622-0870","authenticated-orcid":true,"given":"Xiaoyuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]},{"name":"Theranostics Center of Excellence (TCE), Yong Loo Lin School of Medicine, National University of Singapore, 11 Biopolis Way, Helios, Singapore 138667, Singapore"},{"name":"Clinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]},{"name":"Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6948-1813","authenticated-orcid":true,"given":"Jingjing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]},{"name":"Theranostics Center of Excellence (TCE), Yong Loo Lin School of Medicine, National University of Singapore, 11 Biopolis Way, Helios, Singapore 138667, Singapore"},{"name":"Clinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]},{"name":"National University of Singapore","place":["Singapore, Singapore"]},{"name":"Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine","place":["Singapore, Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,4,4]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-019-0220-2"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(09)70025-7"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043330"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2314390"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.34.15_suppl.2014"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2020.1024"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1093\/oncolo\/oyad321"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.4c07850"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c12217"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-22-0201"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-024-04564-y"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2006.05.012"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-9-463"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-1068"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2010.95"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2011.09.012"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.27566"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2012.1158"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S53565"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2018.1461304"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.omto.2019.07.002"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-012-1021-2"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.3390\/life12020157"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-015-2655-6"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(06)70665-9"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-019-04007-y"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-024-02875-1"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202001879"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-17-0657"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2020-000548"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.7150\/thno.25575"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/mp500323d"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c01451","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c01451","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T08:43:18Z","timestamp":1744792998000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.5c01451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,4]]},"references-count":32,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2025,4,16]]}},"alternative-id":["10.1021\/acsami.5c01451"],"URL":"https:\/\/doi.org\/10.1021\/acsami.5c01451","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,4]]}}}