{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:19:57Z","timestamp":1791821997048,"version":"4.3.4"},"reference-count":46,"publisher":"American Chemical Society (ACS)","issue":"17","license":[{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100017679","name":"Collaborative Innovation Project of Colleges and Universities of Anhui Province","doi-asserted-by":"publisher","award":["GXXT-2019-042"],"award-info":[{"award-number":["GXXT-2019-042"]}],"id":[{"id":"10.13039\/501100017679","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2025,4,30]]},"DOI":"10.1021\/acsami.5c02796","type":"journal-article","created":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T15:34:16Z","timestamp":1744817656000},"page":"25071-25082","source":"Crossref","is-referenced-by-count":5,"title":["Targeting Liver Fibrosis with Nanoparticle Technology: The Dual-Drug Strategy for Hepatic Stellate Cell Activation Inhibition"],"prefix":"10.1021","volume":"17","author":[{"given":"Panyi","family":"Hu","sequence":"first","affiliation":[{"name":"Department of General Surgery","place":["Hefei, People\u2019s Republic of China"]},{"name":"The First Affiliated Hospital of Anhui Medical University","place":["Hefei, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Su","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Biotherapy, Huaxi MR Research Center (HMRRC), Frontiers Science Center for Disease-Related Molecular Network, West China Hospital of Sichuan University","place":["Chengdu, People\u2019s Republic of China"]},{"name":"Sichuan University","place":["Chengdu, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongchao","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Biotherapy, Huaxi MR Research Center (HMRRC), Frontiers Science Center for Disease-Related Molecular Network, West China Hospital of Sichuan University","place":["Chengdu, People\u2019s Republic of China"]},{"name":"Sichuan University","place":["Chengdu, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongqiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of General Surgery","place":["Hefei, People\u2019s Republic of China"]},{"name":"The First Affiliated Hospital of Anhui Medical University","place":["Hefei, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2294-3945","authenticated-orcid":true,"given":"Xiaohe","family":"Tian","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Biotherapy, Huaxi MR Research Center (HMRRC), Frontiers Science Center for Disease-Related Molecular Network, West China Hospital of Sichuan University","place":["Chengdu, People\u2019s Republic of China"]},{"name":"Sichuan University","place":["Chengdu, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3145-3745","authenticated-orcid":true,"given":"Yeben","family":"Qian","sequence":"additional","affiliation":[{"name":"Department of General Surgery","place":["Hefei, People\u2019s Republic of China"]},{"name":"The First Affiliated Hospital of Anhui Medical University","place":["Hefei, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,4,16]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2019.05.007"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-022-01636-x"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31608"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2020.100312"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.7150\/thno.71400"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.4c15494"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.2c19269"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.3c11046"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.02.091"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2016.92"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2009.115"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1111\/cbdd.14421"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202310443"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.4c00249"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c04556"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.129124"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2024.05.003"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.04.002"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2024.06.047"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2020.04.081"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.7150\/thno.30418"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c07796"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.04.022"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.3c12776"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202310875"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-020-00645-y"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-022-01554-y"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1124\/pr.58.3.10"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.03.015"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.5b00448"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2019.115398"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2022.09.017"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.06.012"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155465"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201903138"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.30487"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.3390\/molecules20011277"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2021.09.176"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.938645"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.042127"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32204"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2022.02.008"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1039\/D0FO00396D"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202308477"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.134526"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.07.028"}],"container-title":["ACS Applied Materials &amp; Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c02796","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c02796","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T08:12:45Z","timestamp":1746000765000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.5c02796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,16]]},"references-count":46,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2025,4,30]]}},"alternative-id":["10.1021\/acsami.5c02796"],"URL":"https:\/\/doi.org\/10.1021\/acsami.5c02796","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,16]]}}}