{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:57:35Z","timestamp":1787000255363,"version":"build-2736575974"},"reference-count":73,"publisher":"American Chemical Society (ACS)","issue":"36","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci?n y Universidades","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011033","name":"Agencia Estatal de Investigaci?n","doi-asserted-by":"publisher","award":["PID2019-111126RB-100"],"award-info":[{"award-number":["PID2019-111126RB-100"]}],"id":[{"id":"10.13039\/501100011033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011033","name":"Agencia Estatal de Investigaci?n","doi-asserted-by":"publisher","award":["PID2022-142440NB-I00"],"award-info":[{"award-number":["PID2022-142440NB-I00"]}],"id":[{"id":"10.13039\/501100011033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011033","name":"Agencia Estatal de Investigaci?n","doi-asserted-by":"publisher","award":["RED2022-134287-T"],"award-info":[{"award-number":["RED2022-134287-T"]}],"id":[{"id":"10.13039\/501100011033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom?a y Competitividad","doi-asserted-by":"publisher","award":["RED2022-134287-T"],"award-info":[{"award-number":["RED2022-134287-T"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010801","name":"Xunta de Galicia","doi-asserted-by":"publisher","award":["ED431C 2021\/21"],"award-info":[{"award-number":["ED431C 2021\/21"]}],"id":[{"id":"10.13039\/501100010801","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010801","name":"Xunta de Galicia","doi-asserted-by":"publisher","award":["ED431C 2025\/15"],"award-info":[{"award-number":["ED431C 2025\/15"]}],"id":[{"id":"10.13039\/501100010801","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010801","name":"Xunta de Galicia","doi-asserted-by":"publisher","award":["ED431G 2023\/03"],"award-info":[{"award-number":["ED431G 2023\/03"]}],"id":[{"id":"10.13039\/501100010801","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2025,9,10]]},"DOI":"10.1021\/acsami.5c05264","type":"journal-article","created":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:00:17Z","timestamp":1756382417000},"page":"50191-50202","source":"Crossref","is-referenced-by-count":6,"title":["Self-Assembling Cyclic Peptide Nanotubes for the Delivery of Doxorubicin into Drug-Resistant Cancer Cells"],"prefix":"10.1021","volume":"17","author":[{"given":"Marcos","family":"Vilela-Picos","sequence":"first","affiliation":[{"name":"Centro Singular de Investigaci\u00f3n en Qu\u00edmica Biol\u00f3xica e Materiais Moleculares (CiQUS), Departamento de Qu\u00edmica Org\u00e1nica","place":["Santiago de Compostela, Spain"]},{"name":"Universidade de Santiago de Compostela","place":["Santiago de Compostela, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Gonz\u00e1lez-Freire","sequence":"additional","affiliation":[{"name":"Centro Singular de Investigaci\u00f3n en Qu\u00edmica Biol\u00f3xica e Materiais Moleculares (CiQUS), Departamento de Qu\u00edmica Org\u00e1nica","place":["Santiago de Compostela, Spain"]},{"name":"Universidade de Santiago de Compostela","place":["Santiago de Compostela, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Novelli","sequence":"additional","affiliation":[{"name":"Centro Singular de Investigaci\u00f3n en Qu\u00edmica Biol\u00f3xica e Materiais Moleculares (CiQUS), Departamento de Qu\u00edmica Org\u00e1nica","place":["Santiago de Compostela, Spain"]},{"name":"Universidade de Santiago de Compostela","place":["Santiago de Compostela, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4570-7707","authenticated-orcid":true,"given":"Yeray","family":"Folgar-Came\u00e1n","sequence":"additional","affiliation":[{"name":"Centro Singular de Investigaci\u00f3n en Qu\u00edmica Biol\u00f3xica e Materiais Moleculares (CiQUS), Departamento de Qu\u00edmica Org\u00e1nica","place":["Santiago de Compostela, Spain"]},{"name":"Universidade de Santiago de Compostela","place":["Santiago de Compostela, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5523-1979","authenticated-orcid":true,"given":"Jos\u00e9","family":"Brea","sequence":"additional","affiliation":[{"name":"Centro Singular de Investigaci\u00f3n en Medicina Molecular e Enfermidades Cr\u00f3nicas (CiMUS), Departamento de Farmacolog\u00eda, Farmacia y Tecnolog\u00eda Farmac\u00e9utica. Facultad de Farmacia","place":["Santiago de Compostela, Spain"]},{"name":"Universidade de Santiago de Compostela","place":["Santiago de Compostela, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Amor\u00edn","sequence":"additional","affiliation":[{"name":"Centro Singular de Investigaci\u00f3n en Qu\u00edmica Biol\u00f3xica e Materiais Moleculares (CiQUS), Departamento de Qu\u00edmica Org\u00e1nica","place":["Santiago de Compostela, Spain"]},{"name":"Universidade de Santiago de Compostela","place":["Santiago de Compostela, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5842-7504","authenticated-orcid":true,"given":"Juan R.","family":"Granja","sequence":"additional","affiliation":[{"name":"Centro Singular de Investigaci\u00f3n en Qu\u00edmica Biol\u00f3xica e Materiais Moleculares (CiQUS), Departamento de Qu\u00edmica Org\u00e1nica","place":["Santiago de Compostela, Spain"]},{"name":"Universidade de Santiago de Compostela","place":["Santiago de Compostela, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,8,28]]},"reference":[{"key":"ref1\/cit1","volume-title":"World Cancer Report: Cancer research for cancer prevention","author":"Wild C. P.","year":"2020"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2022.02.007"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1730-1"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/nrc706"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/nrd4572"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-020-0306-5"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2022.109484"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2016.29"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2023.115377"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.819563"},{"key":"ref11\/cit11","first-page":"6132","volume":"62","author":"Ran S.","year":"2002","journal-title":"Cancer Res."},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1007\/s10863-020-09846-4"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbcan.2015.08.003"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2015.122"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1039\/D0NP00019A"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-020-00269-6"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2007.387"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1529"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1527"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.202300258"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2024.01.023"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/C7OB00351J"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c01291"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.2174\/1568026614666141215143431"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/ar400061d"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/369301a0"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/35086601"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.8.3302-3310.2005"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202004127"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1039\/b902455g"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2021.183729"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1039\/C6CS00898D"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-024-02209-z"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-022-00615-z"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/mp100274f"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1039\/C2CP42038D"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1039\/C5NR06804E"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1166\/jbn.2014.1724"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201403130"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201916111"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2021.119527"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1039\/c3cc44508a"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201806483"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b20810"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00090"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200802651"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1088\/2050-6120\/4\/3\/034010"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1007\/s12154-009-0027-5"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.2478\/s11534-011-0096-2"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1101\/pdb.prot095505"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/ci960402j"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2089"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1021\/bm800657e"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1039\/C4PY00259H"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/bc00024a015"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1021\/cr100048w"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1039\/C5PY00168D"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1039\/C4CC05008H"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1039\/D3SC03930G"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b10582"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1021\/jp4003559"},{"key":"ref62\/cit62","doi-asserted-by":"crossref","unstructured":"Krimm, S.; Bandekar, J.\n                      Advances in Protein Chemistry\n                      . Anfinsen, C. B.; Edsall, J. T.; Richards, F. M., Eds. Elsevier: Amsterdam, 1986; Vol. 38, pp 181\u2013364.","DOI":"10.1016\/S0065-3233(08)60528-8"},{"key":"ref63\/cit63","first-page":"3147","volume":"35","author":"Com\u015fa \u015e.","year":"2015","journal-title":"Anticancer Res."},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djv073"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1179\/joc.2006.18.1.66"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-010-9747-1"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1023\/A:1012875105006"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1007\/s00280-019-03863-w"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(85)90251-5"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0035949"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.78.081307.110540"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-021-00858-8"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00521K"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c05264","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c05264","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T08:14:05Z","timestamp":1757492045000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.5c05264"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,28]]},"references-count":73,"journal-issue":{"issue":"36","published-print":{"date-parts":[[2025,9,10]]}},"alternative-id":["10.1021\/acsami.5c05264"],"URL":"https:\/\/doi.org\/10.1021\/acsami.5c05264","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,28]]}}}