{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T12:59:09Z","timestamp":1787921949255,"version":"build-2784847793"},"reference-count":54,"publisher":"American Chemical Society (ACS)","issue":"19","license":[{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01CA260847"],"award-info":[{"award-number":["R01CA260847"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01NS115571"],"award-info":[{"award-number":["R01NS115571"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01NS122768-01"],"award-info":[{"award-number":["R01NS122768-01"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["2T32GM15538-10"],"award-info":[{"award-number":["2T32GM15538-10"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2025,5,14]]},"DOI":"10.1021\/acsami.5c05524","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T13:31:13Z","timestamp":1746451873000},"page":"28000-28011","source":"Crossref","is-referenced-by-count":3,"title":["Alkaline Phosphatase-Targeted, Gadolinium-Labeled Nanoparticles for Enhanced Multimodal Imaging of Liver Cancer"],"prefix":"10.1021","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9349-5652","authenticated-orcid":true,"given":"Minrui","family":"Luo","sequence":"first","affiliation":[{"name":"Departments of Chemistry, Molecular Biosciences, Neurobiology, and Radiology","place":["Evanston, United States"]},{"name":"Northwestern University","place":["Evanston, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew D.","family":"Bailey","sequence":"additional","affiliation":[{"name":"Departments of Chemistry, Molecular Biosciences, Neurobiology, and Radiology","place":["Evanston, United States"]},{"name":"Northwestern University","place":["Evanston, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Departments of Chemistry, Molecular Biosciences, Neurobiology, and Radiology","place":["Evanston, United States"]},{"name":"Northwestern University","place":["Evanston, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6992-2358","authenticated-orcid":true,"given":"Yiqing","family":"Lei","sequence":"additional","affiliation":[{"name":"Departments of Chemistry, Molecular Biosciences, Neurobiology, and Radiology","place":["Evanston, United States"]},{"name":"Northwestern University","place":["Evanston, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6202-1155","authenticated-orcid":true,"given":"Thomas J.","family":"Meade","sequence":"additional","affiliation":[{"name":"Departments of Chemistry, Molecular Biosciences, Neurobiology, and Radiology","place":["Evanston, United States"]},{"name":"Northwestern University","place":["Evanston, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,5,5]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-11-0643"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a021535"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1159\/000509424"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.09.011"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbcan.2019.188314"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.2147\/JHC.S268288"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30034-6"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1186\/s41747-021-00250-0"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14163997"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c07377"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1039\/C7SC02217D"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v13.i11.1688"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2022.214567"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.1022"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/adtp.202100219"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.5b00652"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b03482"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrrev.2015.02.002"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1260\/2040-2295.4.1.23"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3390\/ma13112586"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnmrs.2006.03.003"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.0c02487"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.8b00504"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.2c00649"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b07252"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1039\/C5CC06565H"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/nn5070953"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.9b00669"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S140772"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcc.6b08362"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1039\/C4MT00340C"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/la025795x"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.6b03378"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c11678"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.6b00389"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.6b00599"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/cr500314d"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1166\/jbn.2016.2173"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.micromeso.2018.05.022"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/cr9003538"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms1042"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/jp061667w"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/ac0702084"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c00568"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1002\/cmmi.1565"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.3c03639"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.4653"},{"key":"ref49\/cit49","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4939-6676-9","volume-title":"Scanning Electron Microscopy and X-Ray Microanalysis","author":"Goldstein J.","year":"2018"},{"key":"ref50\/cit50","unstructured":"NIST X-Ray Form Factor, Atten. Scatt. Tables Form\nPage. https:\/\/physics.nist.gov\/PhysRefData\/FFast\/html\/form.html.\n(accessed April 23, 2025)."},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c07131"},{"key":"ref52\/cit52","doi-asserted-by":"crossref","DOI":"10.1007\/978-0-387-76501-3","volume-title":"Transmission Electron Microscopy: A Textbook for Materials Science","author":"Williams D. B.","year":"2009"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2089"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2007.304"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c05524","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c05524","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T08:49:45Z","timestamp":1747212585000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.5c05524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,5]]},"references-count":54,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2025,5,14]]}},"alternative-id":["10.1021\/acsami.5c05524"],"URL":"https:\/\/doi.org\/10.1021\/acsami.5c05524","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,5]]}}}