{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:35:19Z","timestamp":1792024519879,"version":"4.4.0"},"reference-count":38,"publisher":"American Chemical Society (ACS)","issue":"34","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22305177"],"award-info":[{"award-number":["22305177"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22335005"],"award-info":[{"award-number":["22335005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22475154"],"award-info":[{"award-number":["22475154"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52222306"],"award-info":[{"award-number":["52222306"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Innovation Program of Shanghai Municipal Education Commission","award":["2023ZKZD28"],"award-info":[{"award-number":["2023ZKZD28"]}]},{"name":"international scientific collaboration fund of Science and Technology Commission of Shanghai Municipality","award":["23520710900"],"award-info":[{"award-number":["23520710900"]}]},{"DOI":"10.13039\/501100013105","name":"Shanghai Rising-Star Program","doi-asserted-by":"crossref","award":["Sailing, 23YF1433000"],"award-info":[{"award-number":["Sailing, 23YF1433000"]}],"id":[{"id":"10.13039\/501100013105","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2025,8,27]]},"DOI":"10.1021\/acsami.5c11373","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T05:59:33Z","timestamp":1755151173000},"page":"48017-48028","source":"Crossref","is-referenced-by-count":9,"title":["Ultrasound-Driven Cu-Nanobots for Tumor Deep Penetration and Induction of Cuproptosis in Prostate Cancer Therapy"],"prefix":"10.1021","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8089-5848","authenticated-orcid":true,"given":"Jiaxi","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Polymeric Materials, School of Materials Science and Engineering, Tongji University, 4800 Caoan Road, Shanghai 201804, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6900-9693","authenticated-orcid":true,"given":"Mingchen","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Polymeric Materials, School of Materials Science and Engineering, Tongji University, 4800 Caoan Road, Shanghai 201804, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8236-5117","authenticated-orcid":true,"given":"Wei","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Polymeric Materials, School of Materials Science and Engineering, Tongji University, 4800 Caoan Road, Shanghai 201804, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1641-5521","authenticated-orcid":true,"given":"Ran","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Polymeric Materials, School of Materials Science and Engineering, Tongji University, 4800 Caoan Road, Shanghai 201804, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shangpeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Polymeric Materials, School of Materials Science and Engineering, Tongji University, 4800 Caoan Road, Shanghai 201804, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3025-8331","authenticated-orcid":true,"given":"Min","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics, Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People\u2019s Hospital, School of Medicine","place":["Shanghai, China"]},{"name":"Tongji University","place":["Shanghai, China"]},{"name":"School of Materials Science and Engineering","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1889-5669","authenticated-orcid":true,"given":"Jianzhong","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Polymeric Materials, School of Materials Science and Engineering, Tongji University, 4800 Caoan Road, Shanghai 201804, China"},{"name":"Department of Gynaecology and Obstetrics, Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People\u2019s Hospital, School of Medicine","place":["Shanghai, China"]},{"name":"Tongji University","place":["Shanghai, China"]},{"name":"School of Materials Science and Engineering","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4199-0082","authenticated-orcid":true,"given":"Zhen","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Polymeric Materials, School of Materials Science and Engineering, Tongji University, 4800 Caoan Road, Shanghai 201804, China"},{"name":"Department of Gynaecology and Obstetrics, Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People\u2019s Hospital, School of Medicine","place":["Shanghai, China"]},{"name":"Tongji University","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)00651-2"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-020-00243-0"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.06.001"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2010.136"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00544-0"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-018-0007-1"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2890"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202212267"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202404971"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202409066"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202406602"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adk3201"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1126\/science.abf0529"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-024-00876-0"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-022-01014-x"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-024-01784-1"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-022-01229-y"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-019-0566-2"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1522080113"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21858-1"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202401304"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c00974"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-51620-2"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.xinn.2023.100421"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202102265"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-018-0222-9"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201403621"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202306301"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-49217-w"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202006175"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2007.451"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202212866"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/nn301312z"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.6b01344"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201713082"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1126\/science.1237265"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10855"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b13882"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c11373","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c11373","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T08:12:46Z","timestamp":1756282366000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.5c11373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,14]]},"references-count":38,"journal-issue":{"issue":"34","published-print":{"date-parts":[[2025,8,27]]}},"alternative-id":["10.1021\/acsami.5c11373"],"URL":"https:\/\/doi.org\/10.1021\/acsami.5c11373","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,14]]}}}