{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T23:43:38Z","timestamp":1793317418580,"version":"4.5.0"},"reference-count":69,"publisher":"American Chemical Society (ACS)","issue":"43","license":[{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100000770","name":"University of Manchester","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000770","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2025,10,29]]},"DOI":"10.1021\/acsami.5c11562","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T19:15:55Z","timestamp":1760555755000},"page":"59067-59081","source":"Crossref","is-referenced-by-count":3,"title":["Antioxidant Poly(propylene sulfide) Nanoparticles Ameliorate Ischemia-Reperfusion Injury and Improve Porcine Kidney Function Post-Transplantation"],"prefix":"10.1021","volume":"17","author":[{"given":"John P.","family":"Stone","sequence":"first","affiliation":[{"name":"The Pebble Institute, Beech Court, Manchester SK9 4LD, U.K."},{"name":"Pebble Biotechnology Laboratories, Beech Court, Manchester SK9 4LD, U.K."},{"name":"Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre","place":["Manchester, United Kingdom"]},{"name":"University of Manchester","place":["Manchester, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"d\u2019Arcy","sequence":"additional","affiliation":[{"name":"Laboratory of Polymers and Biomaterials","place":["Genova, Italy"]},{"name":"Istituto Italiano di Tecnologia","place":["Genova, Italy"]},{"name":"Chemical Engineering, School for the Engineering of Matter, Transport, and Energy","place":["Tempe, United States"]},{"name":"Arizona State University","place":["Tempe, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbey","family":"Geraghty","sequence":"additional","affiliation":[{"name":"The Pebble Institute, Beech Court, Manchester SK9 4LD, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kavit R.","family":"Amin","sequence":"additional","affiliation":[{"name":"The Pebble Institute, Beech Court, Manchester SK9 4LD, U.K."},{"name":"Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre","place":["Manchester, United Kingdom"]},{"name":"University of Manchester","place":["Manchester, United Kingdom"]},{"name":"Department of Plastic Surgery & Burns, Wythenshawe Hospital, Manchester Academic Health Science Centre","place":["Manchester, U.K."]},{"name":"Manchester University NHS Foundation Trust","place":["Manchester, U.K."]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matilde","family":"Ghibaudi","sequence":"additional","affiliation":[{"name":"Laboratory of Polymers and Biomaterials","place":["Genova, Italy"]},{"name":"Istituto Italiano di Tecnologia","place":["Genova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7681-6442","authenticated-orcid":true,"given":"Nora","family":"Francini","sequence":"additional","affiliation":[{"name":"Laboratory of Polymers and Biomaterials","place":["Genova, Italy"]},{"name":"Istituto Italiano di Tecnologia","place":["Genova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angeles","family":"Montero-Fernandez","sequence":"additional","affiliation":[{"name":"Department of Pathology","place":["Manchester, U.K."]},{"name":"Manchester Foundation Trust","place":["Manchester, U.K."]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilan","family":"Dabare","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Transplantation","place":["Birmingham, U.K."]},{"name":"University Hospitals Birmingham NHS Foundation Trust","place":["Birmingham, U.K."]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Ogliastro","sequence":"additional","affiliation":[{"name":"Laboratory of Polymers and Biomaterials","place":["Genova, Italy"]},{"name":"Istituto Italiano di Tecnologia","place":["Genova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2397-6164","authenticated-orcid":true,"given":"Stefania","family":"Sganga","sequence":"additional","affiliation":[{"name":"Laboratory of Polymers and Biomaterials","place":["Genova, Italy"]},{"name":"Istituto Italiano di Tecnologia","place":["Genova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Coradello","sequence":"additional","affiliation":[{"name":"Laboratory of Polymers and Biomaterials","place":["Genova, Italy"]},{"name":"Istituto Italiano di Tecnologia","place":["Genova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia Della","family":"Rosa","sequence":"additional","affiliation":[{"name":"Laboratory of Polymers and Biomaterials","place":["Genova, Italy"]},{"name":"Istituto Italiano di Tecnologia","place":["Genova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo","family":"Bramhall","sequence":"additional","affiliation":[{"name":"Immunology Research Unit","place":["London, U.K."]},{"name":"GSK","place":["London, U.K."]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Galwey","sequence":"additional","affiliation":[{"name":"Biostatistics","place":["London, U.K."]},{"name":"GSK","place":["London, U.K."]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marieta","family":"Ruseva","sequence":"additional","affiliation":[{"name":"Immunology Research Unit","place":["London, U.K."]},{"name":"GSK","place":["London, U.K."]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4879-3949","authenticated-orcid":true,"given":"Nicola","family":"Tirelli","sequence":"additional","affiliation":[{"name":"Laboratory of Polymers and Biomaterials","place":["Genova, Italy"]},{"name":"Istituto Italiano di Tecnologia","place":["Genova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James E.","family":"Fildes","sequence":"additional","affiliation":[{"name":"The Pebble Institute, Beech Court, Manchester SK9 4LD, U.K."},{"name":"Pebble Biotechnology Laboratories, Beech Court, Manchester SK9 4LD, U.K."},{"name":"Healthcare Technologies Institute, School of Chemical Engineering","place":["Birmingham, United Kingdom"]},{"name":"University of Birmingham","place":["Birmingham, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,10,15]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.12861\/Jrip.2015.06"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/S41423-022-00902-0"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3390\/transplantology5020006"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-021-00896-3"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/nbt806"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/S41551-017-0037"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/S41467-019-09908-1"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/S41591-020-0971-8"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2016.07.009"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000002236"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.01621"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.11921"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02376-7"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1111\/Ajt.16148"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aaa4549"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.142339"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1126\/Scitranslmed.Aam6764"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10154"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000003754"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/bc200449k"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1039\/C3py01475d"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/C3PY01475D"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.07.042"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/Jacs.2c09232"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/Acsbiomaterials.6b00804"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/Acsnano.9b04571"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/adtp.201900038"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.12.035"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2021.110387"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/macp.201200264"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00336.x"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2007.070184"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/3804979"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2006.02.025"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.15.7002"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-142-1-200501040-00110"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00583.2009"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11030501"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.9b01348"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.2c01365"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2018.05.006"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.4c22685"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioadv.2023.213537"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/macp.202300250"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b00477"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197711000-00003"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.01744.x"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1097\/Tp.0000000000003679"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13966"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1039\/D0SM01987A"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9010253"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.1992.tb05834.x"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/S0171-2985(11)80403-1"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65026-2"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3182652b7d"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201591881"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.3389\/Fimmu.2022.970938"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0604255103"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)61779-8"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.1.6.1007"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0704458"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1161\/hh1801.097034"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.060002786.x"},{"issue":"6","key":"ref64\/cit64","first-page":"1000","volume":"20","author":"Sonkar G. K.","year":"2009","journal-title":"Saudi J. Kidney Dis. Transplant."},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2017.05.013"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2020.06.027"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-11-749879"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1022380"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1182\/Blood-2018-08-868067"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c11562","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c11562","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T08:10:34Z","timestamp":1761811834000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.5c11562"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,15]]},"references-count":69,"journal-issue":{"issue":"43","published-print":{"date-parts":[[2025,10,29]]}},"alternative-id":["10.1021\/acsami.5c11562"],"URL":"https:\/\/doi.org\/10.1021\/acsami.5c11562","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,15]]}}}