{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T01:43:30Z","timestamp":1785548610225,"version":"3.56.0"},"reference-count":59,"publisher":"American Chemical Society (ACS)","issue":"52","license":[{"start":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T00:00:00Z","timestamp":1765843200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T00:00:00Z","timestamp":1765843200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T00:00:00Z","timestamp":1765843200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["310030M_204518"],"award-info":[{"award-number":["310030M_204518"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","award":["NNF22OC0075851"],"award-info":[{"award-number":["NNF22OC0075851"]}],"id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","award":["NNF23OC0081287"],"award-info":[{"award-number":["NNF23OC0081287"]}],"id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008398","name":"Villum Fonden","doi-asserted-by":"publisher","award":["40578"],"award-info":[{"award-number":["40578"]}],"id":[{"id":"10.13039\/100008398","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008398","name":"Villum Fonden","doi-asserted-by":"publisher","award":["40801"],"award-info":[{"award-number":["40801"]}],"id":[{"id":"10.13039\/100008398","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003554","name":"Lundbeck Foundation","doi-asserted-by":"publisher","award":["R453-2024-359"],"award-info":[{"award-number":["R453-2024-359"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Det Frie Forskningsr\u00e5d","award":["1127-00432B"],"award-info":[{"award-number":["1127-00432B"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2025,12,31]]},"DOI":"10.1021\/acsami.5c16748","type":"journal-article","created":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T08:43:51Z","timestamp":1765874631000},"page":"70442-70453","source":"Crossref","is-referenced-by-count":1,"title":["Polymer-Functionalized Liposomes as Universal Nanocarriers for Drug Delivery: Single Particle Insights on Size-Dependent Performance and Intracellular Behavior"],"prefix":"10.1021","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5919-3255","authenticated-orcid":true,"given":"Errika","family":"Voutyritsa","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Copenhagen, Thorvaldsensvej 40, Frederiksberg, Copenhagen 1871, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanasios","family":"Oikonomou","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Copenhagen, Thorvaldsensvej 40, Frederiksberg, Copenhagen 1871, Denmark"},{"name":"Nanoscience Centre, University of Copenhagen, Thorvaldsensvej 40, Frederiksberg, Copenhagen 1871, Denmark"},{"name":"Novo Nordisk foundation Center for Optimised Oligo Escape University of Copenhagen","place":["Copenhagen, Denmark"]},{"name":"Novo Nordisk Foundation Center for 4D Cellular Dynamics, Department of Chemistry","place":["Copenhagen, Denmark"]},{"name":"University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Bolis","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Copenhagen, Thorvaldsensvej 40, Frederiksberg, Copenhagen 1871, Denmark"},{"name":"Nanoscience Centre, University of Copenhagen, Thorvaldsensvej 40, Frederiksberg, Copenhagen 1871, Denmark"},{"name":"Novo Nordisk Foundation Center for 4D Cellular Dynamics, Department of Chemistry","place":["Copenhagen, Denmark"]},{"name":"University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasilis","family":"Papageorgiou","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Copenhagen, Thorvaldsensvej 40, Frederiksberg, Copenhagen 1871, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aikaterini Stavroula","family":"Vougiatzi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Copenhagen, Thorvaldsensvej 40, Frederiksberg, Copenhagen 1871, Denmark"},{"name":"Nanoscience Centre, University of Copenhagen, Thorvaldsensvej 40, Frederiksberg, Copenhagen 1871, Denmark"},{"name":"Novo Nordisk foundation Center for Optimised Oligo Escape University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4202-0328","authenticated-orcid":true,"given":"Nikos S.","family":"Hatzakis","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Copenhagen, Thorvaldsensvej 40, Frederiksberg, Copenhagen 1871, Denmark"},{"name":"Nanoscience Centre, University of Copenhagen, Thorvaldsensvej 40, Frederiksberg, Copenhagen 1871, Denmark"},{"name":"Novo Nordisk foundation Center for Optimised Oligo Escape University of Copenhagen","place":["Copenhagen, Denmark"]},{"name":"Novo Nordisk Foundation Center for 4D Cellular Dynamics, Department of Chemistry","place":["Copenhagen, Denmark"]},{"name":"University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,12,16]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2014.09.029"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2016.09.027"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-3659(02)00146-3"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13091365"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1186\/s11671-017-2119-4"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.02.007"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6750-2-9"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2612"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-020-00886-0"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/ja111110e"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2022.122022"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.3c02762"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c02404"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.9b00007"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.4c20191"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b22693"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2025.113015"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.02.030"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-021-00358-0"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2020.06.002"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202404510"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3298"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.03.046"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2015.10.033"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.9b01278"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1039\/C6RA08299H"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2010.03.001"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1039\/D0SM00077A"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2012.11.010"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsps.2016.05.010"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2014.06.002"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13071023"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202319248"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/374555a0"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.213"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-22562-w"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-022-00912-5"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2104624118"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-30154-5"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.10.045"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-13284-1"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1007\/s00239-014-9655-7"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.3390\/ma17020319"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics14040778"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-52539-1"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.09.034"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c08809"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.3390\/biom10091291"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.0c01563"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-025-02665-8"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-020-01018-x"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201809056"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-35637-z"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abf4398"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-33157-4"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0123562"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-61646-3"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.52.34970"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/j.media.2023.102918"}],"container-title":["ACS Applied Materials &amp; Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c16748","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c16748","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T12:40:02Z","timestamp":1768567202000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.5c16748"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,16]]},"references-count":59,"journal-issue":{"issue":"52","published-print":{"date-parts":[[2025,12,31]]}},"alternative-id":["10.1021\/acsami.5c16748"],"URL":"https:\/\/doi.org\/10.1021\/acsami.5c16748","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,16]]}}}