{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T05:02:12Z","timestamp":1787893332287,"version":"build-2784847793"},"reference-count":54,"publisher":"American Chemical Society (ACS)","issue":"6","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100011447","name":"Science and Technology Department of Henan Province","doi-asserted-by":"publisher","award":["SBGJ202402031"],"award-info":[{"award-number":["SBGJ202402031"]}],"id":[{"id":"10.13039\/501100011447","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Beijing Municipal Natural Science Foundation","award":["JQ22024"],"award-info":[{"award-number":["JQ22024"]}]},{"name":"Beijing Municipal Natural Science Foundation","award":["L232087"],"award-info":[{"award-number":["L232087"]}]},{"name":"Beijing Municipal Natural Science Foundation","award":["L256027"],"award-info":[{"award-number":["L256027"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["32271443"],"award-info":[{"award-number":["32271443"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["82472000"],"award-info":[{"award-number":["82472000"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2026,2,18]]},"DOI":"10.1021\/acsami.5c21141","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T11:34:06Z","timestamp":1770636846000},"page":"9379-9400","source":"Crossref","is-referenced-by-count":1,"title":["Ultrasound-Responsive Cerasome Nanoparticle Improves STING-Driven Immunotherapy in Triple-Negative Breast Cancer"],"prefix":"10.1021","volume":"18","author":[{"given":"Di","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Ultrasound, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"He","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiqi","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound","place":["Beijing, China"]},{"name":"Peking University Third Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenhui","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ultrasound","place":["Zhengzhou, China"]},{"name":"Affiliated Cancer Hospital of Zhengzhou University","place":["Zhengzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuantong","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiming","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasonography","place":["Shenyang, China"]},{"name":"The First Affiliated Hospital of China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Qin","sequence":"additional","affiliation":[{"name":"Key Laboratory of Cancer and Microbiome, State Key Laboratory of Molecular Oncology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Cancer and Microbiome, State Key Laboratory of Molecular Oncology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ultrasound","place":["Zhengzhou, China"]},{"name":"Affiliated Cancer Hospital of Zhengzhou University","place":["Zhengzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7155-4738","authenticated-orcid":true,"given":"Ramasamy","family":"Paulmurugan","sequence":"additional","affiliation":[{"name":"Department of Radiology","place":["Palo Alto, United States"]},{"name":"Stanford University","place":["Palo Alto, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolong","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound","place":["Beijing, China"]},{"name":"Peking University Third Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]},{"name":"Department of Ultrasonography","place":["Shenyang, China"]},{"name":"The First Affiliated Hospital of China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,2,9]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-18-1177"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-022-01341-0"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-023-01850-7"},{"key":"ref4\/cit4","unstructured":"Role of Immunotherapy in Triple-Negative\nBreast Cancer in: Journal\nof the National Comprehensive Cancer Network Volume 18 Issue 4 (2020), 2025. https:\/\/jnccn.org\/view\/journals\/jnccn\/18\/4\/article-p479.xml. (accessed April 25, 2025)."},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202108263"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202407927"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaa2630"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-020-00675-9"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-022-01251-z"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20101158"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c08613"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2214278119"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2024.05.042"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1126\/science.abb4255"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c01333"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2025.02.061"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.02.026"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.07.014"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-024-01624-2"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c02287"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.cis.2013.11.014"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.7150\/thno.36762"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202400485"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c07287"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.3c14959"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201302518"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c09948"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202300964"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.3c00603"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c21924"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-023-02195-5"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202307272"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202300854"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202007557"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.03.047"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/nn507482w"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9367845"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S321071"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.1001899"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c07297"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201503966"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1039\/C7CP00983F"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2024.150134"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.2174\/1566524023666230613140341"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.12.065"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2023.103801"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1039\/D5TB01837D"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.3109\/17435390.2010.546950"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202400149"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S543991"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c09094"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2933"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201103557"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.04.094"}],"container-title":["ACS Applied Materials &amp; Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c21141","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c21141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T13:26:06Z","timestamp":1772717166000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.5c21141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,9]]},"references-count":54,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,2,18]]}},"alternative-id":["10.1021\/acsami.5c21141"],"URL":"https:\/\/doi.org\/10.1021\/acsami.5c21141","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,9]]}}}