{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T16:39:38Z","timestamp":1793205578620,"version":"4.5.0"},"reference-count":58,"publisher":"American Chemical Society (ACS)","issue":"16","license":[{"start":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:00:00Z","timestamp":1776211200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:00:00Z","timestamp":1776211200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:00:00Z","timestamp":1776211200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30CA134274"],"award-info":[{"award-number":["P30CA134274"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R25CA186872"],"award-info":[{"award-number":["R25CA186872"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI192405"],"award-info":[{"award-number":["R01AI192405"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R35GM142752"],"award-info":[{"award-number":["R35GM142752"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2026,4,29]]},"DOI":"10.1021\/acsami.5c24500","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T08:14:04Z","timestamp":1776240844000},"page":"22679-22691","source":"Crossref","is-referenced-by-count":2,"title":["Engineered Lactoferrin Nanoparticle Coronas as a Tunable Platform for Immunomodulation and Antibacterial Function"],"prefix":"10.1021","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5885-1006","authenticated-orcid":true,"given":"Jacob R.","family":"Shaw","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine Street, Baltimore, Maryland 21201, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Yim","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine Street, Baltimore, Maryland 21201, United States"},{"name":"Nathan Schnaper Internship Program in Translational Cancer Research","place":["Baltimore, United States"]},{"name":"University of Maryland Medical Center","place":["Baltimore, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaclyn","family":"Printz","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine Street, Baltimore, Maryland 21201, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cole","family":"Vonderheid","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine Street, Baltimore, Maryland 21201, United States"},{"name":"Nathan Schnaper Internship Program in Translational Cancer Research","place":["Baltimore, United States"]},{"name":"University of Maryland Medical Center","place":["Baltimore, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirandia","family":"Szramowski","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine Street, Baltimore, Maryland 21201, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Leung","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine Street, Baltimore, Maryland 21201, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shruti","family":"Dharmaraj","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine Street, Baltimore, Maryland 21201, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanny","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine Street, Baltimore, Maryland 21201, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4440-3840","authenticated-orcid":true,"given":"Amanda G.","family":"Oglesby","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine Street, Baltimore, Maryland 21201, United States"},{"name":"Department of Microbiology and Immunology, University of Maryland School of Medicine, 685 W. Baltimore Street, Baltimore, Maryland 21201, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7857-0973","authenticated-orcid":true,"given":"Ryan M.","family":"Pearson","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine Street, Baltimore, Maryland 21201, United States"},{"name":"Nathan Schnaper Internship Program in Translational Cancer Research","place":["Baltimore, United States"]},{"name":"University of Maryland Medical Center","place":["Baltimore, United States"]},{"name":"Department of Microbiology and Immunology, University of Maryland School of Medicine, 685 W. Baltimore Street, Baltimore, Maryland 21201, United States"},{"name":"Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, 22 S. Greene Street, Baltimore, Maryland 21201, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,4,15]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201300688"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.01.043"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-023-00552-2"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-56210-4"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics14122605"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1714267114"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.07.102"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2017.11.008"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2024.05.003"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119333"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1208\/s12248-021-00645-2"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1039\/D4PM00233D"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13111841"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01438"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2008.05.015"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.134.6.4176"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1128\/iai.61.2.719-728.1993"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3390\/nano14242018"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2018.12.084"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15051362"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.6b09069"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.14.182"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2020.11.107"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajps.2024.100926"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.onano.2023.100163"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-42702-0"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10611"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1128\/iai.62.6.2628-2632.1994"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2004.tb09482.x"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.3390\/foods12010070"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpc.2010.06.005"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1039\/C0DT00714E"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/jmr.952"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/bi0204746"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics17050653"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1080\/03639040601085334"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2021.121188"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13101698"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1177\/000456328502200604"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0608582104"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.180.10.6868"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellimm.2006.08.006"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022504"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19061801"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.9b00021"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2016.07.011"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-020-0755-z"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-48838-5"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.01.030"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-81926-6"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2007.11.001"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-69745-x"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2013.06.030"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2004.05.009"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1007\/s004230000191"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1186\/cc1819"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.2002.01956.x"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-022-00792-3"}],"container-title":["ACS Applied Materials &amp; Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c24500","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c24500","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:26:49Z","timestamp":1777458409000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.5c24500"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,15]]},"references-count":58,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2026,4,29]]}},"alternative-id":["10.1021\/acsami.5c24500"],"URL":"https:\/\/doi.org\/10.1021\/acsami.5c24500","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,15]]}}}