{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T11:22:30Z","timestamp":1794050550363,"version":"4.8.0"},"reference-count":40,"publisher":"American Chemical Society (ACS)","issue":"15","license":[{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100005145","name":"Basic Research Program of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20243057"],"award-info":[{"award-number":["BK20243057"]}],"id":[{"id":"10.13039\/501100005145","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005145","name":"Basic Research Program of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20253006"],"award-info":[{"award-number":["BK20253006"]}],"id":[{"id":"10.13039\/501100005145","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["22277058"],"award-info":[{"award-number":["22277058"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["22575124"],"award-info":[{"award-number":["22575124"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["62235008"],"award-info":[{"award-number":["62235008"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["62288102"],"award-info":[{"award-number":["62288102"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2026,4,22]]},"DOI":"10.1021\/acsami.5c26298","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T14:51:41Z","timestamp":1775832701000},"page":"21592-21603","source":"Crossref","is-referenced-by-count":2,"title":["DNA-Programmed Gold Nanoparticles for Precision Delivery of a Tissue Plasminogen Activator and Thrombin Inhibition in Thrombolytic and Anticoagulant Therapy"],"prefix":"10.1021","volume":"18","author":[{"given":"Xinxuan","family":"Huang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Flexible Electronics & Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology, Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixuan","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Flexible Electronics & Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology, Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Wu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Flexible Electronics & Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology, Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusheng","family":"Dai","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Flexible Electronics & Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology, Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyi","family":"Su","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Flexible Electronics & Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology, Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weina","family":"Hu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Flexible Electronics & Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology, Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8157-4166","authenticated-orcid":true,"given":"Dan","family":"Zhu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Flexible Electronics & Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology, Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1030-9944","authenticated-orcid":true,"given":"Jie","family":"Chao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Flexible Electronics & Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology, Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9030-9172","authenticated-orcid":true,"given":"Lianhui","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Flexible Electronics & Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology, Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8724-7748","authenticated-orcid":true,"given":"Yu","family":"Gao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Flexible Electronics & Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology, Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,4,10]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)30427-1"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.03.013"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/nature06797"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60584-5"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.122.027238"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehad088"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2023.07.042"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2017.06.010"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2009.127"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy056"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.120297"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202314583"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2020-140385"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-024-01826-y"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2023.134341"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202109609"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202214958"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.2147\/NSA.S3707"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2024.115481"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202507954"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202001647"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/ja304118z"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c11699"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-23250-5"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201000642"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201101081"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201101718"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.108.179655"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1126\/science.adh5207"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2014.09.003"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c12327"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.952648"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01584.x"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2007.12.005"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e31819bcc9c"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c13116"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2014.10.047"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2007.02430.x"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032274"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2014.05.050"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c26298","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.5c26298","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T13:48:54Z","timestamp":1776865734000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.5c26298"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,10]]},"references-count":40,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2026,4,22]]}},"alternative-id":["10.1021\/acsami.5c26298"],"URL":"https:\/\/doi.org\/10.1021\/acsami.5c26298","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,10]]}}}