{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T16:41:27Z","timestamp":1793032887953,"version":"4.5.0"},"reference-count":53,"publisher":"American Chemical Society (ACS)","issue":"14","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100007471","name":"Applied Basic Research Foundation of Yunnan Province","doi-asserted-by":"publisher","award":["202501AZ070001-024"],"award-info":[{"award-number":["202501AZ070001-024"]}],"id":[{"id":"10.13039\/100007471","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515012294"],"award-info":[{"award-number":["2024A1515012294"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["32171314"],"award-info":[{"award-number":["32171314"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["82560842"],"award-info":[{"award-number":["82560842"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2026,4,15]]},"DOI":"10.1021\/acsami.6c03910","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T01:14:16Z","timestamp":1775092456000},"page":"20318-20333","source":"Crossref","is-referenced-by-count":6,"title":["Microneedle-Based Codelivery of\n                    <i>Platycladus orientalis<\/i>\n                    -Derived Extracellular Vesicles and Minoxidil Nanoparticles for Androgenetic Alopecia Treatment"],"prefix":"10.1021","volume":"18","author":[{"given":"Yikun","family":"Shang","sequence":"first","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]},{"name":"School of Chinese Materia Medica","place":["Kunming, China"]},{"name":"Yunnan University of Chinese Medicine","place":["Kunming, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziqiao","family":"Li","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiasen","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong\u2019e","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]},{"name":"School of Chinese Materia Medica","place":["Kunming, China"]},{"name":"Yunnan University of Chinese Medicine","place":["Kunming, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyue","family":"Li","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]},{"name":"School of Chinese Materia Medica","place":["Kunming, China"]},{"name":"Yunnan University of Chinese Medicine","place":["Kunming, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]},{"name":"School of Chinese Materia Medica","place":["Kunming, China"]},{"name":"Yunnan University of Chinese Medicine","place":["Kunming, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanting","family":"Liang","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haihong","family":"Li","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meijing","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Su","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7928-2677","authenticated-orcid":true,"given":"Yan","family":"He","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3794-8519","authenticated-orcid":true,"given":"Xin","family":"Cheng","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica","place":["Kunming, China"]},{"name":"Yunnan University of Chinese Medicine","place":["Kunming, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8713-4287","authenticated-orcid":true,"given":"Xujie","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Biomedical and Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangdong University of Technology","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,4,1]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S542000"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2024.151888"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-025-00656-9"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2021.09.009"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.18486"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2021.09.040"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2021.1945527"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2022.3180"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2021.118098"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.05.045"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.2c22814"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5c05505"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.12.040"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.02.011"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202503575"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2024.153666"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.144351"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-021-06559-x"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2022.119305"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2025.143746"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2023.120555"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2020.117590"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2025.171412"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-025-02312-w"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.5c01640"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.5c15594"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2019.111835"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.3390\/cimb46100665"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1007\/s11130-025-01431-7"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2019.03.003"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2024.02.045"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202207826"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.3390\/plants11111499"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24043748"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.crfs.2022.07.007"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3390\/life12111856"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29102288"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.202403083"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2025.145480"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-050420-025929"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.22036\/pcr.2025.488416.2592"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1039\/D3MH00717K"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5c07761"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202300250"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/la101539z"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1080\/00387010.2014.880066"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/adem.201901358"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2024.11.025"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.08.007"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2024.04.020"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202312088"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2025.113597"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2025.01.034"}],"container-title":["ACS Applied Materials &amp; Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.6c03910","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.6c03910","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T08:50:21Z","timestamp":1776243021000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.6c03910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,1]]},"references-count":53,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2026,4,15]]}},"alternative-id":["10.1021\/acsami.6c03910"],"URL":"https:\/\/doi.org\/10.1021\/acsami.6c03910","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,1]]}}}