{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T13:49:00Z","timestamp":1791985740746,"version":"4.4.0"},"reference-count":50,"publisher":"American Chemical Society (ACS)","issue":"40","license":[{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"name":"National Natural Science Foundation of China (NSFC)","award":["22272064"],"award-info":[{"award-number":["22272064"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Photoprotective materials must remain on the skin during use while permitting gentle removal afterward, creating a conflict between durable adhesion and post-use cleansing. Here, we report anisotropic dumbbell-shaped mesoporous Silica-Polydopamine Janus particles (SiO2&amp;PDA JPs) designed to balance these competing requirements at the skin interface. The hydrophilic silica domain suppresses PDA aggregation and serves as a carrier for avobenzone, whereas the PDA domain provides broadband ultraviolet shielding, radical-scavenging activity, and skin adhesion. Under continuous ultraviolet irradiation, more than 70% of avobenzone remained in the Janus system after 4 h, compared with approximately 10% for free avobenzone. Ex vivo imaging indicated that the SiO2&amp;PDA JPs were predominantly confined to the skin surface, and in vivo fluorescence imaging showed approximately 60% retention after 6 h of unrestricted mouse activity. The particles resisted water rinsing but were substantially removed by wet-towel wiping. Their adsorption at oil-water interfaces and reduction of interfacial tension further promoted emulsification-assisted removal of oily residues under gentle rubbing. In HaCaT cells, the Janus formulation reduced ultraviolet-induced reactive oxygen species accumulation, mitochondrial depolarization, and \u03b3H2AX formation. In a mouse model, it attenuated epidermal thickening and ultraviolet-associated DNA damage. These results identify anisotropic SiO2&amp;PDA JPs as an adhesive-yet-removable skin-interfacing biomaterial integrating ultraviolet-filter stabilization, radical-scavenging activity, surface retention, and practical cleansing.<\/jats:p>","DOI":"10.1021\/acsami.6c15420","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:01:51Z","timestamp":1791255711000},"page":"55645-55657","source":"Crossref","is-referenced-by-count":0,"title":["Adhesive-Yet-Removable Silica-Polydopamine Janus Particles for High-Performance Skin Photoprotection"],"prefix":"10.1021","volume":"18","author":[{"given":"Beizhe","family":"Chang","sequence":"first","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoran","family":"Jin","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Licheng","family":"Chen","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyuan","family":"Ji","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1820-3354","authenticated-orcid":true,"given":"Bingtian","family":"Zhao","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6697-409X","authenticated-orcid":true,"given":"Hang","family":"Jiang","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8532-2006","authenticated-orcid":true,"given":"Yunxing","family":"Li","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1809-4354","authenticated-orcid":true,"given":"Cheng","family":"Yang","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"issue":"7527","key":"2026101409073421600_cit1","doi-asserted-by":"publisher","first-page":"S124","DOI":"10.1038\/515S124a","article-title":"The Sunscreen Pill","volume":"515","author":"Biba","year":"2014","journal-title":"Nature"},{"issue":"9586","key":"2026101409073421600_cit2","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1016\/s0140-6736(07)60638-2","article-title":"Photoprotection","volume":"370","author":"Lautenschlager","year":"2007","journal-title":"Lancet"},{"issue":"3","key":"2026101409073421600_cit3","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1001\/jama.2019.20747 %JJAMA","article-title":"Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: a Randomized Clinical Trial","volume":"323","author":"Matta","year":"2020","journal-title":"JAMA"},{"issue":"11","key":"2026101409073421600_cit4","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1038\/s41577-019-0185-9","article-title":"Photoimmunology: How Ultraviolet Radiation Affects the Immune System","volume":"19","author":"Bernard","year":"2019","journal-title":"Nat. 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