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Benefiting from the superior atomic diffusivity and weak interfacial confinement of the liquid substrate, the as-deposited Ag nanostructures generate robust plasmonic coupling and uniformly distributed hot spots, which serve as two critical factors for achieving prominent Raman signal enhancement. Rhodamine 6G is employed as a probe molecule to systematically investigate the SERS performance of the fabricated substrates by varying the mass of silver powder and the deposition distance. Combined with finite-difference time-domain (FDTD) simulations, the results confirm that optimized deposition parameters significantly improve the Raman signal intensity, substrate uniformity, and detection reproducibility. This work provides a feasible and controllable strategy for the construction of liquid-template-assisted Ag nanostructures and establishes a reliable platform for the design and preparation of high-performance SERS sensing devices.<\/jats:p>","DOI":"10.1021\/acsami.6c16234","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:01:47Z","timestamp":1786978907000},"page":"45834-45844","source":"Crossref","is-referenced-by-count":0,"title":["LP-CVD Fabrication of Silver Films on Liquid Surfaces for Surface-Enhanced Raman Scattering Detection"],"prefix":"10.1021","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3395-7725","authenticated-orcid":true,"given":"Ziran","family":"Ye","sequence":"first","affiliation":[{"name":"Zhejiang University of Technology , , ,","place":["Hangzhou, China, 310023"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolei","family":"Hu","sequence":"additional","affiliation":[{"name":"Zhejiang University of Technology , , ,","place":["Hangzhou, China, 310023"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanhua","family":"He","sequence":"additional","affiliation":[{"name":"Zhejiang University of Technology , , ,","place":["Hangzhou, China, 310023"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaochan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Zhejiang University of Technology , , ,","place":["Hangzhou, China, 310023"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Shen","sequence":"additional","affiliation":[{"name":"Zhejiang University of Technology , , ,","place":["Hangzhou, China, 310023"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixian","family":"Xu","sequence":"additional","affiliation":[{"name":"Zhejiang University of Technology , , ,","place":["Hangzhou, China, 310023"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Zhejiang University of Technology , , ,","place":["Hangzhou, China, 310023"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaoxiang","family":"Ye","sequence":"additional","affiliation":[{"name":"Zhejiang University , , 38 Zheda Road , ,","place":["Hangzhou, China, 310027"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7885-8109","authenticated-orcid":true,"given":"Bo","family":"Yan","sequence":"additional","affiliation":[{"name":"Zhejiang University of Technology , , ,","place":["Hangzhou, China, 310023"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"issue":"6","key":"2026102812063862900_cit1","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1038\/nmat2162","article-title":"Biosensing with plasmonic nanosensors","volume":"7","author":"Anker","year":"2008","journal-title":"Nat. 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