{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T23:45:11Z","timestamp":1793922311531,"version":"4.8.0"},"reference-count":70,"publisher":"American Chemical Society (ACS)","issue":"22","license":[{"start":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T00:00:00Z","timestamp":1557100800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T00:00:00Z","timestamp":1557100800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T00:00:00Z","timestamp":1557100800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81573616"],"award-info":[{"award-number":["81573616"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81690263"],"award-info":[{"award-number":["81690263"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81773911"],"award-info":[{"award-number":["81773911"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shanghai Peak Disciplines-Integrative Medicine","award":["20150407"],"award-info":[{"award-number":["20150407"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2019,6,5]]},"DOI":"10.1021\/acsami.8b22693","type":"journal-article","created":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T14:27:17Z","timestamp":1557152837000},"page":"20304-20315","source":"Crossref","is-referenced-by-count":197,"title":["Role of Liposome Size, Surface Charge, and PEGylation on Rheumatoid Arthritis Targeting Therapy"],"prefix":"10.1021","volume":"11","author":[{"given":"Hongwei","family":"Ren","sequence":"first","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmacy, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuwei","family":"He","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmacy, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianming","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmacy, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhekang","family":"Cheng","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Minzu University of China, Beijing 100081, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhu","sequence":"additional","affiliation":[{"name":"Institute of Clinical Pharmacology, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmacy, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmacy, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinchun","family":"Xu","sequence":"additional","affiliation":[{"name":"Shanghai Xuhui Central Hospital, Shanghai 200031, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0879-5883","authenticated-orcid":true,"given":"Jianxin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmacy, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education, Shanghai 201203, China"},{"name":"Institute of Integrated Chinese and Western Medicine, Fudan University, Shanghai 200040, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2019,5,6]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01661"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1109"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2016.12.027"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.131730"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1951.03670340019005"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.12.024"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/978351"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.030759"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2008.05.010"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/573528"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.31122"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/nn500685h"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.2174\/1877912305666150616215800"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1517\/17425247.5.9.1027"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1007\/s12272-011-1109-9"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-3659(99)00248-5"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1517\/17425247.2.3.465"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2010.03.011"},{"key":"ref19\/cit19","first-page":"3752","volume":"55","author":"Dellian M.","year":"1995","journal-title":"Cancer Res."},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/mp800051m"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.2174\/138161210791920496"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1002\/art.11140"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1340"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2010.01.065"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/s0006-291x(75)80433-5"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-3659(01)00451-5"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2008.04.004"},{"key":"ref28\/cit28","volume-title":"Poly(amino acid)s: Next-Generation Coatings for Long-Circulating Liposomes","author":"Romberg B.","year":"2007"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.06.046"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2005.10.010"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1023\/a:1012248721523"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780241215"},{"key":"ref33\/cit33","first-page":"6387","volume":"46","author":"Matsumura Y.","year":"1986","journal-title":"Cancer Res."},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1186\/ar2326"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.170.9.4793"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/bi0257080"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1186\/ar3130"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/mp060072i"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2012.03.006"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.06.019"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0600997103"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(91)90385-l"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(94)90038-8"},{"key":"ref44\/cit44","first-page":"239","volume-title":"Nanoscience and Technology: A Collection of Reviews from Nature Journals","author":"Davis M. E.","year":"2010"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-02-413047"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.2217\/17435889.3.5.703"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.07.028"},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"4234","DOI":"10.4049\/jimmunol.146.12.4234","volume":"146","author":"Chonn A.","year":"1991","journal-title":"J. Immunol."},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2006.03.039"},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0169-409X(97)00131-2","volume":"32","author":"Patel H. M.","year":"1998","journal-title":"Adv. Drug Deliv. Rev."},{"key":"ref51\/cit51","first-page":"359","volume":"45","author":"Chen T.","year":"2010","journal-title":"Yao Xue Xue Bao"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2005.01.018"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-3659(03)00201-3"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1039\/c3nr05559k"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-7254.2005.00537.x"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1021\/nn101937h"},{"key":"ref57\/cit57","first-page":"3645","volume":"5","author":"Hong R. L.","year":"1999","journal-title":"Clin. Cancer Res."},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1002\/art.23072"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.12.153"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1136\/ard.62.suppl_2.ii60"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2003.009944"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1021\/mp2000742"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.1992.tb02939.x"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2007.173"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1038\/nature15373"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2016.03.035"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2018.02.001"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1186\/ar3089"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1002\/art.21719"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2015.08.025"}],"container-title":["ACS Applied Materials &amp; Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.8b22693","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T06:27:28Z","timestamp":1682576848000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.8b22693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,6]]},"references-count":70,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2019,6,5]]}},"alternative-id":["10.1021\/acsami.8b22693"],"URL":"https:\/\/doi.org\/10.1021\/acsami.8b22693","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,6]]}}}