{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T11:28:08Z","timestamp":1773055688855,"version":"3.50.1"},"reference-count":52,"publisher":"American Chemical Society (ACS)","issue":"34","license":[{"start":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T00:00:00Z","timestamp":1565136000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T00:00:00Z","timestamp":1565136000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T00:00:00Z","timestamp":1565136000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["13\/IA\/1962"],"award-info":[{"award-number":["13\/IA\/1962"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["12\/IP\/1688"],"award-info":[{"award-number":["12\/IP\/1688"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001590","name":"Health Research Board","doi-asserted-by":"publisher","award":["HRA-POR2013-412"],"award-info":[{"award-number":["HRA-POR2013-412"]}],"id":[{"id":"10.13039\/501100001590","id-type":"DOI","asserted-by":"publisher"}]},{"name":"DEBRA Ireland"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2019,8,28]]},"DOI":"10.1021\/acsami.9b13135","type":"journal-article","created":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T20:54:16Z","timestamp":1565211256000},"page":"30661-30672","source":"Crossref","is-referenced-by-count":48,"title":["Efficient and Robust Highly Branched Poly(\u03b2-amino ester)\/Minicircle <i>COL7A1<\/i> Polymeric Nanoparticles for Gene Delivery to Recessive Dystrophic Epidermolysis Bullosa Keratinocytes"],"prefix":"10.1021","volume":"11","author":[{"given":"Ming","family":"Zeng","sequence":"first","affiliation":[{"name":"Charles Institute of Dermatology, University College Dublin, Dublin D04 V1W8, Ireland"},{"name":"Department of Dermatology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatma","family":"Alshehri","sequence":"additional","affiliation":[{"name":"Charles Institute of Dermatology, University College Dublin, Dublin D04 V1W8, Ireland"},{"name":"Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dezhong","family":"Zhou","sequence":"additional","affiliation":[{"name":"Charles Institute of Dermatology, University College Dublin, Dublin D04 V1W8, Ireland"},{"name":"School of Chemical Engineering and Technology, Xi\u2019an Jiaotong University, Xi\u2019an, Shaanxi 710049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Lara-S\u00e1ez","sequence":"additional","affiliation":[{"name":"Charles Institute of Dermatology, University College Dublin, Dublin D04 V1W8, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi","family":"Wang","sequence":"additional","affiliation":[{"name":"Charles Institute of Dermatology, University College Dublin, Dublin D04 V1W8, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolin","family":"Li","sequence":"additional","affiliation":[{"name":"Charles Institute of Dermatology, University College Dublin, Dublin D04 V1W8, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sigen","family":"A","sequence":"additional","affiliation":[{"name":"Charles Institute of Dermatology, University College Dublin, Dublin D04 V1W8, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Xu","sequence":"additional","affiliation":[{"name":"Charles Institute of Dermatology, University College Dublin, Dublin D04 V1W8, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Charles Institute of Dermatology, University College Dublin, Dublin D04 V1W8, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5053-0611","authenticated-orcid":true,"given":"Wenxin","family":"Wang","sequence":"additional","affiliation":[{"name":"Charles Institute of Dermatology, University College Dublin, Dublin D04 V1W8, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2019,8,7]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.5582\/irdr.2017.01005"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2015.05.008"},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"20256","DOI":"10.1016\/S0021-9258(17)31984-1","volume":"269","author":"Christiano A. M.","year":"1994","journal-title":"J. Biol. Chem."},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2010.249"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12471830"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2009.10.020"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/nm1063"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.10"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12599"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2015.158"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0910501"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2015.149"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1126\/science.1083413"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2006.17.253"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3302364"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2141"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/bjp.2008.349"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0052189"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/nrg3763"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2015\/10443.5394"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2015.12.012"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2006.04.014"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/ja0015388"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200351244"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/ja034429c"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2004.11.015"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200700371"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1039\/C5CC02193F"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.5b00966"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.3390\/polym9050161"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1600102"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2016.06.014"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.6b12078"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2012.01.046"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b04098"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2013.06.001"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2006.05.024"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2010.249"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-59745-561-9_4"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/S1525-0016(03)00168-0"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.2015.996544"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1775"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/jgm.1035"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1007\/s12033-012-9535-6"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.04.016"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1021\/nn501197v"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.36033"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/nn504905q"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1039\/c2lc40176b"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2008.12.005"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201101718"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1021\/mp3004176"}],"container-title":["ACS Applied Materials &amp; Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.9b13135","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T17:57:42Z","timestamp":1681754262000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.9b13135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,7]]},"references-count":52,"journal-issue":{"issue":"34","published-print":{"date-parts":[[2019,8,28]]}},"alternative-id":["10.1021\/acsami.9b13135"],"URL":"https:\/\/doi.org\/10.1021\/acsami.9b13135","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,7]]}}}