{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T04:07:02Z","timestamp":1793419622245,"version":"4.5.0"},"reference-count":54,"publisher":"American Chemical Society (ACS)","issue":"6","license":[{"start":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T00:00:00Z","timestamp":1684368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T00:00:00Z","timestamp":1684368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T00:00:00Z","timestamp":1684368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100007937","name":"Peking University","doi-asserted-by":"publisher","award":["KYQD2021099"],"award-info":[{"award-number":["KYQD2021099"]}],"id":[{"id":"10.13039\/501100007937","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016966","name":"Bethune Charitable Foundation","doi-asserted-by":"publisher","award":["G-X-2020-1107-21"],"award-info":[{"award-number":["G-X-2020-1107-21"]}],"id":[{"id":"10.13039\/100016966","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010226","name":"Department of Education of Guangdong Province","doi-asserted-by":"publisher","award":["2022KQNCX232"],"award-info":[{"award-number":["2022KQNCX232"]}],"id":[{"id":"10.13039\/501100010226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017622","name":"Shenzhen Research and Development Program","doi-asserted-by":"publisher","award":["JCYJ20210324110214040"],"award-info":[{"award-number":["JCYJ20210324110214040"]}],"id":[{"id":"10.13039\/501100017622","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017622","name":"Shenzhen Research and Development Program","doi-asserted-by":"publisher","award":["Z2021N054"],"award-info":[{"award-number":["Z2021N054"]}],"id":[{"id":"10.13039\/501100017622","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82001319"],"award-info":[{"award-number":["82001319"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82102076"],"award-info":[{"award-number":["82102076"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82102568"],"award-info":[{"award-number":["82102568"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172432"],"award-info":[{"award-number":["82172432"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shenzhen High-level Hospital Construction Fund"},{"name":"Shenzhen Key Medical Discipline Construction","award":["SZXK023"],"award-info":[{"award-number":["SZXK023"]}]},{"name":"Shenzhen Institute of Information Technology","award":["SZIIT2022KJ063"],"award-info":[{"award-number":["SZIIT2022KJ063"]}]},{"DOI":"10.13039\/501100021171","name":"Guangdong Basic and Applied Basic Research Foundation","doi-asserted-by":"crossref","award":["2021A1515012586"],"award-info":[{"award-number":["2021A1515012586"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National and Local Joint Engineering Research Center of Orthopaedic Biomaterials","award":["XMHT20190204007"],"award-info":[{"award-number":["XMHT20190204007"]}]},{"name":"Shenzhen high-level talents","award":["11400202201020108"],"award-info":[{"award-number":["11400202201020108"]}]},{"name":"Shenzhen \u00e2??San-Ming\u00e2?\u009d Project of Medicine","award":["SZSM201612092"],"award-info":[{"award-number":["SZSM201612092"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Biomater. Sci. Eng."],"published-print":{"date-parts":[[2023,6,12]]},"DOI":"10.1021\/acsbiomaterials.2c01097","type":"journal-article","created":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T16:27:02Z","timestamp":1684427222000},"page":"3435-3444","source":"Crossref","is-referenced-by-count":21,"title":["Biomimetic Porous Magnesium Alloy Scaffolds Promote the Repair of Osteoporotic Bone Defects in Rats through Activating the Wnt\/\u03b2-Catenin Signaling Pathway"],"prefix":"10.1021","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0381-7492","authenticated-orcid":true,"given":"Yuanchao","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China"},{"name":"National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Peking University Shenzhen Hospital, Shenzhen 518036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaozhi","family":"Jia","sequence":"additional","affiliation":[{"name":"School of Intelligent Manufacturing and Equipment, Shenzhen Institute of Information Technology, Shenzhen 518172, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifei","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China"},{"name":"National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Peking University Shenzhen Hospital, Shenzhen 518036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Weng","sequence":"additional","affiliation":[{"name":"Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China"},{"name":"National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Peking University Shenzhen Hospital, Shenzhen 518036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China"},{"name":"National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Peking University Shenzhen Hospital, Shenzhen 518036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengwei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China"},{"name":"National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Peking University Shenzhen Hospital, Shenzhen 518036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Zunyi Medical University, Zunyi 563000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haotian","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China"},{"name":"National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Peking University Shenzhen Hospital, Shenzhen 518036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yixiao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China"},{"name":"National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Peking University Shenzhen Hospital, Shenzhen 518036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Peking University Shenzhen Hospital, Shenzhen 518036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2443-8408","authenticated-orcid":true,"given":"Guangyin","family":"Yuan","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University, Shanghai 200240, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China"},{"name":"National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Peking University Shenzhen Hospital, Shenzhen 518036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China"},{"name":"National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Peking University Shenzhen Hospital, Shenzhen 518036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,5,18]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13051609"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2021.05.014"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-91248-6"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-021-02772-0"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.3803\/enm.2021.1215"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2019.115071"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-021-02806-x"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1093\/bmb\/ldaa005"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.18632\/aging.103168"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2020.1787381"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.23736\/s2724-606x.20.04674-2"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2013.05.017"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/9358989"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-84526-w"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20020385"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1039\/d1tb00178g"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.110640"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.06.005"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.755260"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(82)90409-3"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20225525"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-021-02487-3"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00543.2019"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.2174\/1389201021666200611121539"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-020-3138-3"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.2147\/ijn.s181855"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2018.0019"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2015.07.042"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1007\/s00068-019-01159-5"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2072"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1916525"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOS-D-14-00018"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-75328-7"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2016.11.027"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.9b01911"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2019.03.006"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.617585"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/4941635"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2021.03.068"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-022-03364-7"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.3390\/jfb13040221"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.090806"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2020.106960"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-021-02581-6"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-022-02714-5"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.108746"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2022.109870"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-022-02949-1"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-61825-2"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2021.10321"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1186\/s10020-021-00413-0"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201901550r"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2019.06.001"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.34828"}],"container-title":["ACS Biomaterials Science &amp; Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsbiomaterials.2c01097","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsbiomaterials.2c01097","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T08:21:22Z","timestamp":1686558082000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsbiomaterials.2c01097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,18]]},"references-count":54,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6,12]]}},"alternative-id":["10.1021\/acsbiomaterials.2c01097"],"URL":"https:\/\/doi.org\/10.1021\/acsbiomaterials.2c01097","relation":{},"ISSN":["2373-9878","2373-9878"],"issn-type":[{"value":"2373-9878","type":"print"},{"value":"2373-9878","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,18]]}}}