{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T02:56:26Z","timestamp":1791860186632,"version":"4.3.4"},"reference-count":221,"publisher":"American Chemical Society (ACS)","issue":"9","license":[{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001832","name":"Radboud Universiteit","doi-asserted-by":"publisher","award":["Radboud Excellence Initiative"],"award-info":[{"award-number":["Radboud Excellence Initiative"]}],"id":[{"id":"10.13039\/501100001832","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018694","name":"HORIZON EUROPE Marie Sklodowska-Curie Actions","doi-asserted-by":"publisher","award":["101154946"],"award-info":[{"award-number":["101154946"]}],"id":[{"id":"10.13039\/100018694","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Biomater. Sci. Eng."],"published-print":{"date-parts":[[2025,9,8]]},"DOI":"10.1021\/acsbiomaterials.5c00342","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T12:05:55Z","timestamp":1755691555000},"page":"5131-5144","source":"Crossref","is-referenced-by-count":7,"title":["Toward Sex-Specific Biomaterials Innovation: A Perspective"],"prefix":"10.1021","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5802-4369","authenticated-orcid":true,"given":"Gerry L.","family":"Koons","sequence":"first","affiliation":[{"name":"Regenerative Biomaterials Research Group","place":["Nijmegen, The Netherlands"]},{"name":"Radboud University Medical Center","place":["Nijmegen, The Netherlands"]},{"name":"Computational Pathology Research Group, Research Institute for Medical Innovation","place":["Nijmegen, The Netherlands"]},{"name":"Radboud University Medical Center","place":["Nijmegen, The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-020-0204-2"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.11.030"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2020.07.021"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2019.7194"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-815767-1.00004-3"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1210\/endrev\/bnaa034"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21010296"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3390\/biom12030413"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.3390\/life14020234"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.17179\/excli2020-3210"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1186\/s13293-023-00500-3"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2013.11.008"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00217.2016"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/jor.70018"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.4161\/derm.23872"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-021-00171-z"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2016.9539"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-013-0081-6"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.24.00194"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2023.10.008"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1210\/endrev\/bnac017"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-024-00267-6"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)00457-9"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.16.00720"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-018-0716-7"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-021-00438-7"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22031114"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.37885"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.mattod.2023.01.018"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18112325"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2013.0473"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1039\/D3BM00629H"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.01184"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1007\/s10029-025-03371-2"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2021.04.008"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.121177"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-020-01692-2"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2021.04.028"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1111\/fcp.12126"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1002\/anbr.202200089"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-70178-3_2"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1111\/bph.12362"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2023.05.011"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-019-1355-0"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1088\/2515-7639\/ac90ee"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1039\/D0BM01240H"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-021-04953-1"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1115\/1.4034442"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-020-04612-x"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1002\/term.3121"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.21037\/atm-23-1724"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-022-01329-5"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.21451\/1984-3143-AR2018-0099"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering8070099"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1177\/0963689719854363"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1115\/1.4063101"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1097\/gme.0000000000001673"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abj3138"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1093\/rb\/rbz021"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202202490"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1039\/D4TB01755B"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines8110525"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2019.105409"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.3998\/ptpbio.2096"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.3390\/muscles3030024"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1186\/s13293-022-00477-5"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1756703"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000001291"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1177\/2168479018774320"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.04.014"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1038\/509282a"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-021-00806-8"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1186\/s13293-022-00420-8"},{"key":"ref74\/cit74","unstructured":"U.S. Food\nand Drug Administration.  Evaluation\nof Sex Differences in Clinical Investigations, 2025."},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-85704-8.00030-X"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1657-6"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.70817"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202001034"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.5483\/BMBRep.2018.51.4.034"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.90623"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-023-03060-w"},{"key":"ref82\/cit82","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a039156"},{"key":"ref83\/cit83","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-823937-7.00004-3"},{"key":"ref84\/cit84","doi-asserted-by":"publisher","unstructured":"The Intersection of Regenerative Medicine and Women\u2019s Health:\nProceedings of a Workshop\u2500in Brief; Beachy, S. H.; Wizemann, T. M.; Drewry, M., Eds. Washington (DC), 2025 10.17226\/29088.","DOI":"10.17226\/29088"},{"key":"ref85\/cit85","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1010525"},{"key":"ref86\/cit86","doi-asserted-by":"publisher","DOI":"10.1096\/fj.13-233395"},{"key":"ref87\/cit87","doi-asserted-by":"publisher","DOI":"10.1042\/CS20160847"},{"key":"ref88\/cit88","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.13615"},{"key":"ref89\/cit89","doi-asserted-by":"publisher","DOI":"10.1113\/EP086797"},{"key":"ref90\/cit90","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-021-01435-8"},{"key":"ref91\/cit91","doi-asserted-by":"publisher","DOI":"10.1186\/s41231-019-0050-7"},{"key":"ref92\/cit92","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-021-04070-2"},{"key":"ref93\/cit93","doi-asserted-by":"publisher","DOI":"10.1038\/sdata.2019.21"},{"key":"ref94\/cit94","doi-asserted-by":"publisher","DOI":"10.1038\/s41597-023-01969-8"},{"key":"ref95\/cit95","doi-asserted-by":"publisher","DOI":"10.1038\/srep26286"},{"key":"ref96\/cit96","doi-asserted-by":"publisher","DOI":"10.1016\/j.patter.2021.100347"},{"key":"ref97\/cit97","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2024.0067"},{"key":"ref98\/cit98","doi-asserted-by":"publisher","DOI":"10.7494\/cmms.2022.4.0799"},{"key":"ref99\/cit99","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2021.05.053"},{"key":"ref100\/cit100","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202102703"},{"key":"ref101\/cit101","doi-asserted-by":"publisher","DOI":"10.1002\/aisy.202070125"},{"key":"ref102\/cit102","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.2c00962"},{"key":"ref103\/cit103","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.02.027"},{"key":"ref104\/cit104","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2021.100165"},{"key":"ref105\/cit105","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-40459-8"},{"key":"ref106\/cit106","doi-asserted-by":"publisher","DOI":"10.1021\/acspolymersau.2c00037"},{"key":"ref107\/cit107","doi-asserted-by":"publisher","DOI":"10.3390\/app14156590"},{"key":"ref108\/cit108","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.01.018"},{"key":"ref109\/cit109","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2018.12.035"},{"key":"ref110\/cit110","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23084119"},{"key":"ref111\/cit111","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2024.103002"},{"key":"ref112\/cit112","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-bioeng-092222-030857"},{"key":"ref113\/cit113","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjco.2021.11.006"},{"key":"ref114\/cit114","doi-asserted-by":"publisher","DOI":"10.3389\/fmedt.2024.1320690"},{"key":"ref115\/cit115","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-88534-8.00030-4"},{"key":"ref116\/cit116","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-021-00381-1"},{"key":"ref117\/cit117","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-023-00306-4"},{"key":"ref118\/cit118","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-021-02821-8"},{"key":"ref119\/cit119","doi-asserted-by":"publisher","DOI":"10.1080\/13697137.2021.1951206"},{"key":"ref120\/cit120","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-023-04051-6"},{"key":"ref121\/cit121","doi-asserted-by":"publisher","DOI":"10.2196\/32683"},{"key":"ref122\/cit122","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2013.05.006"},{"key":"ref123\/cit123","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2021.05.014"},{"key":"ref124\/cit124","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.4270"},{"key":"ref125\/cit125","doi-asserted-by":"publisher","DOI":"10.3390\/biom13071136"},{"key":"ref126\/cit126","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines12081830"},{"key":"ref127\/cit127","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11247477"},{"key":"ref128\/cit128","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2023.122066"},{"key":"ref129\/cit129","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-021-00180-y"},{"key":"ref130\/cit130","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.9b04313"},{"key":"ref131\/cit131","doi-asserted-by":"publisher","DOI":"10.1177\/1357034X241293033"},{"key":"ref132\/cit132","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2023.03.004"},{"key":"ref133\/cit133","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-018-0147-9"},{"key":"ref134\/cit134","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2016.01.063"},{"key":"ref135\/cit135","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2018.00492"},{"key":"ref136\/cit136","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2018.00002"},{"key":"ref137\/cit137","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30261-4"},{"key":"ref138\/cit138","doi-asserted-by":"publisher","DOI":"10.4062\/biomolther.2018.103"},{"key":"ref139\/cit139","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2016.04.001"},{"key":"ref140\/cit140","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15061815"},{"key":"ref141\/cit141","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-020-0503-4"},{"key":"ref142\/cit142","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02279"},{"key":"ref143\/cit143","doi-asserted-by":"publisher","DOI":"10.4415\/ANN_16_02_12"},{"key":"ref144\/cit144","doi-asserted-by":"publisher","DOI":"10.1186\/s13293-020-00301-y"},{"key":"ref145\/cit145","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2021.01.025"},{"key":"ref146\/cit146","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.0c00341"},{"key":"ref147\/cit147","doi-asserted-by":"publisher","DOI":"10.1007\/s40883-022-00279-6"},{"key":"ref148\/cit148","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.4c00537"},{"key":"ref149\/cit149","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00265"},{"key":"ref150\/cit150","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-019-05040-3"},{"key":"ref151\/cit151","doi-asserted-by":"publisher","DOI":"10.1210\/er.2015-1137"},{"key":"ref152\/cit152","doi-asserted-by":"publisher","DOI":"10.1007\/s11892-018-1005-5"},{"key":"ref153\/cit153","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2020.00022"},{"key":"ref154\/cit154","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2017.08.016"},{"key":"ref155\/cit155","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-019-0112-5"},{"key":"ref156\/cit156","doi-asserted-by":"publisher","DOI":"10.1021\/acsmaterialsau.3c00073"},{"key":"ref157\/cit157","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2017.04.007"},{"key":"ref158\/cit158","doi-asserted-by":"publisher","DOI":"10.1042\/CS20160998"},{"key":"ref159\/cit159","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-019-4939-5"},{"key":"ref160\/cit160","doi-asserted-by":"publisher","DOI":"10.1557\/s43577-022-00389-0"},{"key":"ref161\/cit161","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-024-02651-w"},{"key":"ref162\/cit162","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.35158"},{"key":"ref163\/cit163","doi-asserted-by":"publisher","DOI":"10.1111\/luts.12098"},{"key":"ref164\/cit164","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-023-01485-w"},{"key":"ref165\/cit165","doi-asserted-by":"publisher","DOI":"10.30954\/2277-940X.02.2020.7"},{"key":"ref166\/cit166","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmw016"},{"key":"ref167\/cit167","doi-asserted-by":"publisher","DOI":"10.1002\/app.46068"},{"key":"ref168\/cit168","doi-asserted-by":"publisher","DOI":"10.1016\/j.engreg.2021.11.006"},{"key":"ref169\/cit169","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-019-02402-1"},{"key":"ref170\/cit170","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.11.023"},{"key":"ref171\/cit171","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.122.062049"},{"key":"ref172\/cit172","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1215958"},{"key":"ref173\/cit173","doi-asserted-by":"publisher","DOI":"10.1016\/j.cobeha.2018.05.007"},{"key":"ref174\/cit174","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2018.11.008"},{"key":"ref175\/cit175","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201700905"},{"key":"ref176\/cit176","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2021.10.003"},{"key":"ref177\/cit177","doi-asserted-by":"publisher","DOI":"10.1039\/D3MA00736G"},{"key":"ref178\/cit178","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-024-03734-z"},{"key":"ref179\/cit179","doi-asserted-by":"publisher","DOI":"10.3389\/fmats.2023.1328904"},{"key":"ref180\/cit180","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aam8645"},{"key":"ref181\/cit181","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2017.1624"},{"key":"ref182\/cit182","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00684-X"},{"key":"ref183\/cit183","doi-asserted-by":"publisher","DOI":"10.1177\/21649561211042583"},{"key":"ref184\/cit184","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2019.8067"},{"key":"ref185\/cit185","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2022.0488"},{"key":"ref186\/cit186","doi-asserted-by":"publisher","DOI":"10.1016\/j.medj.2022.04.010"},{"key":"ref187\/cit187","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.25878"},{"key":"ref188\/cit188","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0000000000005841"},{"key":"ref189\/cit189","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2024.1289592"},{"key":"ref190\/cit190","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2025.05.002"},{"key":"ref191\/cit191","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2024.102728"},{"key":"ref192\/cit192","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-08-102967-1.00013-X"},{"key":"ref193\/cit193","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2021-007853"},{"key":"ref194\/cit194","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)02807-6"},{"key":"ref195\/cit195","doi-asserted-by":"publisher","DOI":"10.3897\/ese.2022.e86910"},{"key":"ref196\/cit196","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-97-9959-6_9"},{"key":"ref197\/cit197","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2024.115347"},{"key":"ref198\/cit198","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2022.01.006"},{"key":"ref199\/cit199","doi-asserted-by":"publisher","DOI":"10.3390\/jpm14010053"},{"key":"ref200\/cit200","doi-asserted-by":"publisher","DOI":"10.1097\/PTS.0000000000001158"},{"key":"ref201\/cit201","doi-asserted-by":"publisher","DOI":"10.1200\/GO-24-00416"},{"key":"ref202\/cit202","doi-asserted-by":"publisher","DOI":"10.1016\/j.adro.2025.101824"},{"key":"ref203\/cit203","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2022.05.011"},{"key":"ref204\/cit204","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2023.08.035"},{"key":"ref205\/cit205","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.121.023294"},{"key":"ref206\/cit206","doi-asserted-by":"publisher","DOI":"10.1038\/s41698-022-00343-y"},{"key":"ref207\/cit207","doi-asserted-by":"publisher","DOI":"10.1007\/s40258-021-00714-9"},{"key":"ref208\/cit208","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2019.25.10.1082"},{"key":"ref209\/cit209","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2021-052926"},{"key":"ref210\/cit210","doi-asserted-by":"publisher","DOI":"10.1162\/99608f92.a9717b34"},{"key":"ref211\/cit211","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2025.1554948"},{"key":"ref212\/cit212","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-025-08118-4"},{"key":"ref213\/cit213","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-021-00844-4"},{"key":"ref214\/cit214","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgab434"},{"key":"ref215\/cit215","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.56344"},{"key":"ref216\/cit216","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2025.03.012"},{"key":"ref217\/cit217","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-77018-0"},{"key":"ref218\/cit218","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2024.02.008"},{"key":"ref219\/cit219","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2025.01.030"},{"key":"ref220\/cit220","doi-asserted-by":"publisher","DOI":"10.1038\/s41597-024-03349-2"},{"key":"ref221\/cit221","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32995-7"}],"container-title":["ACS Biomaterials Science &amp; Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsbiomaterials.5c00342","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsbiomaterials.5c00342","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T08:10:56Z","timestamp":1757319056000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsbiomaterials.5c00342"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,20]]},"references-count":221,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9,8]]}},"alternative-id":["10.1021\/acsbiomaterials.5c00342"],"URL":"https:\/\/doi.org\/10.1021\/acsbiomaterials.5c00342","relation":{},"ISSN":["2373-9878","2373-9878"],"issn-type":[{"value":"2373-9878","type":"print"},{"value":"2373-9878","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,20]]}}}