{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T12:26:29Z","timestamp":1794227189295,"version":"4.9.0"},"reference-count":54,"publisher":"American Chemical Society (ACS)","issue":"11","license":[{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["GM146771"],"award-info":[{"award-number":["GM146771"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,11,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>While the use of polymer micro- and nanoparticles for drug delivery has been demonstrated for diverse biomedical applications, not all techniques have allowed for the precise localization of the drug that is needed to support surrounding tissues. Herein, we report a biocompatible thermoplastic polyurethane silk fibroin composite drug delivery platform for localized drug release. The work leverages two distinct materials, combining the biocompatibility of silk fibroin protein particles as a drug carrier with the modularity of a thermoplastic polyurethane scaffold, whose mechanical properties are tuned by composition. Two different particle attachment strategies were investigated; a Michael addition reaction was found to result in a high number of particles attached and a more complete surface coverage than carbodiimide coupling that is often employed with silk-based materials. The attachment of silk fibroin microparticles allows localized delivery of molecules, and the incorporation of poly(tetrahydrofuran) (pTHF) into polyurethane was found to tailor phase separation of the hard and soft segments that, in turn, affects the crystallinity and stiffness of the scaffold. The hard segment crystallinity of unprocessed powders (range: 16.26\u201335.51%) and slow-cooled films (range: 9.04\u201337.29%) increased as the pTHF content increased, indicating an increase in phase separation. The Young\u2019s modulus of thermoplastic polyurethanes (TPUs) also increased with increasing pTHF, from 9.02 to 14.49 MPa. In vitro cytocompatibility testing with human dermal fibroblasts showed &amp;gt;85% viability and no significant changes in cell growth with respect to composition. This platform demonstrates a promising strategy by combining two distinct materials to provide localized drug delivery with potential application for longer-term biocompatible medical implants.<\/jats:p>","DOI":"10.1021\/acsbiomaterials.6c01093","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T11:01:48Z","timestamp":1791802908000},"page":"6079-6091","source":"Crossref","is-referenced-by-count":0,"title":["Surface Functionalization of Thermoplastic Polyurethane Scaffolds to Enhance Microparticle Attachment"],"prefix":"10.1021","volume":"12","author":[{"given":"Megan C.","family":"Welch","sequence":"first","affiliation":[{"name":"University of Connecticut , , , ,","place":["Storrs, Connecticut, United States, 06269"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney K.","family":"Rowe","sequence":"additional","affiliation":[{"name":"University of Connecticut School of Medicine , , , ,","place":["Farmington, Connecticut, United States, 06032"]},{"name":"Connecticut Children\u2019s Research Institute , , , ,","place":["Hartford, Connecticut, United States, 06108"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6741-0114","authenticated-orcid":true,"given":"Kelly A.","family":"Burke","sequence":"additional","affiliation":[{"name":"University of Connecticut , , , ,","place":["Storrs, Connecticut, United States, 06269"]},{"name":"University of Connecticut , , , ,","place":["Storrs, Connecticut, United States, 06269"]},{"name":"University of Connecticut , , , ,","place":["Storrs, Connecticut, United States, 06269"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,10,12]]},"reference":[{"issue":"1","key":"2026110907074206700_cit1","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1177\/1464420719882458","article-title":"Medical Devices Biomaterials \u2013 A Review","volume":"234","author":"Festas","year":"2020","journal-title":"Proc. Inst. Mech. Eng. Part J. Mater. Des. Appl."},{"issue":"2","key":"2026110907074206700_cit2","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1007\/s10439-015-1477-2","article-title":"Biomechanical Challenges to Polymeric Biodegradable Stents","volume":"44","author":"Soares","year":"2016","journal-title":"Ann. Biomed. Eng."},{"key":"2026110907074206700_cit3","doi-asserted-by":"publisher","first-page":"109","DOI":"10.2147\/RRU.S273663","article-title":"Catheter-Associated Urinary Tract Infections: Current Challenges and Future Prospects","volume":"14","author":"Werneburg","year":"2022","journal-title":"Res. Rep. Urol."},{"issue":"4","key":"2026110907074206700_cit4","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1021\/acsbiomaterials.5b00429","article-title":"Polymeric Biomaterials for Medical Implants and Devices","volume":"2","author":"Teo","year":"2016","journal-title":"ACS Biomater. Sci. Eng."},{"issue":"8","key":"2026110907074206700_cit5","doi-asserted-by":"publisher","first-page":"2025","DOI":"10.1039\/C8BM00518D","article-title":"Biocompatibility of Polymer-Based Biomaterials and Medical Devices \u2013 Regulations, in Vitro Screening and Risk-Management","volume":"6","author":"Bernard","year":"2018","journal-title":"Biomater. Sci."},{"issue":"12","key":"2026110907074206700_cit6","doi-asserted-by":"publisher","first-page":"17921","DOI":"10.1021\/acsami.4c16643","article-title":"Bioabsorbable Stent-Covering with Sustained Anticoagulant Activity Fabricated via Alternate Layer-by-Layer Self-Assembly of Heparin and Silk Fibroin","volume":"17","author":"Yu","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"4","key":"2026110907074206700_cit7","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1016\/j.addr.2012.03.009","article-title":"Naturally and Synthetic Smart Composite Biomaterials for Tissue Regeneration","volume":"65","author":"P\u00e9rez","year":"2013","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"27","key":"2026110907074206700_cit8","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202401218","article-title":"Extracellular Matrix-Surrogate Advanced Functional Composite Biomaterials for Tissue Repair and Regeneration","volume":"13","author":"Vahidi","year":"2024","journal-title":"Adv. Healthc. Mater."},{"issue":"16","key":"2026110907074206700_cit9","doi-asserted-by":"publisher","first-page":"4583","DOI":"10.1016\/j.biomaterials.2010.02.024","article-title":"Controlling Silk Fibroin Particle Features for Drug Delivery","volume":"31","author":"Lammel","year":"2010","journal-title":"Biomaterials"},{"issue":"6","key":"2026110907074206700_cit10","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1016\/j.biomaterials.2009.11.002","article-title":"Silk Nanospheres and Microspheres from Silk\/Pva Blend Films for Drug Delivery","volume":"31","author":"Wang","year":"2010","journal-title":"Biomaterials"},{"key":"2026110907074206700_cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2024.113286","article-title":"A Review of Silk Fibroin-Based Drug Delivery Systems and Their Applications","volume":"216","author":"Harishchandra Yadav","year":"2024","journal-title":"Eur. Polym. J."},{"key":"2026110907074206700_cit12","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.jconrel.2023.09.036","article-title":"An Overview of Polyurethane Biomaterials and Their Use in Drug Delivery","volume":"363","author":"Wienen","year":"2023","journal-title":"J. Controlled Release"},{"key":"2026110907074206700_cit13","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.actbio.2024.10.045","article-title":"Polymeric Artificial Heart Valves Derived from Modified Diol-Based Polycarbonate Polyurethanes","volume":"190","author":"Hu","year":"2024","journal-title":"Acta Biomater."},{"key":"2026110907074206700_cit14","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/j.msec.2016.10.019","article-title":"Rapid Hemostatic and Mild Polyurethane-Urea Foam Wound Dressing for Promoting Wound Healing","volume":"71","author":"Liu","year":"2017","journal-title":"Mater. Sci. Eng., C"},{"issue":"2","key":"2026110907074206700_cit15","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1021\/acsabm.2c00788","article-title":"Recent Advancements in Polyurethane-Based Tissue Engineering","volume":"6","author":"Singh","year":"2023","journal-title":"ACS Appl. Bio Mater."},{"issue":"115","key":"2026110907074206700_cit16","doi-asserted-by":"publisher","first-page":"114453","DOI":"10.1039\/C6RA14525F","article-title":"Polyurethane Types, Synthesis and Applications \u2013 a Review","volume":"6","author":"Akindoyo","year":"2016","journal-title":"RSC Adv."},{"issue":"11","key":"2026110907074206700_cit17","doi-asserted-by":"publisher","first-page":"6828","DOI":"10.1021\/acsbiomaterials.4c01352","article-title":"Polyurethanes and Their Biomedical Applications","volume":"10","author":"Azarmgin","year":"2024","journal-title":"ACS Biomater. Sci. Eng."},{"issue":"22","key":"2026110907074206700_cit18","doi-asserted-by":"publisher","first-page":"4137","DOI":"10.1039\/C7TB00419B","article-title":"Biocompatible, Degradable Thermoplastic Polyurethane Based on Polycaprolactone-Block-Polytetrahydrofuran-Block-Polycaprolactone Copolymers for Soft Tissue Engineering","volume":"5","author":"Mi","year":"2017","journal-title":"J. Mater. Chem. B"},{"issue":"7","key":"2026110907074206700_cit19","doi-asserted-by":"publisher","first-page":"2714","DOI":"10.1021\/acs.biomac.0c00456","article-title":"Zwitterion Surface-Functionalized Thermoplastic Polyurethane for Antifouling Catheter Applications","volume":"21","author":"Nikam","year":"2020","journal-title":"Biomacromolecules"},{"issue":"4","key":"2026110907074206700_cit20","doi-asserted-by":"publisher","DOI":"10.1002\/app.51666","article-title":"Thermoplastic Polyurethanes for Biomedical Application: A Synthetic, Mechanical, Antibacterial, and Cytotoxic Study","volume":"139","author":"Al Nakib","year":"2022","journal-title":"J. Appl. Polym. Sci."},{"issue":"4","key":"2026110907074206700_cit21","doi-asserted-by":"publisher","first-page":"1381","DOI":"10.1039\/D0BM01967D","article-title":"Thermoplastic Polyurethane with Controllable Degradation and Critical Anti-Fouling Properties","volume":"9","author":"Wang","year":"2021","journal-title":"Biomater. Sci."},{"issue":"1","key":"2026110907074206700_cit22","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1002\/jbm.b.33161","article-title":"Limitations of Predicting in Vivo Biostability of Multiphase Polyurethane Elastomers Using Temperature-Accelerated Degradation Testing: Temperature-Accelerated Degradation Testing","volume":"103","author":"Padsalgikar","year":"2015","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"issue":"1","key":"2026110907074206700_cit23","doi-asserted-by":"publisher","first-page":"3338","DOI":"10.1038\/s41467-024-47132-8","article-title":"Biocomposite Thermoplastic Polyurethanes Containing Evolved Bacterial Spores as Living Fillers to Facilitate Polymer Disintegration","volume":"15","author":"Kim","year":"2024","journal-title":"Nat. Commun."},{"key":"2026110907074206700_cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.polymertesting.2022.107489","article-title":"A Review of Microphase Separation of Polyurethane: Characterization and Applications","volume":"107","author":"Cheng","year":"2022","journal-title":"Polym. Test."},{"issue":"1","key":"2026110907074206700_cit25","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1007\/s00289-021-03615-y","article-title":"Molecular Dynamics Simulation, Synthesis and Characterization of Polyurethane Block Polymers Containing PTHF\/PCL Mixture as a Soft Segment","volume":"79","author":"Mirhosseini","year":"2022","journal-title":"Polym. Bull."},{"issue":"7","key":"2026110907074206700_cit26","doi-asserted-by":"publisher","first-page":"2096","DOI":"10.1016\/j.eurpolymj.2009.03.013","article-title":"Synthesis and Microstructure\u2013Mechanical Property Relationships of Segmented Polyurethanes Based on a PCL\u2013PTHF\u2013PCL Block Copolymer as Soft Segment","volume":"45","author":"Rueda-Larraz","year":"2009","journal-title":"Eur. Polym. J."},{"issue":"10","key":"2026110907074206700_cit27","doi-asserted-by":"publisher","first-page":"1612","DOI":"10.1038\/nprot.2011.379","article-title":"Materials Fabrication from Bombyx Mori Silk Fibroin","volume":"6","author":"Rockwood","year":"2011","journal-title":"Nat. Protoc."},{"issue":"19","key":"2026110907074206700_cit28","doi-asserted-by":"publisher","first-page":"2829","DOI":"10.1016\/j.biomaterials.2008.03.039","article-title":"Modification of Silk Fibroin Using Diazonium Coupling Chemistry and the Effects on hMSC Proliferation and Differentiation","volume":"29","author":"Murphy","year":"2008","journal-title":"Biomaterials"},{"issue":"6","key":"2026110907074206700_cit29","doi-asserted-by":"publisher","first-page":"2845","DOI":"10.1021\/acsbiomaterials.1c00481","article-title":"Sustainable Antibacterial Surgical Suture Using a Facile Scalable Silk-Fibroin-Based Berberine Loading System","volume":"7","author":"Wu","year":"2021","journal-title":"ACS Biomater. Sci. Eng."},{"key":"2026110907074206700_cit30","doi-asserted-by":"publisher","first-page":"4613","DOI":"10.1016\/j.ijbiomac.2020.08.041","article-title":"Silk Fibroin and Silk-Based Biomaterial Derivatives for Ideal Wound Dressings","volume":"164","author":"Patil","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"issue":"8","key":"2026110907074206700_cit31","doi-asserted-by":"publisher","first-page":"3049","DOI":"10.1016\/j.actbio.2012.04.035","article-title":"Novel Silk Fibroin\/Elastin Wound Dressings","volume":"8","author":"Vasconcelos","year":"2012","journal-title":"Acta Biomater."},{"issue":"38","key":"2026110907074206700_cit32","doi-asserted-by":"publisher","first-page":"5410","DOI":"10.1016\/j.vaccine.2021.07.064","article-title":"Enhancing Influenza Vaccine Immunogenicity and Efficacy through Infection Mimicry Using Silk Microneedles","volume":"39","author":"Stinson","year":"2021","journal-title":"Vaccine"},{"issue":"1","key":"2026110907074206700_cit33","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1002\/adhm.201300139","article-title":"Implantable Silk Composite Microneedles for Programmable Vaccine Release Kinetics and Enhanced Immunogenicity in Transcutaneous Immunization","volume":"3","author":"DeMuth","year":"2014","journal-title":"Adv. Healthc. Mater."},{"issue":"5","key":"2026110907074206700_cit34","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1016\/j.jvoice.2018.01.017","article-title":"Injectable Silk Protein Microparticle-Based Fillers: A Novel Material for Potential Use in Glottic Insufficiency","volume":"33","author":"Brown","year":"2019","journal-title":"J. Voice"},{"issue":"24","key":"2026110907074206700_cit35","doi-asserted-by":"publisher","first-page":"21813","DOI":"10.1021\/am502278b","article-title":"Regenerated Silk Fibroin Films with Controllable Nanostructure Size and Secondary Structure for Drug Delivery","volume":"6","author":"Zhou","year":"2014","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"6","key":"2026110907074206700_cit36","doi-asserted-by":"publisher","DOI":"10.1002\/mame.202000130","article-title":"Electroactive Silk Fibroin Films for Electrochemically Enhanced Delivery of Drugs","volume":"305","author":"Mousavi","year":"2020","journal-title":"Macromol. Mater. Eng."},{"issue":"1","key":"2026110907074206700_cit37","doi-asserted-by":"publisher","first-page":"11913","DOI":"10.1038\/s41598-017-12351-1","article-title":"Drug Release from Core-Shell PVA\/Silk Fibroin Nanoparticles Fabricated by One-Step Electrospraying","volume":"7","author":"Cao","year":"2017","journal-title":"Sci. Rep."},{"issue":"70","key":"2026110907074206700_cit38","doi-asserted-by":"publisher","first-page":"41074","DOI":"10.1039\/C9RA09344C","article-title":"Design and Performance of a Poly(Vinyl Alcohol)\/Silk Fibroin Enzymatically Crosslinked Semi-Interpenetrating Hydrogel for a Potential Hydrophobic Drug Delivery","volume":"9","author":"Niu","year":"2019","journal-title":"RSC Adv."},{"issue":"21","key":"2026110907074206700_cit39","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201801005","article-title":"Silk Fibroin Microparticles with Hollow Mesoporous Silica Nanocarriers Encapsulation for Abdominal Wall Repair","volume":"7","author":"Zhao","year":"2018","journal-title":"Adv. Healthc. Mater."},{"issue":"6","key":"2026110907074206700_cit40","doi-asserted-by":"publisher","first-page":"065031","DOI":"10.1088\/1748-605X\/ad8850","article-title":"Silk Fibroin Microspheres with Photothermal Nanocarrier Encapsulation for Anticancer Drug Delivery","volume":"19","author":"Lu","year":"2024","journal-title":"Biomed. Mater."},{"issue":"20","key":"2026110907074206700_cit41","doi-asserted-by":"publisher","first-page":"18967","DOI":"10.1021\/acsanm.3c03451","article-title":"Silk Nanoparticle Synthesis: Tuning Size, Dispersity, and Surface Chemistry for Drug Delivery","volume":"6","author":"Shaidani","year":"2023","journal-title":"ACS Appl. Nano Mater."},{"issue":"5","key":"2026110907074206700_cit42","doi-asserted-by":"publisher","first-page":"2796","DOI":"10.1021\/acsbiomaterials.0c00202","article-title":"Manual Versus Microfluidic-Assisted Nanoparticle Manufacture: Impact of Silk Fibroin Stock on Nanoparticle Characteristics","volume":"6","author":"Solomun","year":"2020","journal-title":"ACS Biomater. Sci. Eng."},{"key":"2026110907074206700_cit43","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1007\/s40883-025-00427-8","article-title":"Silk Fibroin Particle-Laden Sponges as a Multiphase Controlled Release Platform","author":"Pacheco","year":"2025","journal-title":"Regen. Eng. Transl. Med."},{"issue":"42","key":"2026110907074206700_cit44","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202303718","article-title":"Non-Pore Dependent and MMP-9 Responsive Gelatin\/Silk Fibroin Composite Microparticles as Universal Delivery Platform for Inhaled Treatment of Lung Cancer","volume":"35","author":"Gou","year":"2023","journal-title":"Adv. Mater."},{"key":"2026110907074206700_cit45","doi-asserted-by":"publisher","first-page":"2018","DOI":"10.1016\/j.ijbiomac.2020.07.326","article-title":"Surface Modified Silk Fibroin Nanoparticles for Improved Delivery of Doxorubicin: Development, Characterization, in-Vitro Studies","volume":"164","author":"Pandey","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"issue":"4","key":"2026110907074206700_cit46","doi-asserted-by":"publisher","first-page":"3319","DOI":"10.1007\/s10853-018-3022-9","article-title":"Fabricated Porous Silk Fibroin Particles for pH-Responsive Drug Delivery and Targeting of Tumor Cells","volume":"54","author":"Sun","year":"2019","journal-title":"J. Mater. Sci."},{"issue":"1","key":"2026110907074206700_cit47","doi-asserted-by":"publisher","DOI":"10.1002\/marc.201800390","article-title":"Experimental Methods for Characterizing the Secondary Structure and Thermal Properties of Silk Proteins","volume":"40","author":"McGill","year":"2019","journal-title":"Macromol. Rapid Commun."},{"key":"2026110907074206700_cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.polymertesting.2024.108329","article-title":"Visualization and Quantification of Microphase Separation in Thermoplastic Polyurethanes under Different Hard Segment Contents and Its Effect on the Mechanical Properties","volume":"131","author":"Huang","year":"2024","journal-title":"Polym. Test."},{"key":"2026110907074206700_cit49","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/S0141-3910(01)00018-0","article-title":"Effect of Photoirradiation on Potassium Persulfate-Surface Oxidation of Low-Density Polyethylene Film","volume":"72","author":"Kubota","year":"2001","journal-title":"Polym. Degrad. Stabil."},{"issue":"7","key":"2026110907074206700_cit50","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1038\/nprot.2008.75","article-title":"Neutral Red Uptake Assay for the Estimation of Cell Viability\/Cytotoxicity","volume":"3","author":"Repetto","year":"2008","journal-title":"Nat. Protoc."},{"issue":"14","key":"2026110907074206700_cit51","doi-asserted-by":"publisher","first-page":"3213","DOI":"10.1016\/j.polymer.2010.04.069","article-title":"Elasticity and Inelasticity of Thermoplastic Polyurethane Elastomers: Sensitivity to Chemical and Physical Structure","volume":"51","author":"Buckley","year":"2010","journal-title":"Polymer"},{"issue":"1","key":"2026110907074206700_cit52","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.biomaterials.2006.08.002","article-title":"Preparation and Characterization of Cross-Linked Collagen\u2013Phospholipid Polymer Hybrid Gels","volume":"28","author":"Nam","year":"2007","journal-title":"Biomaterials"},{"issue":"46","key":"2026110907074206700_cit53","doi-asserted-by":"publisher","first-page":"10827","DOI":"10.1016\/j.tet.2005.08.031","article-title":"Amide Bond Formation and Peptide Coupling","volume":"61","author":"Montalbetti","year":"2005","journal-title":"Tetrahedron"},{"issue":"5","key":"2026110907074206700_cit54","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1016\/j.progpolymsci.2006.03.001","article-title":"Michael Addition Reactions in Macromolecular Design for Emerging Technologies","volume":"31","author":"Mather","year":"2006","journal-title":"Prog. Polym. Sci."}],"container-title":["ACS Biomaterials Science &amp; Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsbiomaterials.6c01093","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/abseba\/article-pdf\/12\/11\/6079\/68818373\/ab-2026-010936.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/abseba\/article-pdf\/12\/11\/6079\/68818373\/ab-2026-010936.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T12:18:10Z","timestamp":1794226690000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/abseba\/article\/12\/11\/6079\/5448911\/Surface-Functionalization-of-Thermoplastic"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,12]]},"references-count":54,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2026,10,12]]},"published-print":{"date-parts":[[2026,11,9]]}},"URL":"https:\/\/doi.org\/10.1021\/acsbiomaterials.6c01093","relation":{"has-part":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsbiomaterials.6c01093.s001","asserted-by":"subject"}]},"ISSN":["2373-9878"],"issn-type":[{"value":"2373-9878","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,12]]}}}