{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:48:19Z","timestamp":1790671699885,"version":"4.1.0"},"reference-count":51,"publisher":"American Chemical Society (ACS)","issue":"6","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100005492","name":"Stanford University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["R01AR063717-06"],"award-info":[{"award-number":["R01AR063717-06"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["R01AR073145-01"],"award-info":[{"award-number":["R01AR073145-01"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Biomater. Sci. Eng."],"published-print":{"date-parts":[[2019,6,10]]},"DOI":"10.1021\/acsbiomaterials.9b00560","type":"journal-article","created":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T21:45:36Z","timestamp":1556747136000},"page":"3032-3038","source":"Crossref","is-referenced-by-count":12,"title":["Treating Titanium Particle-Induced Inflammation with Genetically Modified NF-\u03baB Sensing IL-4 Secreting or Preconditioned Mesenchymal Stem Cells in Vitro"],"prefix":"10.1021","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1821-4560","authenticated-orcid":true,"given":"Yusuke","family":"Kohno","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Stanford University, Stanford, California 94063, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tzuhua","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Stanford University, Stanford, California 94063, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jukka","family":"Pajarinen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Stanford University, Stanford, California 94063, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eemeli","family":"J\u00e4msen","sequence":"additional","affiliation":[{"name":"Department of Medicine, Clinicum, University of Helsinki and Helsinki University Hospital, Helsinki 00029, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Romero-Lopez","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Stanford University, Stanford, California 94063, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Stanford University, Stanford, California 94063, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Wen","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Stanford University, Stanford, California 94063, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Ueno","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Stanford University, Stanford, California 94063, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karthik","family":"Nathan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Stanford University, Stanford, California 94063, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyu","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Stanford University, Stanford, California 94063, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart B.","family":"Goodman","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Stanford University, Stanford, California 94063, United States"},{"name":"Department of Bioengineering, Stanford University, Stanford, California 94305, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2019,5,1]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2010.03.046"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2013.3271"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200800001-00003"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2013.06.027"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/nri978"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199905000-00002"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.34599"},{"key":"ref8\/cit8","first-page":"713","volume":"32","author":"Mandelin J.","year":"2005","journal-title":"J. Rheumatol"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-014-3786-4"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2016.02.020"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/nri910"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcyt.2017.06.008"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.3727\/096368915X689622"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.10.017"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.10.019"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2013.09.034"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2014.164"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-016-0276-5"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2007.11.014"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2011.189"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/nm.1905"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-017-0730-z"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.36504"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0142736"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.32495"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100170603"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2089"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b10184"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1300532110"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1054\/arth.2002.32697"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200800001-00004"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2013.0962"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1080\/17453674.2017.1402463"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.12.025"},{"key":"ref35\/cit35","first-page":"65","volume":"46","author":"Gong L.","year":"2016","journal-title":"Ann. Clin Lab Sci."},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-017-2598-8"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(92)90248-J"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1007\/BF03347799"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.47.293"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3109\/00365513.2010.488698"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20140643"},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"8672","DOI":"10.1128\/jvi.71.11.8672-8677.1997","volume":"71","author":"Fischer J. E.","year":"1997","journal-title":"J. Virol"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.04.024"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.166.4.2775"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1159\/000332235"},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"4344","DOI":"10.4049\/jimmunol.151.8.4344","volume":"151","author":"Allen J. B.","year":"1993","journal-title":"J. Immunol"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.02.043"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0010088"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellbi.2009.03.006"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tec.2017.0166"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcyt.2018.06.009"}],"container-title":["ACS Biomaterials Science &amp; Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsbiomaterials.9b00560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T11:11:36Z","timestamp":1682507496000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsbiomaterials.9b00560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,1]]},"references-count":51,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6,10]]}},"alternative-id":["10.1021\/acsbiomaterials.9b00560"],"URL":"https:\/\/doi.org\/10.1021\/acsbiomaterials.9b00560","relation":{},"ISSN":["2373-9878","2373-9878"],"issn-type":[{"value":"2373-9878","type":"print"},{"value":"2373-9878","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,1]]}}}