{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T21:36:02Z","timestamp":1790631362334,"version":"4.1.0"},"reference-count":52,"publisher":"American Chemical Society (ACS)","issue":"12","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000165","name":"Division of Chemistry","doi-asserted-by":"publisher","award":["CHE-1845486"],"award-info":[{"award-number":["CHE-1845486"]}],"id":[{"id":"10.13039\/100000165","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R35GM133469"],"award-info":[{"award-number":["R35GM133469"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Chem. Biol."],"published-print":{"date-parts":[[2022,12,16]]},"DOI":"10.1021\/acschembio.2c00653","type":"journal-article","created":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T12:05:05Z","timestamp":1669896305000},"page":"3478-3488","source":"Crossref","is-referenced-by-count":6,"title":["Design, Synthesis, and Characterization of a Novel 2\u2032\u20135\u2032-Linked Amikacin-Binding Aptamer: An Experimental and MD Simulation Study"],"prefix":"10.1021","volume":"17","author":[{"given":"Johnsi","family":"Mathivanan","sequence":"first","affiliation":[{"name":"Department of Chemistry and the RNA Institute, University at Albany, State University of New York, Albany, New York12222, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixue","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Chemistry and the RNA Institute, University at Albany, State University of New York, Albany, New York12222, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8246-2935","authenticated-orcid":true,"given":"Alan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Chemistry and the RNA Institute, University at Albany, State University of New York, Albany, New York12222, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6198-390X","authenticated-orcid":true,"given":"Jia","family":"Sheng","sequence":"additional","affiliation":[{"name":"Department of Chemistry and the RNA Institute, University at Albany, State University of New York, Albany, New York12222, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkx1030"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq1028"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2012.07.011"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.2013.774366"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(81)90425-6"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(84)90553-1"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(84)90468-9"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3742"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1089\/jir.2014.0007"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/268537a0"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01471-07"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkr586"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.1.19-25.2001"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1317799111"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2016.199"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a027029"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.4137\/PMC.S2381"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/jm061200+"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.1468"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1715501114"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/S0969-2126(99)80105-1"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/1804"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.1402"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1039\/D0OB02104K"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.cplett.2021.138819"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2019.05.001"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jctc.0c00340"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/ja963909j"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.7b00287"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/ja076529e"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.0c10991"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(01)76250-9"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/ja005538j"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1309392110"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.0c00735"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa737"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1080\/00268976.2014.952696"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-5-367"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.softx.2015.06.001"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btt055"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/ct700301q"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20291"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1007\/s008940100045"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/0010-4655(95)00042-E"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/ct300613v"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/jp8001614"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmgm.2003.12.009"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/jp807701h"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmgm.2019.107441"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1021\/ct400689h"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/jp9110794"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1021\/ct100494z"}],"container-title":["ACS Chemical Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acschembio.2c00653","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acschembio.2c00653","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T13:18:45Z","timestamp":1682428725000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acschembio.2c00653"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,1]]},"references-count":52,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12,16]]}},"alternative-id":["10.1021\/acschembio.2c00653"],"URL":"https:\/\/doi.org\/10.1021\/acschembio.2c00653","relation":{},"ISSN":["1554-8929","1554-8937"],"issn-type":[{"value":"1554-8929","type":"print"},{"value":"1554-8937","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,1]]}}}