{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T04:25:46Z","timestamp":1776313546173,"version":"3.50.1"},"reference-count":58,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100003006","name":"Eidgen?ssische Technische Hochschule Z?rich","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003006","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007352","name":"Staatssekretariat f?r Bildung, Forschung und Innovation","doi-asserted-by":"publisher","award":["MB22.00050"],"award-info":[{"award-number":["MB22.00050"]}],"id":[{"id":"10.13039\/501100007352","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008375","name":"Universit?t Basel","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008375","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Chem. Biol."],"published-print":{"date-parts":[[2025,4,18]]},"DOI":"10.1021\/acschembio.4c00692","type":"journal-article","created":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T15:46:12Z","timestamp":1743522372000},"page":"791-801","source":"Crossref","is-referenced-by-count":2,"title":["Amber Codon Mutational Scanning and Bioorthogonal PEGylation for Epitope Mapping of Antibody Binding Sites on Human Arginase-1"],"prefix":"10.1021","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3739-3632","authenticated-orcid":true,"given":"Jaime","family":"Fern\u00e1ndez de Santaella","sequence":"first","affiliation":[{"name":"Institute of Physical Chemistry, Department of Chemistry","place":["Basel, Switzerland"]},{"name":"University of Basel","place":["Basel, Switzerland"]},{"name":"Department of Biosystems Science and Engineering","place":["Basel, Switzerland"]},{"name":"ETH Zurich","place":["Basel, Switzerland"]},{"name":"National Center for Competence in Research (NCCR)","place":["Basel, Switzerland"]},{"name":"Molecular Systems Engineering","place":["Basel, Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2745-0020","authenticated-orcid":true,"given":"Nikolaj G.","family":"Koch","sequence":"additional","affiliation":[{"name":"Institute of Physical Chemistry, Department of Chemistry","place":["Basel, Switzerland"]},{"name":"University of Basel","place":["Basel, Switzerland"]},{"name":"Department of Biosystems Science and Engineering","place":["Basel, Switzerland"]},{"name":"ETH Zurich","place":["Basel, Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenz","family":"Widmer","sequence":"additional","affiliation":[{"name":"Institute of Physical Chemistry, Department of Chemistry","place":["Basel, Switzerland"]},{"name":"University of Basel","place":["Basel, Switzerland"]},{"name":"Department of Biosystems Science and Engineering","place":["Basel, Switzerland"]},{"name":"ETH Zurich","place":["Basel, Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3842-1567","authenticated-orcid":true,"given":"Michael A.","family":"Nash","sequence":"additional","affiliation":[{"name":"Institute of Physical Chemistry, Department of Chemistry","place":["Basel, Switzerland"]},{"name":"University of Basel","place":["Basel, Switzerland"]},{"name":"Department of Biosystems Science and Engineering","place":["Basel, Switzerland"]},{"name":"ETH Zurich","place":["Basel, Switzerland"]},{"name":"National Center for Competence in Research (NCCR)","place":["Basel, Switzerland"]},{"name":"Molecular Systems Engineering","place":["Basel, Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2025,4,1]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2009.07.001"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.37349\/eds.2023.00025"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3390\/antib7020019"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2020.08.005"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1080\/19420862.2022.2028337"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1080\/19420862.2023.2285285"},{"key":"ref7\/cit7","first-page":"13","volume-title":"Methods in Molecular Biology","volume":"1785","author":"King M. T.","year":"2018"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/jmr.2454"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-021-02444-z"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-020-03091-9"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.3c00816"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.3c00159"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/ac2007366"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-017-1601-7"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.3389\/frans.2023.1118749"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1272"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M113.033308"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1089\/mab.2021.0028"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.RA120.002314"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2021.02.003"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.676635"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2014.09.020"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/bit.26706"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c05869"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2022.997653"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2016.12.016"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.160252097"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.08.012"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.4c00031"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00184C"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201608438"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2019.02.020"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.052308.105824"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.4c00221"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acssynbio.1c00626"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3390\/ijms161025831"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1007\/s00726-015-2032-z"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2004.11.004"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2023.102405"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28052150"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-1945"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2019.12.005"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21155291"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-019-0231-3"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2024.2318053"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2017.1404215"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/nrd818"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2024.149534"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.2c05429"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-45630-3"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4029"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201700327"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1128\/JB.182.13.3726-3733.2000"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","unstructured":"Koch, N. G.; Goettig, P.; Rappsilber, J.; Budisa, N. \u201ccold\u201d Orthogonal Translation by Psychrophilic Pyrrolysyl-TRNA Synthetase Boosts Genetic Code Expansion\n                      bioRxiv\n                      2023 10.1101\/2023.05.23.541947.","DOI":"10.1101\/2023.05.23.541947"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2021.807438"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1021\/cb5006273"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1038\/srep09699"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1007\/s41061-024-00467-8"}],"container-title":["ACS Chemical Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acschembio.4c00692","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acschembio.4c00692","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T04:11:32Z","timestamp":1744949492000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acschembio.4c00692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,1]]},"references-count":58,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4,18]]}},"alternative-id":["10.1021\/acschembio.4c00692"],"URL":"https:\/\/doi.org\/10.1021\/acschembio.4c00692","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.08.20.608740","asserted-by":"object"}]},"ISSN":["1554-8929","1554-8937"],"issn-type":[{"value":"1554-8929","type":"print"},{"value":"1554-8937","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,1]]}}}