{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T03:50:45Z","timestamp":1788493845980,"version":"build-2803163510"},"reference-count":44,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100019180","name":"HORIZON EUROPE European Research Council","doi-asserted-by":"publisher","award":["802940"],"award-info":[{"award-number":["802940"]}],"id":[{"id":"10.13039\/100019180","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100024870","name":"Exacte en Natuurwetenschappen","doi-asserted-by":"publisher","award":["NWO-024.002.009"],"award-info":[{"award-number":["NWO-024.002.009"]}],"id":[{"id":"10.13039\/501100024870","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Chem. Biol."],"published-print":{"date-parts":[[2026,5,15]]},"DOI":"10.1021\/acschembio.5c00968","type":"journal-article","created":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T01:44:08Z","timestamp":1775699048000},"page":"960-971","source":"Crossref","is-referenced-by-count":2,"title":["An Environment-Sensitive Turn-On Fluorescent Probe Enables Detection of PAD4 Activation in Response to Distinct NETosis Stimuli"],"prefix":"10.1021","volume":"21","author":[{"given":"Enebie","family":"Ramos C\u00e1ceres","sequence":"first","affiliation":[{"name":"Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, Nijmegen 6525AJ, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moniek M.","family":"Bioch","sequence":"additional","affiliation":[{"name":"Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, Nijmegen 6525AJ, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike L.W.J.","family":"Smeenk","sequence":"additional","affiliation":[{"name":"Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, Nijmegen 6525AJ, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rocaya C.","family":"Gro\u00df","sequence":"additional","affiliation":[{"name":"Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, Leiden 2333 CC, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9498-2620","authenticated-orcid":true,"given":"Kimberly M.","family":"Bonger","sequence":"additional","affiliation":[{"name":"Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, Leiden 2333 CC, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2019.01.024"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1111\/jth.15313"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-020-0409-1"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics14112414"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2011.03.028"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.20431"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M208795200"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2003.012211"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01200"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-33385-z"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.1735"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1126\/science.1092385"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1134\/S0006297920100065"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.24437"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201006052"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2014.06.044"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.3390\/cells11182889"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1909546117"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06263-5"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cellbio-020520-111016"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-018-0261-x"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200806072"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20100239"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2018.08.014"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12834"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/ja308871v"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.5b00438"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1007\/82_2018_132"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201208464"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/cb1003515"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.7b00957"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/bip.21605"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b01059"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2021.666605"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201302884"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.6b00517"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/s42004-024-01338-5"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.7b00274"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.761946"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02428"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-018-0048-3"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1006\/abio.2000.4805"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.3791\/62837"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2818.2006.01706.x"}],"container-title":["ACS Chemical Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acschembio.5c00968","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acschembio.5c00968","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T08:13:16Z","timestamp":1778832796000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acschembio.5c00968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,8]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5,15]]}},"alternative-id":["10.1021\/acschembio.5c00968"],"URL":"https:\/\/doi.org\/10.1021\/acschembio.5c00968","relation":{},"ISSN":["1554-8929","1554-8937"],"issn-type":[{"value":"1554-8929","type":"print"},{"value":"1554-8937","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,8]]}}}