{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T08:00:12Z","timestamp":1774080012716,"version":"3.50.1"},"reference-count":30,"publisher":"American Chemical Society (ACS)","issue":"2","funder":[{"DOI":"10.13039\/501100009023","name":"Precursory Research for Embryonic Science and Technology","doi-asserted-by":"publisher","award":["JPMJPR1687"],"award-info":[{"award-number":["JPMJPR1687"]}],"id":[{"id":"10.13039\/501100009023","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Chem. Biol."],"published-print":{"date-parts":[[2018,2,16]]},"DOI":"10.1021\/acschembio.7b01058","type":"journal-article","created":{"date-parts":[[2018,1,12]],"date-time":"2018-01-12T15:28:41Z","timestamp":1515770921000},"page":"449-454","source":"Crossref","is-referenced-by-count":20,"title":["Generation of Optogenetically Modified Adenovirus Vector for Spatiotemporally Controllable Gene Therapy"],"prefix":"10.1021","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1132-2457","authenticated-orcid":true,"given":"Kazuo","family":"Takayama","sequence":"first","affiliation":[{"name":"Laboratory\rof Biochemistry and Molecular Biology, Graduate School of Pharmaceutical\rSciences, Osaka University, Osaka 565-0871, Japan"},{"name":"PRESTO, Japan Science and Technology Agency, Saitama 332-0012, Japan"},{"name":"Laboratory\rof Hepatocyte Regulation, National Institute of Biomedical Innovation, Health and Nutrition, Osaka 567-0085, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Mizuguchi","sequence":"additional","affiliation":[{"name":"Laboratory\rof Biochemistry and Molecular Biology, Graduate School of Pharmaceutical\rSciences, Osaka University, Osaka 565-0871, Japan"},{"name":"Laboratory\rof Hepatocyte Regulation, National Institute of Biomedical Innovation, Health and Nutrition, Osaka 567-0085, Japan"},{"name":"Global\rCenter for Medical Engineering and Informatics, Osaka University, Osaka 565-0871, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2018,1,12]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1111\/cas.13228"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.5169"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-bioeng-071813-104938"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.04.059"},{"key":"ref5\/cit5","first-page":"3625","volume":"7","author":"Lohr F.","year":"2001","journal-title":"Clin. Cancer Res."},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/nn1525"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/nature09886"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1126\/science.1225829"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2842"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/ja3065667"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.2205"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3245"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2014.12.011"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.1753"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3301115"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4165(01)00194-5"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3301453"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/jgm.348"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2011.234"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2012.04.038"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2017.04.006"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(68)90121-9"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-0829"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/cgt.2016.53"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.3.1767"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3630"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3199"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.7567\/JJAP.56.057001"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/srep21247"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/srep16533"}],"container-title":["ACS Chemical Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acschembio.7b01058","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T04:04:25Z","timestamp":1682568265000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acschembio.7b01058"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,12]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2,16]]}},"alternative-id":["10.1021\/acschembio.7b01058"],"URL":"https:\/\/doi.org\/10.1021\/acschembio.7b01058","relation":{},"ISSN":["1554-8929","1554-8937"],"issn-type":[{"value":"1554-8929","type":"print"},{"value":"1554-8937","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,12]]}}}