{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T17:39:40Z","timestamp":1781977180808,"version":"3.54.5"},"reference-count":49,"publisher":"American Chemical Society (ACS)","issue":"6","license":[{"start":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T00:00:00Z","timestamp":1559001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T00:00:00Z","timestamp":1559001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T00:00:00Z","timestamp":1559001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100007515","name":"Universidad de Valladolid","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007515","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003852","name":"Regione Campania","doi-asserted-by":"publisher","award":["I-Cure"],"award-info":[{"award-number":["I-Cure"]}],"id":[{"id":"10.13039\/501100003852","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Consejer\u00eda de Sanidad, Junta de Castilla y Le\u00f3n","award":["BIO\/VA39\/14"],"award-info":[{"award-number":["BIO\/VA39\/14"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Chem. Biol."],"published-print":{"date-parts":[[2019,6,21]]},"DOI":"10.1021\/acschembio.9b00291","type":"journal-article","created":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T22:48:46Z","timestamp":1559083726000},"page":"1319-1327","source":"Crossref","is-referenced-by-count":44,"title":["Ageritin, a Ribotoxin from Poplar Mushroom (<i>Agrocybe aegerita<\/i>) with Defensive and Antiproliferative Activities"],"prefix":"10.1021","volume":"14","author":[{"given":"Luc\u00eda","family":"Citores","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, E\u221247011 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Ragucci","sequence":"additional","affiliation":[{"name":"Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania \u201cLuigi Vanvitelli\u201d, I-81100 Caserta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4816-5878","authenticated-orcid":true,"given":"Jos\u00e9 M.","family":"Ferreras","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, E\u221247011 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9595-9665","authenticated-orcid":true,"given":"Antimo","family":"Di Maro","sequence":"additional","affiliation":[{"name":"Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania \u201cLuigi Vanvitelli\u201d, I-81100 Caserta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5021-1733","authenticated-orcid":true,"given":"Rosario","family":"Iglesias","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, E\u221247011 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2019,5,28]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","DOI":"10.1201\/b15139","volume-title":"Mushroom Pest and Disease Control: A Colour Handbook","author":"Fletcher J. T.","year":"2007"},{"key":"ref2\/cit2","first-page":"1","volume-title":"Progress in the Chemistry of Organic Natural Products","volume":"106","author":"Chen H.-P.","year":"2017"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-016-7671-9"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/978-94-007-6214-5_24","volume-title":"Antitumor Potential and Other Emerging Medicinal Properties of Natural Compounds","author":"Wong J. H.","year":"2013"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/B978-0-12-802794-3.00008-4","volume-title":"Mushroom Biotechnology","author":"Barseghyan G. S.","year":"2016"},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/B978-012369442-3\/50022-2","volume-title":"Handbook of Biologically Active Peptides","author":"Chu K. T.","year":"2006"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2006.00063.x"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3390\/toxins9020071"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq151"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2012.03.016"},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/B978-012588945-2\/50005-4","volume-title":"Ribonucleases. Structures and Functions","author":"Wool I. G.","year":"1997"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(82)91868-X"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1099\/13500872-141-6-1343"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1515\/hsz-2016-0119"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1093\/protein\/gzs032"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1186\/s40064-015-0943-5"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1111\/febs.13169"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1093\/protein\/gzw045"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2015.01.062"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2014.02.022"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1128\/am.13.3.314-321.1965","volume":"13","author":"Olson B. H.","year":"1965","journal-title":"Appl. Microbiol."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.1016\/S0021-9258(18)32977-6","volume":"258","author":"Endo Y.","year":"1983","journal-title":"J. Biol. Chem."},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ibmb.2012.10.008"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.8b00410"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2017.02.023"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2018.09.010"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1093\/jb\/mvy113"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1007\/s13337-018-0434-8"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gnh182"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(94)90055-8"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/wrna.1196"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21121627"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1007\/s11103-014-0204-y"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv348"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2005.01.015"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1007\/s00425-014-2191-2"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-006-0362-1"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1327.2001.02086.x"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1110\/ps.9601"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2015.01.007"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(95)80421-2"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0082485"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1111\/mpp.12278"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2008.12.005"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(83)90286-6"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2091-10-9"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2011.06.017"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.21769\/BioProtoc.2180"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2017.11.014"}],"container-title":["ACS Chemical Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acschembio.9b00291","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T08:25:29Z","timestamp":1682497529000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acschembio.9b00291"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,28]]},"references-count":49,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6,21]]}},"alternative-id":["10.1021\/acschembio.9b00291"],"URL":"https:\/\/doi.org\/10.1021\/acschembio.9b00291","relation":{},"ISSN":["1554-8929","1554-8937"],"issn-type":[{"value":"1554-8929","type":"print"},{"value":"1554-8937","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,28]]}}}