{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T09:26:22Z","timestamp":1787045182181,"version":"build-2736575974"},"reference-count":28,"publisher":"American Chemical Society (ACS)","issue":"7","license":[{"start":{"date-parts":[[2020,5,10]],"date-time":"2020-05-10T00:00:00Z","timestamp":1589068800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-001"},{"start":{"date-parts":[[2020,5,10]],"date-time":"2020-05-10T00:00:00Z","timestamp":1589068800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-009"},{"start":{"date-parts":[[2020,5,10]],"date-time":"2020-05-10T00:00:00Z","timestamp":1589068800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Novel beta-coronavirus SARS-CoV-2 is the pathogenic agent responsible for coronavirus disease-2019 (COVID-19), a globally pandemic infectious disease. Due to its high virulence and the absence of immunity among the general population, SARS-CoV-2 has quickly spread to all countries. This pandemic highlights the urgent unmet need to expand and focus our research tools on what are considered \u201cneglected infectious diseases\u201d and to prepare for future inevitable pandemics. This global emergency has generated unprecedented momentum and scientific efforts around the globe unifying scientists from academia, government and the pharmaceutical industry to accelerate the discovery of vaccines and treatments. Herein, we shed light on the virus structure and life cycle and the potential therapeutic targets in SARS-CoV-2 and briefly refer to both active and passive immunization modalities, drug repurposing focused on speed to market, and novel agents against specific viral targets as therapeutic interventions for COVID-19.<\/jats:p>","DOI":"10.1021\/acsinfecdis.0c00224","type":"journal-article","created":{"date-parts":[[2020,5,10]],"date-time":"2020-05-10T12:17:49Z","timestamp":1589113069000},"page":"1548-1552","source":"Crossref","is-referenced-by-count":40,"title":["COVID-19: Living through Another Pandemic"],"prefix":"10.1021","volume":"6","author":[{"given":"Essam Eldin A.","family":"Osman","sequence":"first","affiliation":[{"name":"University of Michigan , , , ,","place":["Ann Arbor, Michigan, United States, 48109"]},{"name":"Cairo University , , ,","place":["Cairo, Egypt, 11562"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter L.","family":"Toogood","sequence":"additional","affiliation":[{"name":"University of Michigan , , , ,","place":["Ann Arbor, Michigan, United States, 48109"]},{"name":"University of Michigan , , , ,","place":["Ann Arbor, Michigan, United States, 48109"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3291-7131","authenticated-orcid":true,"given":"Nouri","family":"Neamati","sequence":"additional","affiliation":[{"name":"University of Michigan , , , ,","place":["Ann Arbor, Michigan, United States, 48109"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2020,5,10]]},"reference":[{"issue":"7798","key":"2026081722183657100_cit1","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1038\/s41586-020-2008-3","article-title":"A new coronavirus\nassociated with human respiratory disease in China","volume":"579","author":"Wu","year":"2020","journal-title":"Nature"},{"issue":"1","key":"2026081722183657100_cit2","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1080\/22221751.2020.1719902","article-title":"Genomic characterization\nof the 2019 novel human-pathogenic coronavirus isolated from a patient\nwith atypical pneumonia after visiting Wuhan","volume":"9","author":"Chan","year":"2020","journal-title":"Emerging Microbes Infect."},{"issue":"3","key":"2026081722183657100_cit3","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1128\/MMBR.00004-08","article-title":"Cross-species virus transmission\nand the emergence of new epidemic diseases","volume":"72","author":"Parrish","year":"2008","journal-title":"Microbiol. 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Math Methods Med."},{"issue":"4","key":"2026081722183657100_cit7","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1038\/s41564-020-0695-z","article-title":"The species severe acute respiratory\nsyndrome-related coronavirus: classifying 2019-nCoV and naming it\nSARS-CoV-2","volume":"5","author":"Coronaviridae\nStudy Group of the International Committee on Taxonomy of Viruses","year":"2020","journal-title":"Nat. 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