{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:04:32Z","timestamp":1792091072120,"version":"4.4.0"},"reference-count":57,"publisher":"American Chemical Society (ACS)","issue":"8","license":[{"start":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T00:00:00Z","timestamp":1623369600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T00:00:00Z","timestamp":1623369600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T00:00:00Z","timestamp":1623369600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00c3\u00b6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["JPIAMR RIBOTARGET"],"award-info":[{"award-number":["JPIAMR RIBOTARGET"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI123352"],"award-info":[{"award-number":["AI123352"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010767","name":"Innovative Medicines Initiative","doi-asserted-by":"publisher","award":["n_115583"],"award-info":[{"award-number":["n_115583"]}],"id":[{"id":"10.13039\/501100010767","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2021,8,13]]},"DOI":"10.1021\/acsinfecdis.1c00158","type":"journal-article","created":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T14:16:49Z","timestamp":1623421009000},"page":"2413-2424","source":"Crossref","is-referenced-by-count":16,"title":["Synthesis and Antibacterial Activity of Propylamycin Derivatives Functionalized at the 5\u2032\u2032- and Other Positions with a View to Overcoming Resistance Due to Aminoglycoside Modifying Enzymes"],"prefix":"10.1021","volume":"7","author":[{"given":"Dimitrijs","family":"Lubriks","sequence":"first","affiliation":[{"name":"Latvian Institute of Organic Synthesis, Riga, Latvia LV-1006"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rimants","family":"Zogota","sequence":"additional","affiliation":[{"name":"Latvian Institute of Organic Synthesis, Riga, Latvia LV-1006"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9855-8923","authenticated-orcid":true,"given":"Vikram A.","family":"Sarpe","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Biomedical Sciences, University of Georgia, 250 West Green Street, Athens, Georgia 30602, United States"},{"name":"Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, Georgia 30602, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiko","family":"Matsushita","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2861-9353","authenticated-orcid":true,"given":"Girish C.","family":"Sati","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klara","family":"Haldimann","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology, University of Zurich, Gloriastrasse 28, 8006 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Gysin","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology, University of Zurich, Gloriastrasse 28, 8006 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik C.","family":"B\u00f6ttger","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology, University of Zurich, Gloriastrasse 28, 8006 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Vasella","sequence":"additional","affiliation":[{"name":"Organic Chemistry Laboratory, ETH Z\u00fcrich, Vladimir-Prelog-Weg 1-5\/10, 8093 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3078-0576","authenticated-orcid":true,"given":"Edgars","family":"Suna","sequence":"additional","affiliation":[{"name":"Latvian Institute of Organic Synthesis, Riga, Latvia LV-1006"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven N.","family":"Hobbie","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology, University of Zurich, Gloriastrasse 28, 8006 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2400-0083","authenticated-orcid":true,"given":"David","family":"Crich","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Biomedical Sciences, University of Georgia, 250 West Green Street, Athens, Georgia 30602, United States"},{"name":"Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, Georgia 30602, United States"},{"name":"Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States"},{"name":"Department of Chemistry, University of Georgia, 140 Cedar Street, Athens, Georgia 30602, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,6,11]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b01693"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.9b00441"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2020.127218"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2020.02.008"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2017.117"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1039\/C5MD00384A"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/cr0301088"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.2174\/156802610793176684"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1039\/C5MD00344J"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23020284"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-1400-1_7"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq408"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.8b00001"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.8b00052"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2016.02.011"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.11.4.619"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.2741\/Wright"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b11601"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.202000726"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.34.1434"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b12420"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b04050"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.0c00861"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.6b00288"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b04279"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.5b02204"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/nature11687"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1126\/science.aba2419"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/jlac.197419740606"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/0008-6215(83)88062-8"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/jo052662i"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)88016-9"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2020.107984"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1039\/P19900001677"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/jo990686h"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.0c00743"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.6b00214"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01827-14"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)00216-6"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/327389a0"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki862"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1126\/science.274.5291.1367"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-062917-011942"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2017.00308"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2013.01.006"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/ng0793-289"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/937861"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0811258106"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0707265105"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00965-08"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm658"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1039\/C8MD00001H"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.120.265595"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1039\/C4MD00081A"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1204073109"},{"key":"ref56\/cit56","volume-title":"Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically","author":"Clinical Laboratory Standards Institute","year":"2015","edition":"10"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky546"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.1c00158","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T09:51:45Z","timestamp":1688377905000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.1c00158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,11]]},"references-count":57,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8,13]]}},"alternative-id":["10.1021\/acsinfecdis.1c00158"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.1c00158","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,11]]}}}