{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:36:04Z","timestamp":1790620564983,"version":"4.1.0"},"reference-count":76,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T00:00:00Z","timestamp":1649635200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T00:00:00Z","timestamp":1649635200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T00:00:00Z","timestamp":1649635200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R00CA163671"],"award-info":[{"award-number":["R00CA163671"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA188382"],"award-info":[{"award-number":["R01CA188382"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2022,5,13]]},"DOI":"10.1021\/acsinfecdis.1c00530","type":"journal-article","created":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T20:12:18Z","timestamp":1649707938000},"page":"969-981","source":"Crossref","is-referenced-by-count":7,"title":["Microbial Imbalance Induces Inflammation by Promoting <i>Salmonella<\/i> Penetration through the Mucosal Barrier"],"prefix":"10.1021","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6273-0119","authenticated-orcid":true,"given":"Abhinav","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Chemical Engineering, University of Massachusetts, Amherst, Massachusetts 01003, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishnu","family":"Raman","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering, University of Massachusetts, Amherst, Massachusetts 01003, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2048-2142","authenticated-orcid":true,"given":"Jungwoo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering, University of Massachusetts, Amherst, Massachusetts 01003, United States"},{"name":"Molecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, Massachusetts 01003, United States"},{"name":"Institute for Applied Life Sciences, University of Massachusetts, Amherst, Massachusetts 01003, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil S.","family":"Forbes","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering, University of Massachusetts, Amherst, Massachusetts 01003, United States"},{"name":"Molecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, Massachusetts 01003, United States"},{"name":"Institute for Applied Life Sciences, University of Massachusetts, Amherst, Massachusetts 01003, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,4,11]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20539"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/ctg.2016.54"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.01835"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3402\/mehd.v26.26191"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/nri2653"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.03.011"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0050244"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-008-0079-7"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1080\/21553769.2015.1051243"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.02.004"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.05.081"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.04.001"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2017.11.006"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-86-21030"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2014.07.028"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.4161\/gmic.19325"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00022-13"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv571"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.7.3380-3389.2005"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjv223"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012238"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000688"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1001097"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2007.08.002"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2538"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1006451107"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0803124105"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1038\/nri1499"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.5217\/ir.2015.13.1.11"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2018-317571"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.43.2.143"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2608"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.12.8785"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2011.00088"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1128\/iai.56.9.2209-2217.1988"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2008.01118.x"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.7.4138-4150.2004"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.04.106"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1002\/bit.27383"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2021.08.007"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000037"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2011.11.013"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/nri1499"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-008-9571-x"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/35074106"},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"3749","DOI":"10.4049\/jimmunol.162.7.3749","volume":"162","author":"Hoshino K.","year":"1999","journal-title":"J. Immun."},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.061168"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1111\/1751-2980.12540"},{"key":"ref49\/cit49","first-page":"997","volume":"144","author":"Mazzucchelli L.","year":"1994","journal-title":"Am. J. Pathol."},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/nri3661"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1007\/s12602-012-9092-0"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2010.117"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2017.08.003"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.01889"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14203"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1038\/nmicrobiol.2016.215"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.3390\/nu10111723"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/9478630"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.3390\/nu12061581"},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1136\/gut.53.1.108","volume":"53","author":"Mimura T.","year":"2004","journal-title":"Gut"},{"key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s13099-017-0168-y","volume":"9","author":"Ekmekciu I.","year":"2017","journal-title":"Gut Pathog."},{"key":"ref62\/cit62","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jhin.2013.02.019","volume":"84","author":"Selinger C. P.","year":"2013","journal-title":"J. Hosp. Infect."},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/135.12.2753"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.9b00851"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.2001.280.5.G922"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002810"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00603-19"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0159676"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2014.07.028"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1137292"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1135392"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20377"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v22.i24.5505"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0257824"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1021\/js960110x"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1186\/s40425-018-0490-z"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.1c00530","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.1c00530","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T03:54:13Z","timestamp":1682481253000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.1c00530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,11]]},"references-count":76,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5,13]]}},"alternative-id":["10.1021\/acsinfecdis.1c00530"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.1c00530","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,11]]}}}