{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T04:50:47Z","timestamp":1784695847153,"version":"3.55.0"},"reference-count":32,"publisher":"American Chemical Society (ACS)","issue":"10","license":[{"start":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T00:00:00Z","timestamp":1694736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T00:00:00Z","timestamp":1694736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T00:00:00Z","timestamp":1694736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01 AI109023"],"award-info":[{"award-number":["R01 AI109023"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01 AI143714"],"award-info":[{"award-number":["R01 AI143714"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R33 AI125781"],"award-info":[{"award-number":["R33 AI125781"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["W81XWH2210520"],"award-info":[{"award-number":["W81XWH2210520"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2023,10,13]]},"DOI":"10.1021\/acsinfecdis.3c00310","type":"journal-article","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T11:58:50Z","timestamp":1694779130000},"page":"2036-2047","source":"Crossref","is-referenced-by-count":14,"title":["Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in <i>Plasmodium falciparum<\/i>"],"prefix":"10.1021","volume":"9","author":[{"given":"John M.","family":"Bennett","sequence":"first","affiliation":[{"name":"Department of Chemistry, Stanford University, Stanford, California 94305, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3614-436X","authenticated-orcid":true,"given":"Kurt E.","family":"Ward","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Columbia University Medical Center, New York, New York 10032, United States"},{"name":"Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Medical Center, New York, New York 10032, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan K.","family":"Muir","sequence":"additional","affiliation":[{"name":"Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Kabeche","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5982-1979","authenticated-orcid":true,"given":"Euna","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States"},{"name":"Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Yeo","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Columbia University Medical Center, New York, New York 10032, United States"},{"name":"Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Medical Center, New York, New York 10032, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Lam","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California 94304, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1187-5844","authenticated-orcid":true,"given":"Hao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York 10065, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jehad","family":"Almaliti","sequence":"additional","affiliation":[{"name":"Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Berger","sequence":"additional","affiliation":[{"name":"Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco F.","family":"Faucher","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Stanford University, Stanford, California 94305, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4797-7073","authenticated-orcid":true,"given":"Gang","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York 10065, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William H.","family":"Gerwick","sequence":"additional","affiliation":[{"name":"Scripps Institution of Oceanography, University of California San Diego, La Jolla, California 92037, United States"},{"name":"Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States"},{"name":"Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94304, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Fidock","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Columbia University Medical Center, New York, New York 10032, United States"},{"name":"Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Medical Center, New York, New York 10032, United States"},{"name":"Division of Infectious Diseases, Columbia University Medical Center, New York, New York 10032, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3753-4412","authenticated-orcid":true,"given":"Matthew","family":"Bogyo","sequence":"additional","affiliation":[{"name":"Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States"},{"name":"Scripps Institution of Oceanography, University of California San Diego, La Jolla, California 92037, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,9,15]]},"reference":[{"key":"ref1\/cit1","unstructured":"World Malaria Report 2022; World Health\nOrganization: Geneva, 2022."},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc0900231"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-1005-2"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2101746"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1126\/science.1260867"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1314981"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2012.09.019"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06221-1"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/nature16936"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.7b00671"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b06656"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2107213118"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007722"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2017.06.052"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.6b00838"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/ja507692y"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202015845"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.2c00611"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2023.03.002"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2014.01.003"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.62.6.714"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3390\/biom9120822"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.8b00819"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1039\/C9MD00396G"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030949"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2021.04.006"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-38774-1"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10245845"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1039\/C9CS00720B"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1177\/1087057116671509"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27072261"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(04)00111-4"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.3c00310","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.3c00310","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T08:18:45Z","timestamp":1697185125000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.3c00310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,15]]},"references-count":32,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10,13]]}},"alternative-id":["10.1021\/acsinfecdis.3c00310"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.3c00310","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,15]]}}}