{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T00:51:33Z","timestamp":1775868693660,"version":"3.50.1"},"reference-count":70,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T00:00:00Z","timestamp":1712361600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T00:00:00Z","timestamp":1712361600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T00:00:00Z","timestamp":1712361600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100012453","name":"China Agricultural Research System","doi-asserted-by":"publisher","award":["CARS-35"],"award-info":[{"award-number":["CARS-35"]}],"id":[{"id":"10.13039\/501100012453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFD1800900"],"award-info":[{"award-number":["2022YFD1800900"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019035","name":"Science and Technology Program of Hubei Province","doi-asserted-by":"publisher","award":["2022ABA002"],"award-info":[{"award-number":["2022ABA002"]}],"id":[{"id":"10.13039\/501100019035","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019222","name":"Walmart Food Safety Collaboration Center","doi-asserted-by":"publisher","award":["61626817"],"award-info":[{"award-number":["61626817"]}],"id":[{"id":"10.13039\/501100019222","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2024,5,10]]},"DOI":"10.1021\/acsinfecdis.3c00611","type":"journal-article","created":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T13:20:30Z","timestamp":1712409630000},"page":"1576-1589","source":"Crossref","is-referenced-by-count":8,"title":["Discovery of Salifungin as a Repurposed Antibiotic against Methicillin-Resistant <i>Staphylococcus aureus<\/i> with Limited Resistance Development"],"prefix":"10.1021","volume":"10","author":[{"given":"Chenchen","family":"Wang","sequence":"first","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430000, Hubei, China"},{"name":"Hubei Hongshan Laboratory, Wuhan 430000, Hubei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yueyue","family":"Ji","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430000, Hubei, China"},{"name":"Hubei Hongshan Laboratory, Wuhan 430000, Hubei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingyu","family":"Huo","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430000, Hubei, China"},{"name":"Hubei Hongshan Laboratory, Wuhan 430000, Hubei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaodan","family":"Li","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430000, Hubei, China"},{"name":"Hubei Hongshan Laboratory, Wuhan 430000, Hubei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjia","family":"Lu","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430000, Hubei, China"},{"name":"Hubei Hongshan Laboratory, Wuhan 430000, Hubei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaoran","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430000, Hubei, China"},{"name":"Hubei Hongshan Laboratory, Wuhan 430000, Hubei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenqi","family":"Dong","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430000, Hubei, China"},{"name":"Hubei Hongshan Laboratory, Wuhan 430000, Hubei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0191-1378","authenticated-orcid":true,"given":"Xiangru","family":"Wang","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430000, Hubei, China"},{"name":"Hubei Hongshan Laboratory, Wuhan 430000, Hubei, China"},{"name":"Frontiers Science Center for Animal Breeding and Sustainable Production, Wuhan 430000, Hubei, China"},{"name":"Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan 430000, Hubei, China"},{"name":"The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430000, Hubei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huanchun","family":"Chen","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430000, Hubei, China"},{"name":"Hubei Hongshan Laboratory, Wuhan 430000, Hubei, China"},{"name":"Frontiers Science Center for Animal Breeding and Sustainable Production, Wuhan 430000, Hubei, China"},{"name":"Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan 430000, Hubei, China"},{"name":"The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430000, Hubei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4622-4483","authenticated-orcid":true,"given":"Chen","family":"Tan","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430000, Hubei, China"},{"name":"Hubei Hongshan Laboratory, Wuhan 430000, Hubei, China"},{"name":"Frontiers Science Center for Animal Breeding and Sustainable Production, Wuhan 430000, Hubei, China"},{"name":"Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan 430000, Hubei, China"},{"name":"The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430000, Hubei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2024,4,6]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(21)02724-0"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro727"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2014.06.018"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-food-030212-182653"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2010.06.006"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1086\/595011"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2019.111743"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202100749"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.113691"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/nmicrobiol.2016.51"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2474"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2015.10.018"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2015.199"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/448645a"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.2174\/1381612823666170209154745"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00594-16"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2022.05.124"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0711697105"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.71.10.3896"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.ra117.001231"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1039\/C4MD00012A"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/s1473-3099(17)30753-3"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00377-16"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0124595"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0089189"},{"issue":"4","key":"ref26\/cit26","first-page":"313","volume":"36","author":"Knychalska-Karwan Z.","year":"1983","journal-title":"Czas. Stomatol."},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/S0232-4393(11)80219-2"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1912345116"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.02068-20"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1128\/aac.02574-18"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/jm0000057"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.7554\/elife.65836"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2023.07.038"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1128\/aac.01846-16"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkaa103"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.01720"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1904700116"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkac319"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2009.12.011"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1088\/1748-605x\/aa7105"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1038\/nature15709"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2019.12.008"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.790"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2012.00195"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.01140-20"},{"key":"ref46\/cit46","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing","author":"Clinical and Laboratory Standards Institute","year":"2007"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1111\/j.0014-3820.2001.tb00606.x"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2017.03.020"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2014.03.004"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aay9597"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201902227"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1611173113"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2208348120"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.01801-21"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/ct700301q"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/s0006-3495(97)78845-3"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1605030113"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b06963"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27051485"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2020.1770493"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1002\/mbo3.720"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.720685"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1039\/C9FO01233H"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-016-7396-9"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.7150\/thno.39157"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkr198"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22115829"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1080\/21655979.2021.1943113"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.2174\/1381612821666150506154434"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00714-10"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.3c00611","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.3c00611","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T08:11:39Z","timestamp":1715328699000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.3c00611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,6]]},"references-count":70,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5,10]]}},"alternative-id":["10.1021\/acsinfecdis.3c00611"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.3c00611","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,6]]}}}