{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T22:06:08Z","timestamp":1793743568088,"version":"4.6.1"},"reference-count":55,"publisher":"American Chemical Society (ACS)","issue":"3","license":[{"start":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:00:00Z","timestamp":1707177600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012453","name":"China Agricultural Research System","doi-asserted-by":"publisher","award":["CARS-35"],"award-info":[{"award-number":["CARS-35"]}],"id":[{"id":"10.13039\/501100012453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFD1800800"],"award-info":[{"award-number":["2021YFD1800800"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2022M721277"],"award-info":[{"award-number":["2022M721277"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003819","name":"Natural Science Foundation of Hubei Province","doi-asserted-by":"publisher","award":["2021CFA016"],"award-info":[{"award-number":["2021CFA016"]}],"id":[{"id":"10.13039\/501100003819","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2662023PY005"],"award-info":[{"award-number":["2662023PY005"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32102749"],"award-info":[{"award-number":["32102749"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2024,3,8]]},"DOI":"10.1021\/acsinfecdis.3c00668","type":"journal-article","created":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T03:27:45Z","timestamp":1707190065000},"page":"988-999","source":"Crossref","is-referenced-by-count":36,"title":["Interleukin-22 Contributes to Blood\u2013Brain Barrier Disruption via STAT3\/VEGFA Activation in\n                    <i>Escherichia coli<\/i>\n                    Meningitis"],"prefix":"10.1021","volume":"10","author":[{"given":"Ruicheng","family":"Yang","sequence":"first","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China"},{"name":"Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqi","family":"Chen","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China"},{"name":"Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Qu","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China"},{"name":"Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hulin","family":"Liu","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China"},{"name":"Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Wang","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China"},{"name":"Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4622-4483","authenticated-orcid":true,"given":"Chen","family":"Tan","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China"},{"name":"Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China"},{"name":"Frontiers Science Center for Animal Breeding and Sustainable Production, Wuhan 430070, China"},{"name":"International Research Center for Animal Disease, Ministry of Science and Technology of the People\u2019s Republic of China, Wuhan 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanchun","family":"Chen","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China"},{"name":"Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China"},{"name":"Frontiers Science Center for Animal Breeding and Sustainable Production, Wuhan 430070, China"},{"name":"International Research Center for Animal Disease, Ministry of Science and Technology of the People\u2019s Republic of China, Wuhan 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0191-1378","authenticated-orcid":true,"given":"Xiangru","family":"Wang","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China"},{"name":"Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China"},{"name":"Frontiers Science Center for Animal Breeding and Sustainable Production, Wuhan 430070, China"},{"name":"International Research Center for Animal Disease, Ministry of Science and Technology of the People\u2019s Republic of China, Wuhan 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,2,6]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2021.103274"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.01233-23"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-019-1497-1"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-023-02856-0"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2009.07.030"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20190062"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1186\/s12987-022-00346-8"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.1036123"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24032852"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.3105cm1"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/166.2.350"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1086\/515079"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23073693"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M005304200"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/nrd4176"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2025"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.851818"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-020-01928-9"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2020.11348"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.958022"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.5009\/gnl.2014.8.3.237"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.11696"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-024-01488-y"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2012.07.063"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1186\/s13041-021-00826-2"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1086\/379042"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2022.814867"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2008.9"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.38925"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.05.032"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/art.24220"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.02148"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/iub.2295"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2021.119195"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1801308"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.955576"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.13817"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.01160"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.2011.02536.x"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/nm1651"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2019.116929"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-021-01293-5"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1111\/cns.13699"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.21037\/atm-20-7024"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-018-1147-z"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2016.88"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-018-1260-z"},{"issue":"9","key":"ref48\/cit48","first-page":"2019","volume":"9","author":"Huang J.","year":"2019","journal-title":"Am. J. Cancer Res."},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/glia.22857"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-017-0769-y"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000131634.57368.45"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19051362"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awab387"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-022-02514-x"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1101\/gr.136184.111"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.3c00668","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.3c00668","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T04:13:19Z","timestamp":1709871199000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.3c00668"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,6]]},"references-count":55,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3,8]]}},"alternative-id":["10.1021\/acsinfecdis.3c00668"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.3c00668","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,6]]}}}