{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T19:46:04Z","timestamp":1793907964911,"version":"4.8.0"},"reference-count":74,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T00:00:00Z","timestamp":1712275200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100005156","name":"Alexander von Humboldt-Stiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005156","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2024,5,10]]},"DOI":"10.1021\/acsinfecdis.4c00045","type":"journal-article","created":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T08:44:23Z","timestamp":1712306663000},"page":"1696-1710","source":"Crossref","is-referenced-by-count":24,"title":["Targeting Intracellular Bacteria with Dual Drug-loaded Lactoferrin Nanoparticles"],"prefix":"10.1021","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1183-2307","authenticated-orcid":true,"given":"Moses","family":"Andima","sequence":"first","affiliation":[{"name":"Department of Drug Delivery (DDEL), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research, Campus E8.1, Saarbr\u00fccken 66123, Germany"},{"name":"Department of Chemistry, Faculty of Science and Education, Busitema University, P.O Box 236, Tororo 21435, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Boese","sequence":"additional","affiliation":[{"name":"Department of Drug Delivery (DDEL), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research, Campus E8.1, Saarbr\u00fccken 66123, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of Drug Delivery (DDEL), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research, Campus E8.1, Saarbr\u00fccken 66123, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Koch","sequence":"additional","affiliation":[{"name":"INM-Leibniz Institute for New Materials, Campus D2 2, Saarbr\u00fccken 66123, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitta","family":"Loretz","sequence":"additional","affiliation":[{"name":"Department of Drug Delivery (DDEL), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research, Campus E8.1, Saarbr\u00fccken 66123, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus-Micheal","family":"Lehr","sequence":"additional","affiliation":[{"name":"Department of Drug Delivery (DDEL), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research, Campus E8.1, Saarbr\u00fccken 66123, Germany"},{"name":"Department of Pharmacy, Saarland University, Saarbr\u00fccken 66123, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,4,5]]},"reference":[{"key":"ref1\/cit1","unstructured":"World\nHealth Organisation The top 10 causes\nof death. 2020."},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1179\/2047773215Y.0000000030"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1007\/s13346-021-01009-1"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1039\/D1MH02042K"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2021.113948"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.112609"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2020.00286"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3109\/10717544.2014.880756"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/476534"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1007\/s12088-018-0740-2"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006244"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-36-3-177"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2017.00245"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1139\/o11-058"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.120355"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1007\/BF02818693"},{"issue":"4","key":"ref17\/cit17","first-page":"96","volume":"1","author":"Godowski K. C.","year":"1989","journal-title":"J. Clin. Dent."},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3390\/ph13010013"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2020.111003"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.9543"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.00801"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.22038\/IJBMS.2022.62541.13851"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.00621"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics12070604"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.2c00356"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2018.00021"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.7150\/jca.7093"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2017.00505"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202102117"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1517\/17425247.2012.717927"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.3c00189"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003300"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1517\/14728222.7.3.311"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3201\/eid2404.170095"},{"issue":"2","key":"ref35\/cit35","first-page":"110","volume":"39","author":"Khorshidi A.","year":"2010","journal-title":"Iran J. Public Health"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S357077"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(96)00545-6"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-020-04706-3"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2010.0759"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3390\/molecules19056583"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1111\/1751-7915.14017"},{"issue":"4","key":"ref42\/cit42","first-page":"694","volume":"19","author":"Bruniera F. R.","year":"2015","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/19.1.101"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2008.11.005"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.00905"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.01977"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/476393a"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2536"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1007\/s10534-022-00455-9"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1080\/08927014.2013.773317"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201402969"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2020.11.107"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1139\/bcb-2020-0079"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2022.01.017"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00179-11"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1007\/s00203-020-02071-y"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2011.11.001"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1128\/JB.181.15.4443-4451.1999"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-022-01204-x"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio717"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-76332-7"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-76332-7"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1039\/C8SM00925B"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-022-03443-3"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2015.03.015"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2021.04.012"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1038\/nature16057"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-017-0187-5"},{"key":"ref69\/cit69","volume-title":"Reference Module in Biomedical Sciences","author":"Gutierrez C.","year":"2014"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms11010090"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3270"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.2174\/157489209789206869"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00834-19"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02554-20"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.4c00045","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.4c00045","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T08:11:34Z","timestamp":1715328694000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.4c00045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,5]]},"references-count":74,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5,10]]}},"alternative-id":["10.1021\/acsinfecdis.4c00045"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.4c00045","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,5]]}}}