{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T10:38:43Z","timestamp":1788950323229,"version":"build-2803163510"},"reference-count":31,"publisher":"American Chemical Society (ACS)","issue":"6","license":[{"start":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T00:00:00Z","timestamp":1715904000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["CB21\/13\/00100"],"award-info":[{"award-number":["CB21\/13\/00100"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007757","name":"Agencia Canaria de Investigaci\u00f3n, Innovaci\u00f3n y Sociedad de la Informaci\u00f3n","doi-asserted-by":"publisher","award":["TESIS 2020010063"],"award-info":[{"award-number":["TESIS 2020010063"]}],"id":[{"id":"10.13039\/501100007757","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019170","name":"Cabildo de Tenerife","doi-asserted-by":"publisher","award":["CABILDO.23"],"award-info":[{"award-number":["CABILDO.23"]}],"id":[{"id":"10.13039\/501100019170","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019170","name":"Cabildo de Tenerife","doi-asserted-by":"publisher","award":["CC20230222"],"award-info":[{"award-number":["CC20230222"]}],"id":[{"id":"10.13039\/501100019170","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100023961","name":"Centro de Investigaci\u00f3n Biotecnol\u00f3gica en Red de Enfermedades Infecciosas","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023961","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016145","name":"Ministerio de Sanidad","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100016145","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2024,6,14]]},"DOI":"10.1021\/acsinfecdis.4c00062","type":"journal-article","created":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T11:18:28Z","timestamp":1715944708000},"page":"2063-2073","source":"Crossref","is-referenced-by-count":6,"title":["Flucofuron as a Promising Therapeutic Agent against Brain-Eating Amoeba"],"prefix":"10.1021","volume":"10","author":[{"given":"Javier","family":"Chao-Pellicer","sequence":"first","affiliation":[{"name":"Instituto Universitario de Enfermedades Tropicales y Salud P\u00fablica de Canarias, Universidad de La Laguna, Avda. Astrof\u00edsico Fco. S\u00e1nchez, S\/N, 38203 San Crist\u00f3bal de La Laguna, Spain"},{"name":"Departamento de Obstetricia y Ginecolog\u00eda, Pediatr\u00eda, Medicina Preventiva y Salud P\u00fablica, Toxicolog\u00eda, Medicina Legal y Forense y Parasitolog\u00eda, Universidad de La Laguna, 38203 San Crist\u00f3bal de La Laguna, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28220 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I\u00f1igo","family":"Arberas-Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Instituto Universitario de Enfermedades Tropicales y Salud P\u00fablica de Canarias, Universidad de La Laguna, Avda. Astrof\u00edsico Fco. S\u00e1nchez, S\/N, 38203 San Crist\u00f3bal de La Laguna, Spain"},{"name":"Departamento de Obstetricia y Ginecolog\u00eda, Pediatr\u00eda, Medicina Preventiva y Salud P\u00fablica, Toxicolog\u00eda, Medicina Legal y Forense y Parasitolog\u00eda, Universidad de La Laguna, 38203 San Crist\u00f3bal de La Laguna, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Sifaoui","sequence":"additional","affiliation":[{"name":"Instituto Universitario de Enfermedades Tropicales y Salud P\u00fablica de Canarias, Universidad de La Laguna, Avda. Astrof\u00edsico Fco. S\u00e1nchez, S\/N, 38203 San Crist\u00f3bal de La Laguna, Spain"},{"name":"Departamento de Obstetricia y Ginecolog\u00eda, Pediatr\u00eda, Medicina Preventiva y Salud P\u00fablica, Toxicolog\u00eda, Medicina Legal y Forense y Parasitolog\u00eda, Universidad de La Laguna, 38203 San Crist\u00f3bal de La Laguna, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28220 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 E.","family":"Pi\u00f1ero","sequence":"additional","affiliation":[{"name":"Instituto Universitario de Enfermedades Tropicales y Salud P\u00fablica de Canarias, Universidad de La Laguna, Avda. Astrof\u00edsico Fco. S\u00e1nchez, S\/N, 38203 San Crist\u00f3bal de La Laguna, Spain"},{"name":"Departamento de Obstetricia y Ginecolog\u00eda, Pediatr\u00eda, Medicina Preventiva y Salud P\u00fablica, Toxicolog\u00eda, Medicina Legal y Forense y Parasitolog\u00eda, Universidad de La Laguna, 38203 San Crist\u00f3bal de La Laguna, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28220 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7683-2888","authenticated-orcid":true,"given":"Jacob","family":"Lorenzo-Morales","sequence":"additional","affiliation":[{"name":"Instituto Universitario de Enfermedades Tropicales y Salud P\u00fablica de Canarias, Universidad de La Laguna, Avda. Astrof\u00edsico Fco. S\u00e1nchez, S\/N, 38203 San Crist\u00f3bal de La Laguna, Spain"},{"name":"Departamento de Obstetricia y Ginecolog\u00eda, Pediatr\u00eda, Medicina Preventiva y Salud P\u00fablica, Toxicolog\u00eda, Medicina Legal y Forense y Parasitolog\u00eda, Universidad de La Laguna, 38203 San Crist\u00f3bal de La Laguna, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28220 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,5,17]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2011.07.023"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.6b00232"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01293-15"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1093\/femsec\/fiaa238"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1128\/mr.52.1.114-133.1988"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.3390\/biom11091320"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003017"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2019.06.011"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.6b00197"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268809991014"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1645\/0022-3395(2000)086[0050:ALMSOT]2.0.CO;2"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/piu103"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejop.2015.07.003"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-2712(18)30524-9"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00875-06"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2018.02.010"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2023.0189"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3201\/eid1010.040273"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2004.11.003"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.00515-22"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1128\/aem.63.6.2421-2431.1997"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/a802528b"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1759(96)00098-1"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-014-8166-0"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2021.102092"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1809422115"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkv367"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2016.01.075"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.4.1907-1916.2005"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.000500"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-018-0563-0"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.4c00062","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.4c00062","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T09:09:22Z","timestamp":1718356162000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.4c00062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,17]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6,14]]}},"alternative-id":["10.1021\/acsinfecdis.4c00062"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.4c00062","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,17]]}}}