{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T12:12:15Z","timestamp":1777119135477,"version":"3.51.4"},"reference-count":48,"publisher":"American Chemical Society (ACS)","issue":"12","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001412","name":"Council of Scientific and Industrial Research, India","doi-asserted-by":"publisher","award":["09\/1278(18646)\/2024-EMR-I"],"award-info":[{"award-number":["09\/1278(18646)\/2024-EMR-I"]}],"id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","award":["EEQ\/2019\/000294"],"award-info":[{"award-number":["EEQ\/2019\/000294"]}],"id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006593","name":"Board of Research in Nuclear Sciences","doi-asserted-by":"publisher","award":["54\/14\/15\/2020-BRNS\/35054"],"award-info":[{"award-number":["54\/14\/15\/2020-BRNS\/35054"]}],"id":[{"id":"10.13039\/501100006593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2024,12,13]]},"DOI":"10.1021\/acsinfecdis.4c00670","type":"journal-article","created":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T18:57:37Z","timestamp":1730487457000},"page":"4314-4326","source":"Crossref","is-referenced-by-count":4,"title":["Design, Synthesis, and Biological Studies of C-5-Substituted Diazenyl Derivatives of Uracil as Potent and Selective Antileishmanial Agents Targeting Uridine Biosynthesis Pathway Enzymes"],"prefix":"10.1021","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3521-8788","authenticated-orcid":true,"given":"Tushar","family":"Das","sequence":"first","affiliation":[{"name":"Applied Chemistry Laboratory, Department of Chemistry, National Institute of Technology Patna, Ashok Rajpath 800005, Bihar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prakash","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, National Institute of Pharmaceutical Education and Research Hajipur, Vaishali 844102, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachin","family":"Kumar","sequence":"additional","affiliation":[{"name":"Applied Chemistry Laboratory, Department of Chemistry, National Institute of Technology Patna, Ashok Rajpath 800005, Bihar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susital","family":"Mal","sequence":"additional","affiliation":[{"name":"Applied Chemistry Laboratory, Department of Chemistry, National Institute of Technology Patna, Ashok Rajpath 800005, Bihar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saurabh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, National Institute of Pharmaceutical Education and Research Hajipur, Vaishali 844102, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinod Kumar","family":"Rajana","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, National Institute of Pharmaceutical Education and Research Hajipur, Vaishali 844102, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shriya","family":"Singh","sequence":"additional","affiliation":[{"name":"Molecular Microbiology and Immunology Division, CSIR-Central Drug Research Institute, Sitapur Road, Sector-10, Jankipuram Extension, Lucknow 226031, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9014-1904","authenticated-orcid":true,"given":"Arunava","family":"Dasgupta","sequence":"additional","affiliation":[{"name":"Molecular Microbiology and Immunology Division, CSIR-Central Drug Research Institute, Sitapur Road, Sector-10, Jankipuram Extension, Lucknow 226031, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6413-8509","authenticated-orcid":true,"given":"Debabrata","family":"Mandal","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, National Institute of Pharmaceutical Education and Research Hajipur, Vaishali 844102, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1079-3385","authenticated-orcid":true,"given":"Subrata","family":"Das","sequence":"additional","affiliation":[{"name":"Applied Chemistry Laboratory, Department of Chemistry, National Institute of Technology Patna, Ashok Rajpath 800005, Bihar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2024,11,1]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1039\/D2RA04934A"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.2174\/1389557520999201123210025"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1007\/s10973-019-08884-4"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1039\/C7MH00920H"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2020.112801"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2014.10.008"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2009.07.014"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/slct.202004745"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1039\/c3ra22089c"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1002\/jccs.201800275"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.8b00775"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2012.02.017"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2024.138215"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6714151"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1134\/S1068162023060213"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2009.02279x"},{"key":"ref17\/cit17a","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0012112"},{"key":"ref17\/cit17b","doi-asserted-by":"publisher","DOI":"10.14202\/vetworld.2018.1409-1415"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03630.x"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2016.02.165"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.3389\/fitd.2022.837460"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.113606"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2018.05.014"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2020.115511"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2012.05.035"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.6b01447"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2014.12.027"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S196421"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.2174\/0929867322666150319120337"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/bi992553w"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/ja0455143"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-77570-8_12"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2010.04.017"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.259441296"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2012.09.019"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1042\/bse0510063"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4439(02)00076-5"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1007\/BF00928361"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpddr.2017.04.003"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1186\/s13568-022-01419-5"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.5.1988-1993.2005"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.2174\/1389450023347588"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms9040826"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-20509-9"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.2174\/1568026616666160930131737"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.2147\/AABC.S366111"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2017.02.015"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.228213"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.4c00670","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.4c00670","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T09:12:08Z","timestamp":1734081128000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.4c00670"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,1]]},"references-count":48,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12,13]]}},"alternative-id":["10.1021\/acsinfecdis.4c00670"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.4c00670","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,1]]}}}