{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:13:09Z","timestamp":1790737989279,"version":"4.1.0"},"reference-count":62,"publisher":"American Chemical Society (ACS)","issue":"9","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai Municipality","doi-asserted-by":"publisher","award":["20ZR1411600"],"award-info":[{"award-number":["20ZR1411600"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017291","name":"Zhongshan Science and Technology Bureau","doi-asserted-by":"publisher","award":["CXTD2023009"],"award-info":[{"award-number":["CXTD2023009"]}],"id":[{"id":"10.13039\/501100017291","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017291","name":"Zhongshan Science and Technology Bureau","doi-asserted-by":"publisher","award":["CXTD2024006"],"award-info":[{"award-number":["CXTD2024006"]}],"id":[{"id":"10.13039\/501100017291","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010097","name":"China Association for Science and Technology","doi-asserted-by":"publisher","award":["2022QNRC001"],"award-info":[{"award-number":["2022QNRC001"]}],"id":[{"id":"10.13039\/100010097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFA0804700"],"award-info":[{"award-number":["2021YFA0804700"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFA0804701"],"award-info":[{"award-number":["2021YFA0804701"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFA1800400"],"award-info":[{"award-number":["2023YFA1800400"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFA1800403"],"award-info":[{"award-number":["2023YFA1800403"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020781","name":"Bethune Ethicon Excellent Surgery Foundation","doi-asserted-by":"publisher","award":["CESS2021TC04"],"award-info":[{"award-number":["CESS2021TC04"]}],"id":[{"id":"10.13039\/501100020781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020732","name":"Innovative Research Team of High-level Local University in Shanghai","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020732","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22225702"],"award-info":[{"award-number":["22225702"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31901036"],"award-info":[{"award-number":["31901036"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32322048"],"award-info":[{"award-number":["32322048"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32471497"],"award-info":[{"award-number":["32471497"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82241013"],"award-info":[{"award-number":["82241013"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013105","name":"Shanghai Rising-Star Program","doi-asserted-by":"publisher","award":["22QA1411100"],"award-info":[{"award-number":["22QA1411100"]}],"id":[{"id":"10.13039\/501100013105","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["2021276"],"award-info":[{"award-number":["2021276"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012247","name":"Program of Shanghai Academic Research Leader","doi-asserted-by":"publisher","award":["22XD1420900"],"award-info":[{"award-number":["22XD1420900"]}],"id":[{"id":"10.13039\/501100012247","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Guangdong High-level New Research and Development Institute","award":["2019B090904008"],"award-info":[{"award-number":["2019B090904008"]}]},{"name":"Baoshan District Health Commission","award":["BSZK-2023-A03"],"award-info":[{"award-number":["BSZK-2023-A03"]}]},{"name":"Guangdong High-level Innovative Research Institute","award":["2021B0909050003"],"award-info":[{"award-number":["2021B0909050003"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2025,9,12]]},"DOI":"10.1021\/acsinfecdis.4c00891","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T08:29:30Z","timestamp":1754987370000},"page":"2398-2410","source":"Crossref","is-referenced-by-count":1,"title":["Dynamic Proteomic and PTMomic Characterization of Mycobacteria after Clinical Pharmaceutical Intervention"],"prefix":"10.1021","volume":"11","author":[{"given":"Jun","family":"Yin","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Zhongshan Hospital","place":["Shanghai, China"]},{"name":"Fudan University","place":["Shanghai, China"]},{"name":"Shanghai Key Laboratory of Lung Inflammation and Injury","place":["Shanghai, China"]},{"name":"Shanghai Institute of Infectious Disease and Biosecurity, Shanghai Respiratory Research Institute","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liming","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine","place":["Shanghai, China"]},{"name":"Shanghai Xuhui Central Hospital","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailong","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery","place":["Shanghai, China"]},{"name":"Wusong Central Hospital","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9712-2711","authenticated-orcid":true,"given":"Mingya","family":"Zhang","sequence":"additional","affiliation":[{"name":"State key Laboratory of Drug Research","place":["Shanghai, China"]},{"name":"Shanghai Institute of Materia Medica, Chinese Academy of Sciences","place":["Shanghai, China"]},{"name":"Department of Medicinal Chemistry, School of Pharmacy","place":["Shanghai, China"]},{"name":"Fudan University","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Zhongshan Hospital","place":["Shanghai, China"]},{"name":"Fudan University","place":["Shanghai, China"]},{"name":"Shanghai Key Laboratory of Lung Inflammation and Injury","place":["Shanghai, China"]},{"name":"Shanghai Institute of Infectious Disease and Biosecurity, Shanghai Respiratory Research Institute","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunbo","family":"Kan","sequence":"additional","affiliation":[{"name":"State key Laboratory of Drug Research","place":["Shanghai, China"]},{"name":"Shanghai Institute of Materia Medica, Chinese Academy of Sciences","place":["Shanghai, China"]},{"name":"Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, College of Pharmacy","place":["Lianyungang, China"]},{"name":"Jiangsu Ocean University","place":["Lianyungang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianxian","family":"Liu","sequence":"additional","affiliation":[{"name":"State key Laboratory of Drug Research","place":["Shanghai, China"]},{"name":"Shanghai Institute of Materia Medica, Chinese Academy of Sciences","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Zhongshan Hospital","place":["Shanghai, China"]},{"name":"Fudan University","place":["Shanghai, China"]},{"name":"Shanghai Key Laboratory of Lung Inflammation and Injury","place":["Shanghai, China"]},{"name":"Shanghai Institute of Infectious Disease and Biosecurity, Shanghai Respiratory Research Institute","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhao","sequence":"additional","affiliation":[{"name":"Zhongshan Institute for Drug Discovery","place":["Zhongshan, China"]},{"name":"Shanghai Institute of Materia Medica, Chinese Academy of Sciences","place":["Zhongshan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6024-9973","authenticated-orcid":true,"given":"Yi","family":"Li","sequence":"additional","affiliation":[{"name":"State key Laboratory of Drug Research","place":["Shanghai, China"]},{"name":"Shanghai Institute of Materia Medica, Chinese Academy of Sciences","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8895-7788","authenticated-orcid":true,"given":"Shiyang","family":"Shen","sequence":"additional","affiliation":[{"name":"State key Laboratory of Drug Research","place":["Shanghai, China"]},{"name":"Shanghai Institute of Materia Medica, Chinese Academy of Sciences","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6807-2647","authenticated-orcid":true,"given":"Lu","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Medicinal Chemistry, School of Pharmacy","place":["Shanghai, China"]},{"name":"Fudan University","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6784-9653","authenticated-orcid":true,"given":"Minjia","family":"Tan","sequence":"additional","affiliation":[{"name":"State key Laboratory of Drug Research","place":["Shanghai, China"]},{"name":"Shanghai Institute of Materia Medica, Chinese Academy of Sciences","place":["Shanghai, China"]},{"name":"Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, College of Pharmacy","place":["Lianyungang, China"]},{"name":"Jiangsu Ocean University","place":["Lianyungang, China"]},{"name":"Zhongshan Institute for Drug Discovery","place":["Zhongshan, China"]},{"name":"Shanghai Institute of Materia Medica, Chinese Academy of Sciences","place":["Zhongshan, China"]},{"name":"Baoshan Cancer Center","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanlin","family":"Song","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory of Lung Inflammation and Injury","place":["Shanghai, China"]},{"name":"Shanghai Institute of Infectious Disease and Biosecurity, Shanghai Respiratory Research Institute","place":["Shanghai, China"]},{"name":"Department of Pulmonary Medicine, Zhongshan Hospital","place":["Shanghai, China"]},{"name":"Fudan University","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijie","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Zhongshan Hospital","place":["Shanghai, China"]},{"name":"Fudan University","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Yu","family":"Xu","sequence":"additional","affiliation":[{"name":"State key Laboratory of Drug Research","place":["Shanghai, China"]},{"name":"Shanghai Institute of Materia Medica, Chinese Academy of Sciences","place":["Shanghai, China"]},{"name":"Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, College of Pharmacy","place":["Lianyungang, China"]},{"name":"Jiangsu Ocean University","place":["Lianyungang, China"]},{"name":"Zhongshan Institute for Drug Discovery","place":["Zhongshan, China"]},{"name":"Shanghai Institute of Materia Medica, Chinese Academy of Sciences","place":["Zhongshan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31882-3"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2020.8124"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2016.11.084"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2018.02.006"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/nrd4001"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1701102"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/srep34293"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.2174\/1389450116666150806124110"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2016.03.007"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1111\/febs.15582"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1002\/iub.1871"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.2174\/1568026619666190227182701"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00062-6"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/imo2.53"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M114.041962"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2014.11.010"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aao1478"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.7b00429"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2018.05.005"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-022-00409-3"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M112.018846"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M114.038380"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M115.051151"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.RA117.000296"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M116.065771"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.8b00213"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1128\/mSystems.00424-19"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.2217\/fmb-2016-5000"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/srep43858"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.723667"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2018.02.019"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.4161\/viru.22329"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2014.12.015"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1159\/000516509"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00151-8"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.15.0389"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/emi.2014.3"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.cimid.2020.101574"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/srep11910"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10102592"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2015.07.031"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1177\/2472555217698428"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1186\/1477-5956-8-59"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-43299-8"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.1c00791"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpha.2023.08.021"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.8b00898"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.RA117.000372"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.6b00342"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcpro.2025.100991"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-51232-w"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2023.112787"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.15252\/embr.202256052"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.123.322590"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2023.154941"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1126\/science.1163885"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02941-15"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0008589"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2011.08.013"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aal1803"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms9922"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2017.03.026"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.4c00891","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.4c00891","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T08:16:43Z","timestamp":1757665003000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.4c00891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,12]]},"references-count":62,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9,12]]}},"alternative-id":["10.1021\/acsinfecdis.4c00891"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.4c00891","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,12]]}}}