{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:17:37Z","timestamp":1790011057497,"version":"4.0.1"},"reference-count":51,"publisher":"American Chemical Society (ACS)","issue":"10","funder":[{"name":"Syngenta AG"},{"DOI":"10.13039\/501100006447","name":"Universit\u00e4t Z\u00fcrich","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006447","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006710","name":"Wayne State University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2015,10,9]]},"DOI":"10.1021\/acsinfecdis.5b00069","type":"journal-article","created":{"date-parts":[[2015,7,28]],"date-time":"2015-07-28T15:56:43Z","timestamp":1438099003000},"page":"479-486","source":"Crossref","is-referenced-by-count":16,"title":["Synthesis and Antiribosomal Activities of 4\u2032-\n                    <i>O<\/i>\n                    -, 6\u2032-\n                    <i>O<\/i>\n                    -, 4\u2033-\n                    <i>O<\/i>\n                    -, 4\u2032,6\u2032-\n                    <i>O<\/i>\n                    - and 4\u2033,6\u2033-\n                    <i>O<\/i>\n                    -Derivatives in the Kanamycin Series Indicate Differing Target Selectivity Patterns between the 4,5- and 4,6-Series of Disubstituted 2-Deoxystreptamine Aminoglycoside Antibiotics"],"prefix":"10.1021","volume":"1","author":[{"given":"Takayuki","family":"Kato","sequence":"first","affiliation":[{"name":"Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanyu","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youjin","family":"Teo","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Medizinische Mikrobiologie, Universit\u00e4t Z\u00fcrich, 8006 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reda","family":"Juskeviciene","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Medizinische Mikrobiologie, Universit\u00e4t Z\u00fcrich, 8006 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e9borah","family":"Perez-Fernandez","sequence":"additional","affiliation":[{"name":"Laboratorium f\u00fcr Organische Chemie, ETH Z\u00fcrich, 8093 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harish M.","family":"Shinde","sequence":"additional","affiliation":[{"name":"Laboratorium f\u00fcr Organische Chemie, ETH Z\u00fcrich, 8093 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumanth","family":"Salian","sequence":"additional","affiliation":[{"name":"Laboratorium f\u00fcr Organische Chemie, ETH Z\u00fcrich, 8093 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Bernet","sequence":"additional","affiliation":[{"name":"Laboratorium f\u00fcr Organische Chemie, ETH Z\u00fcrich, 8093 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Vasella","sequence":"additional","affiliation":[{"name":"Laboratorium f\u00fcr Organische Chemie, ETH Z\u00fcrich, 8093 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik C.","family":"B\u00f6ttger","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Medizinische Mikrobiologie, Universit\u00e4t Z\u00fcrich, 8006 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Crich","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2015,8,6]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0811258106"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2013.01.006"},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/978-3-7091-0215-2_20","volume-title":"Ribosomes: Structure, Function, and Dynamics","author":"Akbergenov R.","year":"2011"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1002\/ijch.201000003"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/937861"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1172\/JCI77424"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2005.085951"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022347"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/srep00159"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1007\/s10162-011-0288-x"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1039\/C4MD00119B"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/ng0793-289"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1086\/381133"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0707265105"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm658"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1204073109"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4112"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b02248"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01827-01814"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201402146"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2010.11.065"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/ol0497685"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/jm050368c"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.5b00248"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.27.90"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.26.412"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/jo00795a052"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/hlca.19910740842"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/0040-4039(96)01307-X"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/ol701581g"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/ol3028708"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/jo202264r"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6215(00)81894-7"},{"key":"ref34\/cit34","first-page":"53","volume-title":"Preparative Carbohydrate Chemistry","author":"Garegg P. J.","year":"1993"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/jo800396g"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1039\/c1ob06056b"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/hlca.200890167"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/0471264180.os058.08"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01326-12"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/35030019"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/bip.10414"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.4.1489-1496.2006"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.12.5112-5118.2005"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.200700271"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(02)01452-3"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/bi020130f"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1021\/jm981108g"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/ja972599h"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/ja011695m"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1021\/ja029736h"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/ol027288c"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.5b00069","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T16:02:35Z","timestamp":1681488155000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.5b00069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,6]]},"references-count":51,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2015,10,9]]}},"alternative-id":["10.1021\/acsinfecdis.5b00069"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.5b00069","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,6]]}}}