{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T02:24:07Z","timestamp":1773023047605,"version":"3.50.1"},"reference-count":69,"publisher":"American Chemical Society (ACS)","issue":"2","funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-11-LABX-0024"],"award-info":[{"award-number":["ANR-11-LABX-0024"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009120","name":"Centre International de Recherche aux Fronti\u00e8res de la Chimie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009120","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2017,2,10]]},"DOI":"10.1021\/acsinfecdis.5b00141","type":"journal-article","created":{"date-parts":[[2016,11,24]],"date-time":"2016-11-24T01:30:20Z","timestamp":1479951020000},"page":"119-131","source":"Crossref","is-referenced-by-count":8,"title":["A Redox-Active Fluorescent pH Indicator for Detecting <i>Plasmodium falciparum<\/i> Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs"],"prefix":"10.1021","volume":"3","author":[{"given":"Mouhamad","family":"Jida","sequence":"first","affiliation":[{"name":"UMR 7509 Centre National de la Recherche Scientifique and University of Strasbourg, European School of Chemistry, Polymers and Materials (ECPM), 25 rue Becquerel, F-67087 Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia P.","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Zentrum\rf\u00fcr Infektiologie, Parasitologie, Universit\u00e4t Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kar\u00e8ne","family":"Urgin","sequence":"additional","affiliation":[{"name":"UMR 7509 Centre National de la Recherche Scientifique and University of Strasbourg, European School of Chemistry, Polymers and Materials (ECPM), 25 rue Becquerel, F-67087 Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Ehrhardt","sequence":"additional","affiliation":[{"name":"UMR 7509 Centre National de la Recherche Scientifique and University of Strasbourg, European School of Chemistry, Polymers and Materials (ECPM), 25 rue Becquerel, F-67087 Strasbourg, France"},{"name":"Zentrum\rf\u00fcr Infektiologie, Parasitologie, Universit\u00e4t Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saravanan","family":"Mounien","sequence":"additional","affiliation":[{"name":"UMR 7509 Centre National de la Recherche Scientifique and University of Strasbourg, European School of Chemistry, Polymers and Materials (ECPM), 25 rue Becquerel, F-67087 Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurelia","family":"Geyer","sequence":"additional","affiliation":[{"name":"UMR 7509 Centre National de la Recherche Scientifique and University of Strasbourg, European School of Chemistry, Polymers and Materials (ECPM), 25 rue Becquerel, F-67087 Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mourad","family":"Elhabiri","sequence":"additional","affiliation":[{"name":"UMR 7509 Centre National de la Recherche Scientifique and University of Strasbourg, European School of Chemistry, Polymers and Materials (ECPM), 25 rue Becquerel, F-67087 Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Lanzer","sequence":"additional","affiliation":[{"name":"Zentrum\rf\u00fcr Infektiologie, Parasitologie, Universit\u00e4t Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7026-4034","authenticated-orcid":true,"given":"Elisabeth","family":"Davioud-Charvet","sequence":"additional","affiliation":[{"name":"UMR 7509 Centre National de la Recherche Scientifique and University of Strasbourg, European School of Chemistry, Polymers and Materials (ECPM), 25 rue Becquerel, F-67087 Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2016,12,7]]},"reference":[{"key":"ref1\/cit1","unstructured":"World Health Organization. ( (2014) World Malaria Report 2014,WHO Press,Geneva, Switzerland."},{"key":"ref2\/cit2","unstructured":"World Health Organization. ( (2010) Global Report on Antimalarial Drug Efficacy and Drug Resistance: 2000\u20132010,WHO Press,Geneva, Switzerland."},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/nature14412"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0808859"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0911317106"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2011.07855.x"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1126\/science.1205216"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/nature12876"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004382"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004789"},{"key":"ref11\/cit11","volume-title":"Guidelines for the Treatment of Malaria","author":"WHO","year":"2015","edition":"3"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(05)00077-8"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1126\/science.1074045"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1126\/science.1175667"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.614206"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1322965111"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2012.08.002"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-011-0906-0"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2010.04.001"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0110800"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/bi901034r"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/srep01734"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2010.2"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/jm7009292"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/bc000022a"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2003.08.005"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1039\/C4CC05328A"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/bi0013501"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.2174\/1567269043480744"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/S0162-0134(97)00086-X"},{"key":"ref31\/cit31","first-page":"3539","volume":"18","author":"Johann L.","year":"2012","journal-title":"Curr. Pharm. Des."},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/ac300065t"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02248-12"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M208648200"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1126\/science.3544220"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/ja201729z"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201600009"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00773-07"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4165(91)90201-Q"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4889(95)00064-Y"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.2001.2487"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(99)00264-6"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/jm0497545"},{"key":"ref44\/cit44","volume-title":"Enzyme Kinetics. Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems","author":"Segel I. H.","year":"1975"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200300639"},{"key":"ref46\/cit46a","first-page":"375","volume-title":"Apicomplexan Parasites \u2013 Molecular Approaches toward Targeted Drug Development","author":"Davioud-Charvet E.","year":"2011"},{"key":"ref46\/cit46b","unstructured":"(from the seriesDrug Discovery in Infectious Diseases(Selzer, P. M., Ed.),Wiley-VCH Verlag,Weinheim, Germany, ISBN 978-3-527-32731-7)."},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2014.6047"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.2174\/1381612811319140003"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1994.2448"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1021\/jm010268g"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2012.4625"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv509"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-012-0872-9"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.electacta.2006.03.054"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1002\/prac.19843260307"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.31.10.1507"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.12566"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/es702290a"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1039\/c1md00127b"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1179\/000349802125001834"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2003.09.008"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-6851(00)00262-0"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-6851(00)00261-9"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.02795"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1021\/bi00066a029"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(98)00031-3"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00410.2001"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M500777200"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.5b00141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T13:51:37Z","timestamp":1681480297000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.5b00141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,7]]},"references-count":69,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2,10]]}},"alternative-id":["10.1021\/acsinfecdis.5b00141"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.5b00141","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,7]]}}}