{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:13:13Z","timestamp":1790737993733,"version":"4.1.0"},"reference-count":79,"publisher":"American Chemical Society (ACS)","issue":"12","license":[{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100007780","name":"Indian Institute of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["BT\/ PR41348\/MED\/29\/1536\/2020"],"award-info":[{"award-number":["BT\/ PR41348\/MED\/29\/1536\/2020"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["BT\/PR13522\/CoE\/34\/27\/2015"],"award-info":[{"award-number":["BT\/PR13522\/CoE\/34\/27\/2015"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2025,12,12]]},"DOI":"10.1021\/acsinfecdis.5c00781","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T06:04:45Z","timestamp":1763359485000},"page":"3607-3619","source":"Crossref","is-referenced-by-count":3,"title":["Succinylation of GyrB Is a Mechanism Conferring Fluoroquinolone Resistance"],"prefix":"10.1021","volume":"11","author":[{"given":"Abodh Kumar","family":"Jha","sequence":"first","affiliation":[{"name":"Department of Microbiology and Cell Biology","place":["Bangalore, India"]},{"name":"Indian Institute of Science (IISc)","place":["Bangalore, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iqball","family":"Faheem","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Cell Biology","place":["Bangalore, India"]},{"name":"Indian Institute of Science (IISc)","place":["Bangalore, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9768-1505","authenticated-orcid":true,"given":"Valakunja","family":"Nagaraja","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Cell Biology","place":["Bangalore, India"]},{"name":"Indian Institute of Science (IISc)","place":["Bangalore, India"]},{"name":"Indian Institute of Science Education and Research (IISER)","place":["Bhopal, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,11,17]]},"reference":[{"key":"ref1\/cit1","first-page":"233","volume-title":"Major Infectious Diseases","volume":"6","author":"Bloom B. R.","year":"2017","edition":"3"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(03)00671-6"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70260-3"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.2174\/1568026033452537"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1111\/febs.17142"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.02510-23"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-016-1727-6"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0907925106"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks497"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/pr500859a"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.7b00429"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1111\/febs.15582"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200501023"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-39654-9"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0913482107"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/19.6.1176"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.13339"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aao1478"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2016.1169219"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1017\/S0033583598003424"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/31159"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/48.4.479"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.4.1281-1288.2004"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01958-13"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.529164"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/30.10.2144"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.8.2066"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70139-0"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.1.362"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkr566"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-11-78"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.06272-11"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkl704"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2007.01005.x"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkn355"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.resmic.2023.104093"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1093\/embo-reports\/kvf038"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1007\/s00203-003-0598-4"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2016705118"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.4c00880"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.1.118-125.2005"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20191661"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.02.195"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2004.09.003"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1128\/JB.182.2.377-384.2000"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.001058"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-022-00468-7"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-072711-165700"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1525055113"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1525047113"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.36.8.1708"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.11.2978"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00250-06"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.5.2008-2014.2005"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.4.1022-1025.2002"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1385\/1-59259-057-8:171"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.8.2720-2722.2002"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.40.9.2054"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-020-0320-7"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.73.11.3872"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.11.4772"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201510-690BC"},{"key":"ref63\/cit63","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/9781119593522.ch6","volume-title":"Bacterial Resistance to Antibiotics \u2212from Molecules to Man","author":"Drlica K.","year":"2019"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkg269"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.12.3441-3443.2000"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1021\/bi052130w"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.MGM2-0009-2013"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00036-08"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00050-09"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00541-09"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2024.10.007"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.2217\/epi-2021-0357"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1038\/NM1347"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1021\/bi800664x"},{"issue":"6","key":"ref75\/cit75","first-page":"751","volume":"86","author":"Manjunatha U. H.","year":"2006","journal-title":"J. Indian Inst. Sci."},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1099\/13500872-141-12-3029"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.15068"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2001.tb09451.x"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2016.020"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.5c00781","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.5c00781","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T09:12:30Z","timestamp":1765530750000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.5c00781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,17]]},"references-count":79,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12,12]]}},"alternative-id":["10.1021\/acsinfecdis.5c00781"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.5c00781","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,17]]}}}