{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T22:41:12Z","timestamp":1772577672212,"version":"3.50.1"},"reference-count":75,"publisher":"American Chemical Society (ACS)","issue":"9","funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1049716"],"award-info":[{"award-number":["APP1049716"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2016,9,9]]},"DOI":"10.1021\/acsinfecdis.6b00121","type":"journal-article","created":{"date-parts":[[2016,8,9]],"date-time":"2016-08-09T21:04:38Z","timestamp":1470776678000},"page":"651-663","source":"Crossref","is-referenced-by-count":23,"title":["Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in <i>Cryptococcus neoformans<\/i>"],"prefix":"10.1021","volume":"2","author":[{"given":"Ross D.","family":"Blundell","sequence":"first","affiliation":[{"name":"Australian Infectious Diseases Research\rCentre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon J.","family":"Williams","sequence":"additional","affiliation":[{"name":"Australian Infectious Diseases Research\rCentre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia"},{"name":"Institute for Molecular\rBioscience, The University of Queensland, Brisbane, Queensland 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha D. M.","family":"Arras","sequence":"additional","affiliation":[{"name":"Australian Infectious Diseases Research\rCentre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica L.","family":"Chitty","sequence":"additional","affiliation":[{"name":"Australian Infectious Diseases Research\rCentre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirsten L.","family":"Blake","sequence":"additional","affiliation":[{"name":"Australian Infectious Diseases Research\rCentre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J.","family":"Ericsson","sequence":"additional","affiliation":[{"name":"Australian Infectious Diseases Research\rCentre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia"},{"name":"Institute for Molecular\rBioscience, The University of Queensland, Brisbane, Queensland 4072, Australia"},{"name":"MX Beamlines, Australian Synchrotron, 800 Blackburn Road, Clayton, Victoria 3168, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nidhi","family":"Tibrewal","sequence":"additional","affiliation":[{"name":"College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536-0596, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jurgen","family":"Rohr","sequence":"additional","affiliation":[{"name":"College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536-0596, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y. Q. Andre E.","family":"Koh","sequence":"additional","affiliation":[{"name":"Australian Infectious Diseases Research\rCentre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Kappler","sequence":"additional","affiliation":[{"name":"Australian Infectious Diseases Research\rCentre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia"},{"name":"Centre for Metals in Biology, School of\rChemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avril A. B.","family":"Robertson","sequence":"additional","affiliation":[{"name":"Institute for Molecular\rBioscience, The University of Queensland, Brisbane, Queensland 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark S.","family":"Butler","sequence":"additional","affiliation":[{"name":"Institute for Molecular\rBioscience, The University of Queensland, Brisbane, Queensland 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew A.","family":"Cooper","sequence":"additional","affiliation":[{"name":"Institute for Molecular\rBioscience, The University of Queensland, Brisbane, Queensland 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bostjan","family":"Kobe","sequence":"additional","affiliation":[{"name":"Australian Infectious Diseases Research\rCentre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia"},{"name":"Institute for Molecular\rBioscience, The University of Queensland, Brisbane, Queensland 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James A.","family":"Fraser","sequence":"additional","affiliation":[{"name":"Australian Infectious Diseases Research\rCentre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2016,8,17]]},"reference":[{"key":"ref1\/cit1","unstructured":"UNAIDS. (2012) 2012 UNAIDS Report on the Global AIDS Epidemic, Joint United Nations Programme on HIV\/AIDS (UNAIDS)."},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328322ffac"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1080\/02681219880000661"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3762\/bjoc.4.31"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3074"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1126\/science.2649979"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1042\/bj1130515"},{"key":"ref8\/cit8","first-page":"593","volume":"13","author":"Clarke D. A.","year":"1953","journal-title":"Cancer Res."},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1007\/BF00965000"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002957"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1107\/S1744309110031659"},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1016\/S0021-9258(18)63020-0","volume":"245","author":"Lowy B.","year":"1970","journal-title":"J. Biol. Chem."},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.1988.tb02708.x-i1"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1024853"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(77)90245-5"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0082(92)90006-Z"},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0021-9258(18)65142-7","volume":"223","author":"Lieberman I.","year":"1956","journal-title":"J. Biol. Chem."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"25334","DOI":"10.1016\/S0021-9258(19)74396-8","volume":"268","author":"Poland B. W.","year":"1993","journal-title":"J. Biol. Chem."},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1995.0629"},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.1016\/S0021-9258(18)45891-7","volume":"267","author":"Liu F.","year":"1992","journal-title":"J. Biol. Chem."},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.1994.1195"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109561200"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.11.7078"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.47.29722"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/bi960426j"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2003.11.036"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1999.3473"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M106294200"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/2111198a0"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(68)90246-3"},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1016\/S0021-9258(19)73961-1","volume":"237","author":"Shigeura H. T.","year":"1962","journal-title":"J. Biol. Chem."},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1038\/212093a0"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.44.293"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.18.9431"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004261"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(58)90182-3"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1107\/S1744309113021921"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1042\/bj3410537"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1006\/prep.2001.1610"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-005-2539-9"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2011.1013"},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1128\/iai.1.5.446-454.1970","volume":"1","author":"Brubaker R. R.","year":"1970","journal-title":"Infect. Immunity"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-53-2-147"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00928-09"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1111\/j.1567-1364.2009.00600.x"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(73)90081-7"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M404232200"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00159-08"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.307884"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1128\/JB.05757-11"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/bi00908a022"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(84)90139-5"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2010.10.088"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M203730200"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/bi990159s"},{"key":"ref56\/cit56","volume-title":"Molecular Cloning: A Laboratory Manual","author":"Sambrook J.","year":"1989","edition":"2"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1099\/13500872-142-6-1557"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1006\/fgbi.1999.1180"},{"key":"ref59\/cit59","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1128\/jb.175.5.1405-1411.1993","volume":"175","author":"Toffaletti D. L.","year":"1993","journal-title":"J. Bacteriol."},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1080\/mmy.39.1.151.154"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.21.9.3179-3191.2001"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/175.2.414"},{"key":"ref64\/cit64","volume-title":"Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts","year":"2005","edition":"2"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00310-11"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.2.443-448.2000"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1128\/EC.2.5.1036-1045.2003"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1128\/EC.3.2.420-429.2004"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0122916"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444909047337"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444910045749"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1107\/S0021889807021206"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1107\/S090744490705024X"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444909052925"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444912001308"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444910007493"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.6b00121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T01:15:27Z","timestamp":1682126127000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.6b00121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,17]]},"references-count":75,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9,9]]}},"alternative-id":["10.1021\/acsinfecdis.6b00121"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.6b00121","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,17]]}}}