{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T01:24:05Z","timestamp":1793409845930,"version":"4.5.0"},"reference-count":26,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2019,2,18]],"date-time":"2019-02-18T00:00:00Z","timestamp":1550448000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,2,18]],"date-time":"2019-02-18T00:00:00Z","timestamp":1550448000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2019,2,18]],"date-time":"2019-02-18T00:00:00Z","timestamp":1550448000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/\/dx.doi.org\/10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["1R21AI132981-01"],"award-info":[{"award-number":["1R21AI132981-01"]}],"id":[{"id":"10.13039\/\/dx.doi.org\/10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/\/dx.doi.org\/10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["5F31AI129412-02"],"award-info":[{"award-number":["5F31AI129412-02"]}],"id":[{"id":"10.13039\/\/dx.doi.org\/10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/\/dx.doi.org\/10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["OPP1086203"],"award-info":[{"award-number":["OPP1086203"]}],"id":[{"id":"10.13039\/\/dx.doi.org\/10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/\/dx.doi.org\/10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["OPP1132451"],"award-info":[{"award-number":["OPP1132451"]}],"id":[{"id":"10.13039\/\/dx.doi.org\/10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Exxon Mobil Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Infect. Dis."],"published-print":{"date-parts":[[2019,4,12]]},"DOI":"10.1021\/acsinfecdis.8b00363","type":"journal-article","created":{"date-parts":[[2019,2,18]],"date-time":"2019-02-18T12:07:54Z","timestamp":1550491674000},"page":"515-520","source":"Crossref","is-referenced-by-count":14,"title":["The Adaptive Proline Response in <i>P. falciparum<\/i> Is Independent of <i>Pf<\/i>eIK1 and eIF2\u03b1 Signaling"],"prefix":"10.1021","volume":"5","author":[{"given":"Lola","family":"Fagbami","sequence":"first","affiliation":[{"name":"Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, United States"},{"name":"Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, Massachusetts 02114, United States"},{"name":"Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, Massachusetts 02142, United States"},{"name":"Harvard Graduate School of Arts and Sciences, 1350 Massachusetts Avenue, Cambridge, Massachusetts 02138, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy A.","family":"Deik","sequence":"additional","affiliation":[{"name":"Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, Massachusetts 02142, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kritika","family":"Singh","sequence":"additional","affiliation":[{"name":"Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, United States"},{"name":"Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, Massachusetts 02114, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia A.","family":"Santos","sequence":"additional","affiliation":[{"name":"Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, Massachusetts 02114, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan D.","family":"Herman","sequence":"additional","affiliation":[{"name":"Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selina E.","family":"Bopp","sequence":"additional","affiliation":[{"name":"Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9560-7643","authenticated-orcid":true,"given":"Amanda K.","family":"Lukens","sequence":"additional","affiliation":[{"name":"Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, Massachusetts 02142, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clary B.","family":"Clish","sequence":"additional","affiliation":[{"name":"Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, Massachusetts 02142, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dyann F.","family":"Wirth","sequence":"additional","affiliation":[{"name":"Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, United States"},{"name":"Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, Massachusetts 02142, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1105-689X","authenticated-orcid":true,"given":"Ralph","family":"Mazitschek","sequence":"additional","affiliation":[{"name":"Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, United States"},{"name":"Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, Massachusetts 02114, United States"},{"name":"Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, Massachusetts 02142, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2019,2,18]]},"reference":[{"key":"ref1\/cit1","unstructured":"WHO | World malaria report 2017, http:\/\/www.who.int\/malaria\/publications\/world-malaria-report-2017\/en\/."},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/415680a"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60034-8"},{"key":"ref4\/cit4","unstructured":"WHO | Status report on artemisinin and\nACT resistance (October 2016), http:\/\/www.who.int\/malaria\/publications\/atoz\/update-artemisinin-resistance-october2016\/en\/."},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/nature12876"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002450"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan4472"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-10-644"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1007\/128_2013_425"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2011.08.049"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpddr.2013.10.001"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2014.02.040"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.endeavour.2008.07.001"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aaa3575"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0511-2"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1007\/s00726-008-0061-6"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2012.5074"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.59.031805.133833"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-8-99"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01607-06"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0601876103"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1126\/science.781840"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.2307\/3280287"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.5.1803-1806.2004"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.5.1807-1810.2004"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2012.199133"}],"container-title":["ACS Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsinfecdis.8b00363","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T04:46:30Z","timestamp":1682138790000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsinfecdis.8b00363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,18]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4,12]]}},"alternative-id":["10.1021\/acsinfecdis.8b00363"],"URL":"https:\/\/doi.org\/10.1021\/acsinfecdis.8b00363","relation":{},"ISSN":["2373-8227","2373-8227"],"issn-type":[{"value":"2373-8227","type":"print"},{"value":"2373-8227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,18]]}}}