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There is an urgent need for new drugs to treat most infectious diseases. We were keen to see if there were lessons that we could learn across different disease areas and between the preclinical and clinical phases with the aim of exploring how we can improve and speed up the drug discovery, translational, and clinical development processes. We started with an introductory session on the current situation and then worked backward from clinical development to combination therapy, pharmacokinetic\/pharmacodynamic (PK\/PD) studies, drug discovery pathways, and new starting points and targets. This Viewpoint aims to capture some of the learnings.<\/jats:p>","DOI":"10.1021\/acsinfecdis.9b00371","type":"journal-article","created":{"date-parts":[[2019,12,6]],"date-time":"2019-12-06T09:11:07Z","timestamp":1575623467000},"page":"3-13","source":"Crossref","is-referenced-by-count":18,"title":["Setting Our Sights on Infectious Diseases"],"prefix":"10.1021","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3171-3519","authenticated-orcid":true,"given":"Manu","family":"De Rycker","sequence":"first","affiliation":[{"name":"University of Dundee , , ,","place":["Dundee, United Kingdom, DD1 5EH"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Horn","sequence":"additional","affiliation":[{"name":"University of Dundee , , ,","place":["Dundee, United Kingdom, DD1 5EH"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bree","family":"Aldridge","sequence":"additional","affiliation":[{"name":"Tufts University School of Medicine , 136 Harrison Avenue , , ,","place":["Boston, Massachusetts, United States, 02111"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard K.","family":"Amewu","sequence":"additional","affiliation":[{"name":"University of Ghana , , P.O. 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