{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T06:20:55Z","timestamp":1793946055203,"version":"4.8.0"},"reference-count":73,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T00:00:00Z","timestamp":1651536000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T00:00:00Z","timestamp":1651536000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T00:00:00Z","timestamp":1651536000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["5R0-ES031635"],"award-info":[{"award-number":["5R0-ES031635"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011082","name":"School of Medicine, University of North Carolina at Chapel Hill","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011082","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005355","name":"American Australian Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005355","id-type":"DOI","asserted-by":"publisher"}]},{"name":"North Carolina Biotech Center","award":["2016-IDG-1016"],"award-info":[{"award-number":["2016-IDG-1016"]}]},{"name":"Center for Regenerative Nanomedicine, Simpson Querrey Institute for BioNanotechnology, Northwestern University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2022,5,24]]},"DOI":"10.1021\/acsnano.1c06258","type":"journal-article","created":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T21:01:00Z","timestamp":1651611660000},"page":"7309-7322","source":"Crossref","is-referenced-by-count":27,"title":["Peptide Amphiphile Supramolecular Nanofibers Designed to Target Abdominal Aortic Aneurysms"],"prefix":"10.1021","volume":"16","author":[{"given":"Benjamin T.","family":"Ledford","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Virginia, Charlottesville, Virginia 22903, United States"},{"name":"Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam W.","family":"Akerman","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kui","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9420-6346","authenticated-orcid":true,"given":"David C.","family":"Gillis","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Virginia, Charlottesville, Virginia 22903, United States"},{"name":"Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenna M.","family":"Weiss","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnny","family":"Vang","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smaranda","family":"Willcox","sequence":"additional","affiliation":[{"name":"Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8042-0141","authenticated-orcid":true,"given":"Tristan D.","family":"Clemons","sequence":"additional","affiliation":[{"name":"Simpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, Illinois 60611, United States"},{"name":"Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4268-2148","authenticated-orcid":true,"given":"Hiroaki","family":"Sai","sequence":"additional","affiliation":[{"name":"Simpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, Illinois 60611, United States"},{"name":"Department of Materials Science and Engineering, Northwestern University, Evanston, Illinois 60208, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7916-1509","authenticated-orcid":true,"given":"Ruomeng","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R.","family":"Karver","sequence":"additional","affiliation":[{"name":"Simpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, Illinois 60611, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack D.","family":"Griffith","sequence":"additional","affiliation":[{"name":"Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"},{"name":"Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0410-0143","authenticated-orcid":true,"given":"Nick D.","family":"Tsihlis","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Virginia, Charlottesville, Virginia 22903, United States"},{"name":"Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22904, United States"},{"name":"Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5491-7442","authenticated-orcid":true,"given":"Samuel I.","family":"Stupp","sequence":"additional","affiliation":[{"name":"Simpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, Illinois 60611, United States"},{"name":"Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States"},{"name":"Department of Materials Science and Engineering, Northwestern University, Evanston, Illinois 60208, United States"},{"name":"Department of Medicine, Northwestern University, Chicago, Illinois 60611, United States"},{"name":"Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John S.","family":"Ikonomidis","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9049-4205","authenticated-orcid":true,"given":"Melina R.","family":"Kibbe","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Virginia, Charlottesville, Virginia 22903, United States"},{"name":"Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22904, United States"},{"name":"Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"},{"name":"Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,5,3]]},"reference":[{"key":"ref1\/cit1","unstructured":"CDC.Aortic Aneurysm Fact Sheet. https:\/\/www.cdc.gov\/dhdsp\/data_statistics\/fact_sheets\/fs_aortic_aneurysm.htm (accessed 2018-10-30)."},{"issue":"8","key":"ref2\/cit2","first-page":"538","volume":"91","author":"Keisler B.","year":"2015","journal-title":"Am. Fam Physician"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2015.07.074"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2018.01.003"},{"issue":"7","key":"ref5\/cit5","first-page":"1198","volume":"73","author":"Upchurch G. R.","year":"2006","journal-title":"Am. Fam Physician"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1053\/ejvs.2000.1210"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-007-9456-x"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2011.02699.x"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.1.96"},{"issue":"3","key":"ref10\/cit10","first-page":"993","volume":"150","author":"Lopez-Candales A.","year":"1997","journal-title":"Am. J. Pathol."},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M111.008128"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9593"},{"issue":"5","key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"209","DOI":"10.14712\/fb2017063050209","volume":"63","author":"Vasic N.","year":"2017","journal-title":"Folia Biol. (Praha)"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.464727"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1006\/cbir.1993.1149"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-14-0857"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2016.10.062"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1172\/JCI15334"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1172\/JCI113368"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.33549\/physiolres.933579"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2010.01.001"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2016.07.004"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2016.12.030"},{"issue":"6","key":"ref24\/cit24","first-page":"903","volume":"67","author":"Siennicka A.","year":"2016","journal-title":"J. Physiol Pharmacol"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.18.10.1625"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2017.04.028"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00028.2010"},{"key":"ref28\/cit28","unstructured":"Novartis Pharmaceuticals.ACZ885 for the Treatment of Abdominal Aortic Aneurysm (AAA). https:\/\/clinicaltrials.gov\/ct2\/show\/study\/NCT02007252?rslt=With&type=Intr&cond=Aortic+Aneurysm&rank=1&sect=X370156 (accessed 2018-10-31)."},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.09.055"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1007\/s10595-002-2513-0"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2017.05.041"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2016.03.008"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201403429"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2015.6363"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b06025"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b09243"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.201900066"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201801545"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2020.101310"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-019-0129-8"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201911782"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.2174\/092986710793213724"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1172\/JCI2182"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.14.8.1315"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.551572"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGENETICS.112.963082"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M806239200"},{"issue":"1","key":"ref48\/cit48","first-page":"11","volume":"16","author":"Aggarwal S.","year":"2011","journal-title":"Exp Clin Cardiol"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-007-7893-1_3"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000148367.08413.E9"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2005.01.012"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/S1054-8807(04)00009-2"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.308765"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2009.208835"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.517391"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.419929"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.126.2.563"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1172\/JCI115538"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M508736200"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202004042"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.2741\/3676"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.102185399"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2014.02.002"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.10.010"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00620.2011"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2011.11.1024"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2582"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.114.305115"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1340"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-4804(03)00193-8"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvaa037"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1107\/S0021889809002222"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b03878"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.1c06258","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.1c06258","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T18:14:18Z","timestamp":1727115258000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.1c06258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,3]]},"references-count":73,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5,24]]}},"alternative-id":["10.1021\/acsnano.1c06258"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.1c06258","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,3]]}}}