{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T12:50:34Z","timestamp":1793969434287,"version":"4.8.0"},"reference-count":50,"publisher":"American Chemical Society (ACS)","issue":"12","license":[{"start":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T00:00:00Z","timestamp":1637193600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T00:00:00Z","timestamp":1637193600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T00:00:00Z","timestamp":1637193600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100007279","name":"Shanghai Municipal Health Bureau","doi-asserted-by":"publisher","award":["XBR2011063"],"award-info":[{"award-number":["XBR2011063"]}],"id":[{"id":"10.13039\/501100007279","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82074031"],"award-info":[{"award-number":["82074031"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National training program for innovative talents of Traditional Chinese Medicine","award":["T20194828003"],"award-info":[{"award-number":["T20194828003"]}]},{"name":"Shanghai Talent Development Fund","award":["2018099"],"award-info":[{"award-number":["2018099"]}]},{"name":"Program for Professor of Special Appointment","award":["TP2020054"],"award-info":[{"award-number":["TP2020054"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2021,12,28]]},"DOI":"10.1021\/acsnano.1c07829","type":"journal-article","created":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T16:18:28Z","timestamp":1637252308000},"page":"20087-20104","source":"Crossref","is-referenced-by-count":152,"title":["Microneedle-Mediated Biomimetic Cyclodextrin Metal Organic Frameworks for Active Targeting and Treatment of Hypertrophic Scars"],"prefix":"10.1021","volume":"15","author":[{"given":"Tong","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolin","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang","family":"Ruan","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixia","family":"Pei","sequence":"additional","affiliation":[{"name":"Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teng","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyuan","family":"Ci","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyao","family":"Ruan","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanzhi","family":"He","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zehui","family":"He","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5303-2941","authenticated-orcid":true,"given":"Nianping","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1427-4868","authenticated-orcid":true,"given":"Yongtai","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,11,18]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31406-4"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c20667"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1039\/D0NR03494K"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2021.118187"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202013904"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2020.07.018"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201901065"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.05.038"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201801054"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b09573"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.1c00240"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1039\/C9TB01449G"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2018.05.097"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1080\/10611860600991993"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(01)00052-7"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2014.06.001"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.7150\/thno.29715"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/nn304235j"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2015.07.019"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.02.041"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1039\/C7RA02306E"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1093\/jbcr\/irab100"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1039\/C7CC03471G"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b06287"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrysgro.2016.07.004"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2018.09.003"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2015.10.010"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-018-2369-6"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1088\/0960-1317\/24\/11\/115015"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0503524102"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2009.01246.x"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2015.10.040"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.499"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1007\/s12010-014-0901-7"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00683.2014"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-03546-6"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-020-00407-6"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2009.18.12.45609"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2021.114263"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2018.09.028"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1097\/MJT.0000000000000392"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b01522"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1159\/000430385"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)00121-5"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13842"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2013.02.038"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.16250"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2388"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202004550"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2020.115935"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.1c07829","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T00:22:11Z","timestamp":1681690931000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.1c07829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,18]]},"references-count":50,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12,28]]}},"alternative-id":["10.1021\/acsnano.1c07829"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.1c07829","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,18]]}}}