{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T05:09:59Z","timestamp":1793941799049,"version":"4.8.0"},"reference-count":89,"publisher":"American Chemical Society (ACS)","issue":"7","license":[{"start":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T00:00:00Z","timestamp":1657152000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T00:00:00Z","timestamp":1657152000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T00:00:00Z","timestamp":1657152000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA206366"],"award-info":[{"award-number":["R01CA206366"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA243023"],"award-info":[{"award-number":["R01CA243023"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2022,7,26]]},"DOI":"10.1021\/acsnano.2c05195","type":"journal-article","created":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T15:04:30Z","timestamp":1657206270000},"page":"11374-11391","source":"Crossref","is-referenced-by-count":53,"title":["Greatly Enhanced CTC Culture Enabled by Capturing CTC Heterogeneity Using a PEGylated PDMS\u2013Titanium\u2013Gold Electromicrofluidic Device with Glutathione-Controlled Gentle Cell Release"],"prefix":"10.1021","volume":"16","author":[{"given":"Elyahb A.","family":"Kwizera","sequence":"first","affiliation":[{"name":"Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1923-4221","authenticated-orcid":true,"given":"Wenquan","family":"Ou","sequence":"additional","affiliation":[{"name":"Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sojeong","family":"Lee","sequence":"additional","affiliation":[{"name":"Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Stewart","sequence":"additional","affiliation":[{"name":"Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James G.","family":"Shamul","sequence":"additional","affiliation":[{"name":"Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangsheng","family":"Xu","sequence":"additional","affiliation":[{"name":"Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Tait","sequence":"additional","affiliation":[{"name":"Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Maryland 21201, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine H. R.","family":"Tkaczuk","sequence":"additional","affiliation":[{"name":"Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Maryland 21201, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0125-6086","authenticated-orcid":true,"given":"Xiaoming","family":"He","sequence":"additional","affiliation":[{"name":"Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, United States"},{"name":"Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Maryland 21201, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,7,7]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1804280"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2576"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/micronano.2017.104"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2018.04.002"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-020-00728-3"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/nn304719q"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201801131"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.8.4589"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-01666-2"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-017-0013-8"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms5764"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-018-0190-5"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-10122-2"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-018-0257-3"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/nature06385"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.01.014"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21051696"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-021-01328-7"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21615-4"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2017.166"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17101775"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1608461113"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1126\/science.1228522"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1039\/C7LC00038C"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2019.07.074"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2010.215"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.11.025"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1186\/bcr2333"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.03.027"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1186\/bcr3099"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3820"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3404"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.08.016"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2017.125"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1126\/science.1253533"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2014.133"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-2613"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-15-0145"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.5966\/sctm.2015-0048"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00094.2014"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2016.5432"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2014.06.022"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-13-0087"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202000259"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/nn506928p"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-020-2448-6"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-01500-9"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-018-0080-4"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-13441-6"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.5607\/en.2014.23.1.93"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2013.08.013"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2004.08.014"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.05.009"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.1c00083"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1007\/s10544-007-9130-y"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1063\/1.5007003"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1038\/s41929-021-00718-7"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c02953"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aba6712"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c03018"},{"key":"ref62\/cit62","unstructured":"Bloise, F. S.; Ferro, R. M.; Rojo, A. B.; Latasa, F. G.\n                      Solved Problems in Electromagnetics\n                      ; Springer: Berlin, 2016; pp 123\u2013125."},{"key":"ref63\/cit63","unstructured":"Haynes, W. M.\n                      CRC Handbook of Chemistry and Physics\n                      , 91st ed. Taylor & Francis: New York, 2010; pp 242\u2013246."},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1012539107"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/0026-2862(81)90084-4"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-12-501"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2014.366"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.8250"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1038\/s41698-017-0030-1"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.04.030"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2015.08.048"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1111\/cas.13246"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms3299"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2016.09.092"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1126\/science.1228522"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2013.03.004"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1002\/adbi.201800228"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15548-7"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.3390\/cells9081836"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21388"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2018180056"},{"key":"ref82\/cit82","first-page":"23","volume":"58","author":"Mujagi\u0107 Z.","year":"2004","journal-title":"Med. Arh."},{"key":"ref83\/cit83","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-012-1289-9"},{"key":"ref84\/cit84","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtm.2021.08.007"},{"key":"ref85\/cit85","doi-asserted-by":"publisher","DOI":"10.1038\/s41698-019-0095-0"},{"key":"ref86\/cit86","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1209327"},{"key":"ref87\/cit87","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2019.10.041"},{"key":"ref88\/cit88","doi-asserted-by":"publisher","DOI":"10.1038\/35102167"},{"key":"ref89\/cit89","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0530291100"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.2c05195","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.2c05195","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T07:57:56Z","timestamp":1682409476000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.2c05195"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,7]]},"references-count":89,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7,26]]}},"alternative-id":["10.1021\/acsnano.2c05195"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.2c05195","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,7]]}}}